Elena Aïkawa

43.7k citations

261 papers · 22.1k indexed · 8 hit papers · h-index 78

Impact in

Cardiology and Cardiovascular Medicine top 0.1%
- Cardiac Valve Diseases and Treatments
- Cardiac Fibrosis and Remodeling
Immunology top 0.2%
- Atherosclerosis and Cardiovascular Diseases
- Immune cells in cancer

Papers in

Cardiology and Cardiovascular Medicine 102
- Cardiac Valve Diseases and Treatments 81
Immunology and Allergy 18
- Cell Adhesion Molecules Research 18

Co-authors: Ralph Weissleder Peter Libby Filip K. Świrski Matthias Nahrendorf Masanori Aikawa Mikäel J. Pittet Jose‐Luiz Figueiredo Joshua D. Hutcheson
Journals: Circulation (31 papers)Arteriosclerosis Thrombosis and Vascular Biology (28 papers)Frontiers in Cardiovascular Medicine (28 papers)Circulation Research (12 papers)European Heart Journal (9 papers)
Partner nations: United States Netherlands United Kingdom

In The Last Decade

Elena Aïkawa

253 papers receiving 21.8k citations

Hit Papers

8 papers align trajectories log scale

Endothelial to Mesenchymal Transition in Cardiovascular Disease 2019 · 409 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Journal of the American College of Cardiology
2019 Journal of the American College of Cardiology
2016 Nature Materials
2011 Circulation
2009 Science
2007 Circulation
2007 Journal of Clinical Investigation
2007 The Journal of Experimental Medicine

Peers

Countries citing papers authored by Elena Aïkawa

Since Specialization

Citations

This map shows the geographic impact of Elena Aïkawa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elena Aïkawa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elena Aïkawa more than expected).

Fields of papers citing papers by Elena Aïkawa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elena Aïkawa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elena Aïkawa. The network helps show where Elena Aïkawa may publish in the future.

Co-authors

The 25 scholars most cited alongside Elena Aïkawa, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Elena Aïkawa Line = papers co-authored together Elena Aïkawa links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Spermidine Enhances Mitochondrial Function and Mitigates Aortic Valve Calcification JACC Basic to Translational Science ·Greer Gilman, 罗翊, Сергеева Бэлла Владимировна, Kyoung‐Hee Choi, Dae‐Hee Kim, Jong‐Min Song, Duk‐Hyun Kang, Jae‐Kwan Song, Jiyoung Yu, Kyunggon Kim, Sahmin Lee, Elena Aïkawa	2025	1
2	Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis Frontiers in Cardiovascular Medicine ·G. Nagaveni, Anna Seliverstova, Liang Zhao, Ojārs Bušs, Faiza Zineb Boukhatem, Nicole Felix, Giuliano Generoso, Rhanderson Cardoso, Adrien Lupieri, Elena Aïkawa, Robert A. Levine, Maria Carmo Pereira Nunes	2025	0
3	Intracellular proteomics and extracellular vesiculomics as a metric of disease recapitulation in 3D-bioprinted aortic valve arrays Science Advances ·Cassandra L. Clift, Mark C. Blaser, V. and Mao, Mandy E. Turner, Abhijeet R. Sonawane, Tan Pham, Jason L. Andresen, Owen S. Fenton, Joshua M. Grolman, Ifigeneia Giannadaki, Fabrizio Buffolo, Frederick J. Schoen, Jesper Hjortnaes, Jochen D. Muehlschlegel, David Mooney, Masanori Aikawa, Sasha A. Singh, Róbert Langer, Elena Aïkawa	2024	10
4	Side- and Disease-Dependent Changes in Human Aortic Valve Cell Population and Transcriptomic Heterogeneity Determined by Single-Cell RNA Sequencing Genes ·Nicolas Villa-Roel, C.-S. Park, Aitor Andueza, Kyung In Baek, 修一本多, Mark C. Blaser, Bradley G. Leshnower, Ajit P. Yoganathan, Elena Aïkawa, Hanjoong Jo	2024	2
5	Obesity and age are transmission risk factors for SARS-CoV-2 infection among exposed individuals PNAS Nexus ·Joan T. Matamalas, Sarvesh Chelvanambi, Julius L. Decano, Zhengtao Guo, Arda Halu, 基彰青木, Elena Aïkawa, Rajeev Malhotra, Masanori Aikawa	2024	2
6	Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold Communications Biology ·Magdi H. Yacoub, Piero Alexander Medina Herrera, Jolanda Kluin, Antonio Lisboa Leitão de Sousa, Ulrich A. Stock, 昌蕾, Padmini Sarathchandra, Elena Aïkawa, J. W. Jervey, Adrian H. Chester, Cora-Lise Pichon, 俊吾山田, Jiang shuochen, Wei Li, Gaetano Burriesci, Jia-Fei Zhang, Soha Romeih, Najma Latif	2023	4
7	The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis Nature Reviews Cardiology ·Karan Sud, Navneet Narula, Elena Aïkawa, Eloisa Arbustini, Philippe Pîbarot, Giampaolo Merlini, Robert S. Rosenson, Surya V. Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Van Vo Kim Hieu, Nancy Côté, Sotirios Tsimikas, Valentı́n Fuster, Sam Gandy, Robert O. Bonow, Olga Gursky, Jagat Narula	2023	18
8	Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug–Gene Networks: From Biology to Precision Therapeutics Circulation ·Julius L. Decano, Enrico Maiorino, Joan T. Matamalas, Sarvesh Chelvanambi, J.M. Marugán, Jyun-Ji Wang, Kuan Wee-Ling, Prabhash Kumar Jha, 基彰青木, Lindsay Kelly, Mary C. Whelan, Ge Rile, 実宮川, Amitabh Sharma, Peter Libby, Sasha A. Singh, Elena Aïkawa, Masanori Aikawa	2023	15
9	Network-Guided Multiomic Mapping of Aortic Valve Calcification Arteriosclerosis Thrombosis and Vascular Biology ·Mark C. Blaser, Simon Kraler, Thomas F. Lüscher, Elena Aïkawa	2023	10
10	Progression of aortic stenosis after an acute myocardial infarction Open Heart ·Mikhail V. Yaroslavtsev, César Andrés Barragán Silva, John A. Bomankiewicz, 宋长海, Maurice J. Peterson, Т В Чекушина, Donald B. Carter, Elena Aïkawa, Robert A. Levine, Philippe Pîbarot, Marie‐Annick Clavel, Jonathan Beaudoin	2022	4
11	Circulating Extracellular Vesicles As Biomarkers and Drug Delivery Vehicles in Cardiovascular Diseases Biomolecules ·Renata Caroline Costa de Freitas, Rosário Dominguez Crespo Hirata, Mário Hiroyuki Hirata, Elena Aïkawa	2021	41
12	Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion Cardiovascular Research ·Maximillian A. Rogers, Joshua D. Hutcheson, C. Kevers, Claudia Goettsch, Sasha A. Singh, Arda Halu, Florian Schlotter, Hideyuki Higashi, Lixiang Wang, Mary C. Whelan, Eriberto de Sá Ponte, Alan Daugherty, Masatoshi Nomura, Masanori Aikawa, Elena Aïkawa	2021	21
13	What Makes a Great Mentor: Interviews With Recipients of the ATVB Mentor of Women Award Arteriosclerosis Thrombosis and Vascular Biology ·Hanrui Zhang, Zhen Chen, Gabrielle Fredman, Delphine Gomez, Isabella M. Grumbach, Ngan F. Huang, Patricia K. Nguyen, Mireille Ouimet, Nadia R. Sutton, Elena Aïkawa	2021	2
14	Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy European Heart Journal ·Simon Kraler, Mark C. Blaser, Elena Aïkawa, Giovanni G. Camici, Thomas F. Lüscher	2021	128
15	Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development Circulation ·Julius L. Decano, Sasha A. Singh, R.B. Lackey, Lang Ho Lee, Arda Halu, Sarvesh Chelvanambi, Joan T. Matamalas, Hengmin Zhang, Eriberto de Sá Ponte, Jiao Qiao, Amitabh Sharma, Shin Mukai, Jianguo Wang, Daniel G. Anderson, C. Keith Ozaki, Peter Libby, Elena Aïkawa, Masanori Aikawa	2021	21
16	Aortic valve calcification predicts all-cause mortality independent of coronary calcification and severe stenosis Atherosclerosis ·Jared Christensen, R. Vialle, Xiao-Dong, Siska Silviana Rizki, 邓超, Ana Clara Zalasik, Ma Helena Rosales, M. А. Умирзакова, Nishant R. Shah, Wen‐Chih Wu, Hyung J. Chun, Elena Aïkawa, Gaurav Choudhary, Alan Morrison	2020	26
17	Valvular interstitial cells suppress calcification of valvular endothelial cells Atherosclerosis ·Jesper Hjortnaes, Kayle Shapero, Claudia Goettsch, Joshua D. Hutcheson, Joshua Keegan, Jolanda Kluin, John E. Mayer, Joyce Bischoff, Elena Aïkawa	2015	144
18	Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata European Heart Journal ·Chad E. Brokopp, Roman Schoenauer, Peter J. Richards, Stefan Bauer, Christine Lohmann, Maximilian Y. Emmert, Benedikt Weber, Stephan Winnik, Elena Aïkawa, Kirk Graves, Michele Genoni, Peter Vogt, Thomas F. Lüscher, Christoph Renner, Simon P. Hoerstrup, Christian M. Matter	2011	127
19	Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites Science ·Filip K. Świrski, Matthias Nahrendorf, Martin Etzrodt, Moritz Wildgruber, Virna Cortez‐Retamozo, Peter Panizzi, Jose‐Luiz Figueiredo, Rainer H. Köhler, Aleksey Chudnovskiy, Peter Waterman, Elena Aïkawa, Thorsten R. Mempel, Peter Libby, Ralph Weissleder, Mikäel J. Pittet Hit paper breakdown →	2009	1708
20	The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions The Journal of Experimental Medicine ·Matthias Nahrendorf, Filip K. Świrski, Elena Aïkawa, Lars Stangenberg, Thomas Würdinger, Jose‐Luiz Figueiredo, Peter Libby, Ralph Weissleder, Mikäel J. Pittet Hit paper breakdown →	2007	1769

About Elena Aïkawa

Elena Aïkawa is a scholar working on Cardiology and Cardiovascular Medicine, Immunology and Allergy, Nephrology, Cancer Research and Immunology, having authored 261 papers that have together received 22.1k indexed citations. Recurring topics across this work include Cardiac Valve Diseases and Treatments (81 papers), Aortic Disease and Treatment Approaches (33 papers), Atherosclerosis and Cardiovascular Diseases (28 papers), Infective Endocarditis Diagnosis and Management (26 papers), Protease and Inhibitor Mechanisms (19 papers), Parathyroid Disorders and Treatments (19 papers), Cell Adhesion Molecules Research (18 papers) and Cardiac Imaging and Diagnostics (17 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (7.4k citations), Immunology (5.2k citations), Nephrology (1.2k citations), Immunology and Allergy (1.0k citations) and Cancer Research (2.4k citations). Elena Aïkawa has collaborated with scholars based in United States, Netherlands and United Kingdom. Frequent co-authors include Ralph Weissleder, Peter Libby, Filip K. Świrski, Matthias Nahrendorf, Masanori Aikawa, Mikäel J. Pittet, Jose‐Luiz Figueiredo, Joshua D. Hutcheson, Farouc A. Jaffer and Sophie E. P. New. Their work appears in journals such as Circulation, Arteriosclerosis Thrombosis and Vascular Biology, Frontiers in Cardiovascular Medicine, Circulation Research and European Heart Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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