Ernesto Canalis

32.3k citations

332 papers · 25.3k indexed · 8 hit papers · h-index 87

Impact in

Orthopedics and Sports Medicine top 0.05%
- Bone health and osteoporosis research
Endocrinology, Diabetes and Metabolism top 0.1%
- Growth Hormone and Insulin-like Growth Factors

Papers in

Endocrinology, Diabetes and Metabolism 102
- Growth Hormone and Insulin-like Growth Factors 83
Orthopedics and Sports Medicine 39
- Bone health and osteoporosis research 37

Co-authors: Thomas L. McCarthy Andrea Giustina Anne M. Delany Stefano Zanotti Gherardo Mazziotti Elisabetta Gazzerro John P. Bilezikian Lawrence G. Raisz
Journals: Endocrinology (79 papers)Journal of Biological Chemistry (33 papers)Bone (27 papers)Journal of Cellular Physiology (20 papers)Journal of Cellular Biochemistry (19 papers)
Partner nations: United States Italy Brazil

In The Last Decade

Ernesto Canalis

331 papers receiving 24.6k citations

Hit Papers

8 papers align trajectories log scale

Growth Hormone, Insulin-Like Growth Factors, and the Skeleton 2008 · 669 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2008 Endocrine Reviews
2007 Osteoporosis International
2007 New England Journal of Medicine
2007 Journal of Bone and Mineral Research
2003 Endocrine Reviews
1988 Journal of Clinical Investigation
1988 Endocrinology
1987 Journal of Biological Chemistry

Peers

Countries citing papers authored by Ernesto Canalis

Since Specialization

Citations

This map shows the geographic impact of Ernesto Canalis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ernesto Canalis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ernesto Canalis more than expected).

Fields of papers citing papers by Ernesto Canalis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ernesto Canalis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ernesto Canalis. The network helps show where Ernesto Canalis may publish in the future.

Co-authors

The 25 scholars most cited alongside Ernesto Canalis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ernesto Canalis Line = papers co-authored together Ernesto Canalis links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Use of antisense oligonucleotides to target Notch3 in skeletal cells PLoS ONE ·Ernesto Canalis, Michele Carrer, Tabitha Eller, Lauren Schilling, Jungeun Yu	2022	5
2	Role of nuclear factor of activated T cells in chondrogenesis osteogenesis and osteochondroma formation Journal of Endocrinological Investigation ·Ernesto Canalis, Lauren Schilling, Tabitha Eller, Jungeun Yu	2022	2
3	Protease-Activated Receptor 1 Deletion Causes Enhanced Osteoclastogenesis in Response to Inflammatory Signals through a Notch2-Dependent Mechanism The Journal of Immunology ·Sandra Jastrzebski, Judith Kalinowski, Se Hwan Mun, Bongjin Shin, Naga Suresh Adapala, Christian E. Jacome-Galarza, Faryal Mirza, Héctor L. Aguila, Hicham Drissi, Archana Sanjay, Ernesto Canalis, Sun‐Kyeong Lee, Joseph Lorenzo	2019	8
4	The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α Journal of Biological Chemistry ·Jungeun Yu, Ernesto Canalis	2019	17
5	An antibody to Notch3 reverses the skeletal phenotype of lateral meningocele syndrome in male mice Journal of Cellular Physiology ·Jungeun Yu, Christian W. Siebel, Lauren Schilling, Ernesto Canalis	2019	17
6	Glucocorticoids inhibit notch target gene expression in osteoblasts Journal of Cellular Biochemistry ·Stefano Zanotti, Jungeun Yu, Suyash Adhikari, Ernesto Canalis	2018	22
7	Nuclear factor of activated T cells 2 is required for osteoclast differentiation and function in vitro but not in vivo Journal of Cellular Biochemistry ·Jungeun Yu, Stefano Zanotti, Lauren Schilling, Ernesto Canalis	2018	10
8	Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis American Journal Of Pathology ·Jungeun Yu, Stefano Zanotti, Lauren Schilling, Chris Schoenherr, Aris N. Economides, Archana Sanjay, Ernesto Canalis	2018	4
9	Notch in skeletal physiology and disease Osteoporosis International ·Ernesto Canalis	2018	69
10	Parathyroid hormone inhibits Notch signaling in osteoblasts and osteocytes Bone ·Stefano Zanotti, Ernesto Canalis	2017	32
11	Sustained Notch2 signaling in osteoblasts, but not in osteoclasts, is linked to osteopenia in a mouse model of Hajdu-Cheney syndrome Journal of Biological Chemistry ·Stefano Zanotti, Jungeun Yu, Archana Sanjay, Lauren Schilling, Chris Schoenherr, Aris N. Economides, Ernesto Canalis	2017	27
12	The Hajdu Cheney Mutation Is a Determinant of B-Cell Allocation of the Splenic Marginal Zone American Journal Of Pathology ·Jungeun Yu, Stefano Zanotti, Bhavita Walia, Evan R. Jellison, Archana Sanjay, Ernesto Canalis	2017	9
13	The Heparin-binding Domain of IGFBP-2 Has Insulin-like Growth Factor Binding-independent Biologic Activity in the Growing Skeleton Journal of Biological Chemistry ·Masanobu Kawai, Anne Breggia, Victoria DeMambro, Xinchun Shen, Ernesto Canalis, Mary Bouxsein, Wesley G. Beamer, David R. Clemmons, Clifford J. Rosen	2011	50
14	A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity Proceedings of the National Academy of Sciences ·R. Scott Pearsall, Ernesto Canalis, Milton Cornwall-Brady, Kathryn Underwood, Brendan Haigis, Jeffrey A. Ucran, Ravindra Kumar, Eileen G. Pobre, Asya V. Grinberg, Eric D. Werner, Vaida Glatt, Lisa Stadmeyer, Deanna Smith, Jasbir Seehra, Mary Bouxsein	2008	7
15	Glucocorticoid Suppression of IGF I Transcription in Osteoblasts Molecular Endocrinology ·Anne M. Delany, Deena Durant, Ernesto Canalis	2001	115
16	Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts*This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil). Endocrinology* ·Renata C. Pereira, F. Blanquaert, Ernesto Canalis	1999	29
17	Interleukin 6 is autoregulated by transcriptional mechanisms in cultures of rat osteoblastic cells. Journal of Clinical Investigation ·Nathalie Franchimont, Sheila Rydziel, Ernesto Canalis	1997	55
18	Cortisol enhances the transcription of insulin-like growth factor-binding protein-6 in cultured osteoblasts. Endocrinology ·Bari Gabbitas, Ernesto Canalis	1996	35
19	Expression and growth factor regulation of platelet-derived growth factor B transcripts in primary osteoblast cell cultures. Endocrinology ·Sheila Rydziel, Ernesto Canalis	1996	13
20	Isoform-specific regulation of platelet-derived growth factor activity and binding in osteoblast-enriched cultures from fetal rat bone. Journal of Clinical Investigation ·Thomas L. McCarthy, William F. Kusmik, Ernesto Canalis	1992	50

About Ernesto Canalis

Ernesto Canalis is a scholar working on Endocrinology, Diabetes and Metabolism, Orthopedics and Sports Medicine, Oncology, Molecular Biology and Rheumatology, having authored 332 papers that have together received 25.3k indexed citations. Recurring topics across this work include Bone Metabolism and Diseases (138 papers), TGF-β signaling in diseases (105 papers), Bone health and treatments (100 papers), Growth Hormone and Insulin-like Growth Factors (83 papers), Bone health and osteoporosis research (37 papers), Developmental Biology and Gene Regulation (34 papers), Cancer, Hypoxia, and Metabolism (26 papers) and Connective tissue disorders research (22 papers). The work is most often cited by research in Orthopedics and Sports Medicine (5.2k citations), Endocrinology, Diabetes and Metabolism (5.5k citations), Oncology (6.8k citations), Rheumatology (3.6k citations) and Molecular Biology (14.5k citations). Ernesto Canalis has collaborated with scholars based in United States, Italy and Brazil. Frequent co-authors include Thomas L. McCarthy, Andrea Giustina, Anne M. Delany, Stefano Zanotti, Gherardo Mazziotti, Elisabetta Gazzerro, John P. Bilezikian, Lawrence G. Raisz, Janet M. Hock and Sheila Rydziel. Their work appears in journals such as Endocrinology, Journal of Biological Chemistry, Bone, Journal of Cellular Physiology and Journal of Cellular Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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