Fiachra Humphries

2.2k total citations · 1 hit paper
32 papers, 1.6k citations indexed

About

Fiachra Humphries is a scholar working on Immunology, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Fiachra Humphries has authored 32 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Immunology, 17 papers in Molecular Biology and 7 papers in Infectious Diseases. Recurrent topics in Fiachra Humphries's work include interferon and immune responses (16 papers), Inflammasome and immune disorders (11 papers) and Immune Response and Inflammation (6 papers). Fiachra Humphries is often cited by papers focused on interferon and immune responses (16 papers), Inflammasome and immune disorders (11 papers) and Immune Response and Inflammation (6 papers). Fiachra Humphries collaborates with scholars based in United States, Ireland and United Kingdom. Fiachra Humphries's co-authors include Shuo Yang, Bingwei Wang, Paul N. Moynagh, Katherine A. Fitzgerald, Zhaozhao Jiang, Liraz Shmuel-Galia, Ruth Wilson, Scott A. Shaffer, Paul R. Thompson and Natália Ketelut-Carneiro and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Fiachra Humphries

30 papers receiving 1.6k citations

Hit Papers

Succination inactivates gasdermin D and blocks pyroptosis 2020 2026 2022 2024 2020 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Succination inactivates gasdermin D and blocks pyroptosis
    2020 479 citations Fiachra Humphries, Liraz Shmuel-Galia et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Fiachra Humphries United States 15 1.0k 770 222 162 141 32 1.6k
Jueqi Chen United States 7 1.4k 1.4× 1.2k 1.5× 183 0.8× 300 1.9× 217 1.5× 9 2.0k
Liudmila Andreeva Germany 7 1.3k 1.2× 968 1.3× 187 0.8× 60 0.4× 147 1.0× 8 1.7k
Dhruv Chauhan Germany 10 1.7k 1.6× 1.2k 1.5× 221 1.0× 65 0.4× 186 1.3× 11 2.1k
Pontus Ørning United States 13 1.5k 1.4× 738 1.0× 88 0.4× 101 0.6× 240 1.7× 16 1.9k
Monika Schneider United States 11 1.4k 1.4× 1.5k 1.9× 187 0.8× 205 1.3× 177 1.3× 14 2.1k
SangJoon Lee South Korea 19 1.5k 1.5× 915 1.2× 259 1.2× 219 1.4× 380 2.7× 33 2.2k
Daniel Frank Australia 12 1.0k 1.0× 428 0.6× 70 0.3× 144 0.9× 201 1.4× 15 1.4k
Chuanping Wang United States 18 1.1k 1.1× 368 0.5× 140 0.6× 67 0.4× 204 1.4× 30 1.6k
Bettina Lee United States 5 984 0.9× 665 0.9× 63 0.3× 225 1.4× 133 0.9× 6 1.3k
Valérie Molinier‐Frenkel France 24 622 0.6× 671 0.9× 154 0.7× 89 0.5× 187 1.3× 61 1.6k

Countries citing papers authored by Fiachra Humphries

Since Specialization
Citations

This map shows the geographic impact of Fiachra Humphries's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fiachra Humphries with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fiachra Humphries more than expected).

Fields of papers citing papers by Fiachra Humphries

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fiachra Humphries. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fiachra Humphries. The network helps show where Fiachra Humphries may publish in the future.

Co-authorship network of co-authors of Fiachra Humphries

This figure shows the co-authorship network connecting the top 25 collaborators of Fiachra Humphries. A scholar is included among the top collaborators of Fiachra Humphries based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fiachra Humphries. Fiachra Humphries is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
O’Reilly, Maeve, Shruti Choudhary, Santoshkumar N. Patil, et al.. (2025). Nitrofuran-Based STING Inhibitors. ACS Omega. 10(36). 41693–41706. 2 indexed citations
2.
Singh, Anju, et al.. (2025). Triazole-based STING inhibitors. Bioorganic & Medicinal Chemistry. 132. 118484–118484.
3.
Humphries, Fiachra, et al.. (2025). Inflammasomopathies: mechanisms and disease signatures. Trends in Immunology. 46(5). 372–385.
4.
Humphries, Fiachra, et al.. (2024). Gasdermin D palmitoylation: to cleave or not to cleave?. Trends in Immunology. 45(6). 403–405. 4 indexed citations
5.
Yang, Shuo & Fiachra Humphries. (2024). Emerging roles of ECSIT in immunity and tumorigenesis. Trends in Cell Biology. 35(5). 426–438. 2 indexed citations
6.
Shmuel-Galia, Liraz, Fiachra Humphries, Tim Vierbuchen, et al.. (2023). The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis. Cell Metabolism. 35(8). 1441–1456.e9. 14 indexed citations
7.
Corkrey, Heather A., et al.. (2023). Platelets and SARS-CoV-2 During COVID-19: Immunity, Thrombosis, and Beyond. Circulation Research. 132(10). 1272–1289. 32 indexed citations
8.
Humphries, Fiachra. (2023). Biochemical Methods for Assessing Gasdermin D Inactivation in Macrophages. Methods in molecular biology. 2641. 125–133. 1 indexed citations
9.
Jiang, Yuying, Yingchao Hu, Rui Yang, et al.. (2022). Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade. Cell Reports. 41(4). 111553–111553. 35 indexed citations
10.
Humphries, Fiachra, Liraz Shmuel-Galia, Zhaozhao Jiang, et al.. (2021). A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection. Science Immunology. 6(59). 115 indexed citations
11.
Kim, Hera, Yashwanth Subbannayya, Fiachra Humphries, et al.. (2021). UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis. PLoS ONE. 16(10). e0258989–e0258989. 12 indexed citations
12.
Shmuel-Galia, Liraz, Fiachra Humphries, Xuqiu Lei, et al.. (2021). Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 54(6). 1137–1153.e8. 102 indexed citations
13.
Humphries, Fiachra, Bingwei Wang, Ashling Holland, et al.. (2021). ECSIT is a critical limiting factor for cardiac function. JCI Insight. 6(12). 13 indexed citations
14.
Balic, Jesse J., Kevin Luu, W. Samantha N. Jayasekara, et al.. (2020). STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression. Nature Communications. 11(1). 3816–3816. 101 indexed citations
15.
Humphries, Fiachra, Liraz Shmuel-Galia, Natália Ketelut-Carneiro, et al.. (2020). Succination inactivates gasdermin D and blocks pyroptosis. Science. 369(6511). 1633–1637. 479 indexed citations breakdown →
16.
Humphries, Fiachra, Ronan Bergin, Ruaidhrí Jackson, et al.. (2018). The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome. Nature Communications. 9(1). 1560–1560. 131 indexed citations
17.
Hanuszkiewicz, Anna, Paula Pittock, Fiachra Humphries, et al.. (2014). Identification of the Flagellin Glycosylation System in Burkholderia cenocepacia and the Contribution of Glycosylated Flagellin to Evasion of Human Innate Immune Responses. Journal of Biological Chemistry. 289(27). 19231–19244. 47 indexed citations
18.
Yang, Shuo, Bingwei Wang, Fiachra Humphries, et al.. (2014). The E3 Ubiquitin Ligase Pellino3 Protects against Obesity-Induced Inflammation and Insulin Resistance. Immunity. 41(6). 973–987. 48 indexed citations
19.
Humphries, Fiachra, Shuo Yang, Bingwei Wang, & Paul N. Moynagh. (2014). RIP kinases: key decision makers in cell death and innate immunity. Cell Death and Differentiation. 22(2). 225–236. 197 indexed citations
20.
Yang, Shuo, Bingwei Wang, Fiachra Humphries, et al.. (2013). Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis. Nature Immunology. 14(9). 927–936. 90 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Jueqi Chen Breakdown of academic impact, for papers by Liudmila Andreeva Breakdown of academic impact, for papers by Dhruv Chauhan Breakdown of academic impact, for papers by Pontus Ørning Breakdown of academic impact, for papers by Monika Schneider Breakdown of academic impact, for papers by SangJoon Lee Breakdown of academic impact, for papers by Daniel Frank Breakdown of academic impact, for papers by Chuanping Wang Breakdown of academic impact, for papers by Bettina Lee Breakdown of academic impact, for papers by Valérie Molinier‐Frenkel
Rankless by CCL
2026