Dean R. Madden

6.5k total citations · 4 hit papers
92 papers, 5.3k citations indexed

About

Dean R. Madden is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Dean R. Madden has authored 92 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 55 papers in Molecular Biology, 25 papers in Cellular and Molecular Neuroscience and 22 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Dean R. Madden's work include Neuroscience and Neuropharmacology Research (25 papers), Cystic Fibrosis Research Advances (21 papers) and Ion channel regulation and function (15 papers). Dean R. Madden is often cited by papers focused on Neuroscience and Neuropharmacology Research (25 papers), Cystic Fibrosis Research Advances (21 papers) and Ion channel regulation and function (15 papers). Dean R. Madden collaborates with scholars based in United States, Germany and Finland. Dean R. Madden's co-authors include Don C. Wiley, Joan C. Gorga, Theodore S. Jardetzky, D. C. Wiley, Jack L. Strominger, W S Lane, J L Strominger, Kari Keinänen, Patrick R. Cushing and Rupert Abele and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Dean R. Madden

91 papers receiving 5.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification of self peptides bound to purified HLA-B27

1991 731 citations Dean R. Madden et al. profile →
The Three-Dimensional Structure of Peptide-MHC Complexes

1995 663 citations Dean R. Madden profile →
The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

1992 577 citations Dean R. Madden et al. profile →
The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 554 citations Dean R. Madden et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dean R. Madden United States	30	2.8k	2.2k	870	636	437	92	5.3k
Martin S. Springer United States	38	2.0k 0.7×	1.8k 0.8×	442 0.5×	359 0.6×	591 1.4×	65	4.9k
Paul N. Barlow United Kingdom	50	2.5k 0.9×	3.7k 1.7×	221 0.3×	568 0.9×	625 1.4×	147	7.3k
Terry Farrah United States	22	3.0k 1.1×	2.0k 0.9×	393 0.5×	212 0.3×	461 1.1×	28	5.8k
Stephen Bottomley Australia	42	3.1k 1.1×	792 0.4×	780 0.9×	376 0.6×	311 0.7×	139	5.3k
Michael Tiemeyer United States	36	4.2k 1.5×	1.5k 0.7×	411 0.5×	431 0.7×	313 0.7×	109	5.7k
Toshisuke Kawasaki Japan	47	5.4k 1.9×	2.9k 1.3×	297 0.3×	784 1.2×	464 1.1×	179	8.0k
Hai‐Tao He France	33	2.8k 1.0×	1.8k 0.8×	337 0.4×	317 0.5×	162 0.4×	72	4.8k
Clifford D. Mol United States	26	5.0k 1.8×	609 0.3×	574 0.7×	478 0.8×	642 1.5×	31	6.3k
Xuewu Zhang United States	25	2.6k 0.9×	2.0k 0.9×	419 0.5×	346 0.5×	99 0.2×	54	4.3k
Eric A. Reits Netherlands	37	3.2k 1.1×	2.6k 1.2×	571 0.7×	342 0.5×	277 0.6×	69	6.5k

Countries citing papers authored by Dean R. Madden

Since Specialization

Citations

This map shows the geographic impact of Dean R. Madden's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dean R. Madden with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dean R. Madden more than expected).

Fields of papers citing papers by Dean R. Madden

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dean R. Madden. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dean R. Madden. The network helps show where Dean R. Madden may publish in the future.

Co-authorship network of co-authors of Dean R. Madden

This figure shows the co-authorship network connecting the top 25 collaborators of Dean R. Madden. A scholar is included among the top collaborators of Dean R. Madden based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dean R. Madden. Dean R. Madden is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

He, Susu, Kelli L. Hvorecny, Michael J. Ragusa, et al.. (2024). Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa. Nucleic Acids Research. 52(20). 12727–12747.

Madden, Dean R., et al.. (2023). Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets. Protein Science. 32(4). e4611–e4611. 3 indexed citations

Hampton, Thomas H., et al.. (2022). Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10. Journal of Biological Chemistry. 298(12). 102552–102552. 6 indexed citations

Hvorecny, Kelli L., Morgan S. A. Gilman, Gary E. Heussler, et al.. (2021). Biochemical and structural characterization of two cif-like epoxide hydrolases from Burkholderia cenocepacia. SHILAP Revista de lepidopterología. 3. 72–84. 3 indexed citations

Vasylieva, Natalia, Seiya Kitamura, Jie-Xian Dong, et al.. (2019). Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif). Analytica Chimica Acta. 1057. 106–113. 11 indexed citations

Hvorecny, Kelli L., Christopher D. Bahl, Seiya Kitamura, et al.. (2017). Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase. Structure. 25(5). 697–707.e4. 12 indexed citations

Clausen, Rasmus P., Andreas Mohr, Erik Riise, et al.. (2016). A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain. International Journal of Biological Macromolecules. 92. 779–787. 2 indexed citations

Koeppen, Katja, Bonita Coutermarsh, Dean R. Madden, & Bruce A. Stanton. (2014). Serum- and Glucocorticoid-induced Protein Kinase 1 (SGK1) Increases the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Airway Epithelial Cells by Phosphorylating Shank2E Protein. Journal of Biological Chemistry. 289(24). 17142–17150. 6 indexed citations

Amacher, Jeanine F., Ruizhi Zhao, Mark R. Spaller, & Dean R. Madden. (2014). Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain. PLoS ONE. 9(8). e103650–e103650. 14 indexed citations

10.

Cushing, Patrick R., et al.. (2012). Hybrid Organic–Inorganic Inhibitors of a PDZ Interaction that Regulates the Endocytic Fate of CFTR. Angewandte Chemie International Edition. 51(29). 7217–7220. 28 indexed citations

11.

Madden, Dean R. & Agnieszka Swiatecka‐Urban. (2012). Tissue-specific control of CFTR endocytosis by Dab2. Communicative & Integrative Biology. 5(5). 473–476. 13 indexed citations

12.

Navarro, M.V.A.S., Peter D. Newell, Petya V. Krasteva, et al.. (2011). Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis. PLoS Biology. 9(2). e1000588–e1000588. 149 indexed citations

13.

Park, Wooram, Dean R. Madden, Daniel N. Rockmore, & Gregory S. Chirikjian. (2010). Statistical Analysis and Deblurring of Class Averages in Single-Particle Electron Microscopy. Biophysical Journal. 98(3). 385a–385a. 1 indexed citations

14.

Nayeem, Naushaba, Yihong Zhang, Devin K. Schweppe, Dean R. Madden, & T.C. Green. (2009). A Nondesensitizing Kainate Receptor Point Mutant. Molecular Pharmacology. 76(3). 534–542. 28 indexed citations

15.

Gill, Avinash, et al.. (2008). Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists. Biochemistry. 47(52). 13831–13841. 21 indexed citations

16.

Madden, Dean R., N. Armstrong, Dmitri I. Svergun, Javier Pérez, & Patrice Vachette. (2005). Solution X-ray Scattering Evidence for Agonist- and Antagonist-induced Modulation of Cleft Closure in a Glutamate Receptor Ligand-binding Domain. Journal of Biological Chemistry. 280(25). 23637–23642. 21 indexed citations

17.

Madden, Dean R., Qing Cheng, Frank Rigo, et al.. (2004). Stereochemistry of Glutamate Receptor Agonist Efficacy: Engineering a Dual-Specificity AMPA/Kainate Receptor. Biochemistry. 43(50). 15838–15844. 22 indexed citations

18.

Pasternack, Arja, Sarah K. Coleman, James Féthière, et al.. (2003). Characterization of the functional role of the N‐glycans in the AMPA receptor ligand‐binding domain. Journal of Neurochemistry. 84(5). 1184–1192. 15 indexed citations

19.

Abele, Rupert, Kari Keinänen, & Dean R. Madden. (2000). Agonist-induced Isomerization in a Glutamate Receptor Ligand-binding Domain. Journal of Biological Chemistry. 275(28). 21355–21363. 97 indexed citations

20.

Abele, Rupert, Milla Lampinen, Kari Keinänen, & Dean R. Madden. (1998). Disulfide Bonding and Cysteine Accessibility in the α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Subunit GluRD. Journal of Biological Chemistry. 273(39). 25132–25138. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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