Eric Haaksma

2.3k total citations · 1 hit paper
33 papers, 1.8k citations indexed

About

Eric Haaksma is a scholar working on Molecular Biology, Organic Chemistry and Immunology. According to data from OpenAlex, Eric Haaksma has authored 33 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Molecular Biology, 11 papers in Organic Chemistry and 10 papers in Immunology. Recurrent topics in Eric Haaksma's work include Receptor Mechanisms and Signaling (16 papers), Chemical Synthesis and Analysis (12 papers) and Mast cells and histamine (10 papers). Eric Haaksma is often cited by papers focused on Receptor Mechanisms and Signaling (16 papers), Chemical Synthesis and Analysis (12 papers) and Mast cells and histamine (10 papers). Eric Haaksma collaborates with scholars based in Austria, Netherlands and Germany. Eric Haaksma's co-authors include Rob Leurs, Iwan J. P. de Esch, Oliver Kraemer, Michael P. Sanderson, Andreas Zoephel, Guenther R. Adolf, Flavio Solca, Frank Himmelsbach, Gerd Bader and Christian Klein and has published in prestigious journals such as Biophysical Journal, Journal of Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

In The Last Decade

Eric Haaksma

33 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker

2012 684 citations Flavio Solca, Andreas Zoephel et al. Journal of Pharmacology and Experimental Therapeutics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Eric Haaksma Austria	17	1.0k	574	455	355	278	33	1.8k
Bi‐Ching Sang United States	18	1.2k 1.2×	711 1.2×	206 0.5×	337 0.9×	167 0.6×	30	2.2k
Jeffrey R. Simard Germany	22	1.5k 1.4×	533 0.9×	250 0.5×	386 1.1×	180 0.6×	42	2.0k
Elena Ardini Italy	21	1.0k 1.0×	537 0.9×	343 0.8×	211 0.6×	123 0.4×	38	1.6k
Eugene L. Stewart United States	20	870 0.8×	229 0.4×	207 0.5×	377 1.1×	183 0.7×	47	2.2k
David Uehling Canada	27	2.3k 2.2×	800 1.4×	155 0.3×	756 2.1×	195 0.7×	46	3.2k
Octerloney B. McDonald United States	15	937 0.9×	653 1.1×	265 0.6×	398 1.1×	166 0.6×	21	1.7k
R.J. Skene United States	22	1.4k 1.3×	816 1.4×	171 0.4×	485 1.4×	209 0.8×	34	2.5k
K. Huber United Kingdom	26	1.9k 1.8×	665 1.2×	168 0.4×	518 1.5×	169 0.6×	60	3.0k
Kevin Kish United States	20	930 0.9×	265 0.5×	240 0.5×	381 1.1×	209 0.8×	38	2.0k
Brian Dymock Singapore	30	1.8k 1.7×	513 0.9×	121 0.3×	553 1.6×	502 1.8×	78	2.9k

Countries citing papers authored by Eric Haaksma

Since Specialization

Citations

This map shows the geographic impact of Eric Haaksma's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric Haaksma with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric Haaksma more than expected).

Fields of papers citing papers by Eric Haaksma

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric Haaksma. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric Haaksma. The network helps show where Eric Haaksma may publish in the future.

Co-authorship network of co-authors of Eric Haaksma

This figure shows the co-authorship network connecting the top 25 collaborators of Eric Haaksma. A scholar is included among the top collaborators of Eric Haaksma based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric Haaksma. Eric Haaksma is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Sanderson, Michael P., Joshua F. Apgar, Pilar Garin‐Chesa, et al.. (2015). BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis. Molecular Cancer Therapeutics. 14(12). 2762–2772. 16 indexed citations

Solca, Flavio, Andreas Zoephel, Gerd Bader, et al.. (2012). Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker. Journal of Pharmacology and Experimental Therapeutics. 343(2). 342–350. 684 indexed citations breakdown →

Schultes, Sabine, Harald Engelhardt, Luc Roumen, et al.. (2012). Combining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR–Ligand Binding Modes. ChemMedChem. 8(1). 49–53. 6 indexed citations

Schultes, Sabine, Chris de Graaf, Eric Haaksma, et al.. (2010). Ligand efficiency as a guide in fragment hit selection and optimization. Drug Discovery Today Technologies. 7(3). e157–e162. 179 indexed citations

Demel, Michael, Oliver Kraemer, Peter Ettmayer, Eric Haaksma, & Gerhard F. Ecker. (2010). Ensemble Rule‐Based Classification of Substrates of the Human ABC‐Transporter ABCB1 Using Simple Physicochemical Descriptors. Molecular Informatics. 29(3). 233–242. 15 indexed citations

Demel, Michael, Oliver H. Krämer, Peter Ettmayer, Eric Haaksma, & Gerhard F. Ecker. (2009). Predicting Ligand Interactions with ABC Transporters in ADME. Chemistry & Biodiversity. 6(11). 1960–1969. 30 indexed citations

Engelhardt, Harald, Rogier A. Smits, Rob Leurs, Eric Haaksma, & Iwan J. P. de Esch. (2009). A new generation of anti-histamines: Histamine H4 receptor antagonists on their way to the clinic.. PubMed. 12(5). 628–43. 36 indexed citations

Lim, Herman D., Enade Perdana Istyastono, Giuseppe Romeo, et al.. (2009). Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: Synthesis, pharmacological evaluation, and cross-target QSAR studies. Bioorganic & Medicinal Chemistry. 17(11). 3987–3994. 29 indexed citations

Demel, Michael, et al.. (2008). In silicoprediction of substrate properties for ABC-multidrug transporters. Expert Opinion on Drug Metabolism & Toxicology. 4(9). 1167–1180. 33 indexed citations

10.

Smits, Rogier A., Iwan J. P. de Esch, Obbe P. Zuiderveld, et al.. (2008). Discovery of Quinazolines as Histamine H₄Receptor Inverse Agonists Using a Scaffold Hopping Approach. Journal of Medicinal Chemistry. 51(24). 7855–7865. 80 indexed citations

11.

Lim, Herman D., Aldo Jongejan, Remko A. Bakker, et al.. (2008). Phenylalanine 169 in the Second Extracellular Loop of the Human Histamine H4 Receptor Is Responsible for the Difference in Agonist Binding between Human and Mouse H4 Receptors. Journal of Pharmacology and Experimental Therapeutics. 327(1). 88–96. 41 indexed citations

12.

Jongejan, Aldo, Martijn Bruysters, Juan Antonio Ballesteros‐Cánovas, et al.. (2005). Linking agonist binding to histamine H1 receptor activation. Nature Chemical Biology. 1(2). 98–103. 76 indexed citations

13.

Ries, Uwe J., Henning Priepke, Norbert Hauel, et al.. (2003). Heterocyclic thrombin inhibitors. Part 1: design and synthesis of amidino-phenoxy quinoline derivatives. Bioorganic & Medicinal Chemistry Letters. 13(14). 2291–2295. 15 indexed citations

14.

Ballesteros‐Cánovas, Juan Antonio, Xavier Deupí, Mireia Olivella, Eric Haaksma, & Leonardo Pardo. (2000). Serine and Threonine Residues Bend α-Helices in the χ1=g− Conformation. Biophysical Journal. 79(5). 2754–2760. 153 indexed citations

15.

Fox, Thomas & Eric Haaksma. (2000). Computer based screening of compound databases: 1. Preselection of benzamidine-based thrombin inhibitors. Journal of Computer-Aided Molecular Design. 14(5). 411–425. 14 indexed citations

16.

Daura, Xavier, Eric Haaksma, & Wilfred F. van Gunsteren. (2000). Factor Xa: Simulation studies with an eye to inhibitor design. Journal of Computer-Aided Molecular Design. 14(6). 507–529. 8 indexed citations

17.

Haaksma, Eric, Gabriëlle M. Donné-Op den Kelder, P. Vernooijs, & H. Timmerman. (1992). A theoretical study concerning the mode of interaction of the histamine H2-agonist dimaprit. Journal of Molecular Graphics. 10(2). 79–87. 3 indexed citations

18.

Haaksma, Eric, et al.. (1991). Theoretical Analysis of the Activity of Dimaprit Derivatives on the H2-Receptor. Birkhäuser Basel eBooks. 33. 315–324. 4 indexed citations

19.

Haaksma, Eric, Rob Leurs, & H. Timmerman. (1990). Histamine receptors: subclasses and specific ligands. Pharmacology & Therapeutics. 47(1). 73–104. 60 indexed citations

20.

Haaksma, Eric, et al.. (1988). Quantum Chemical Studies of H₂‐Antagonist‐Receptor Complexes. Cimetidine and Related Compounds. Quantitative Structure-Activity Relationships. 7(1). 7–12. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact