Douglas L. Brutlag

11.7k total citations · 6 hit papers
98 papers, 9.2k citations indexed

About

Douglas L. Brutlag is a scholar working on Molecular Biology, Materials Chemistry and Genetics. According to data from OpenAlex, Douglas L. Brutlag has authored 98 papers receiving a total of 9.2k indexed citations (citations by other indexed papers that have themselves been cited), including 87 papers in Molecular Biology, 13 papers in Materials Chemistry and 10 papers in Genetics. Recurrent topics in Douglas L. Brutlag's work include DNA and Nucleic Acid Chemistry (24 papers), RNA and protein synthesis mechanisms (23 papers) and Protein Structure and Dynamics (22 papers). Douglas L. Brutlag is often cited by papers focused on DNA and Nucleic Acid Chemistry (24 papers), RNA and protein synthesis mechanisms (23 papers) and Protein Structure and Dynamics (22 papers). Douglas L. Brutlag collaborates with scholars based in United States, Australia and Poland. Douglas L. Brutlag's co-authors include Arthur Kornberg, Jun S. Liu, Paul Berg, Serge Saxonov, X. Liu, Tao‐shih Hsieh, Earl R. Shelton, X. Shirley Liu, Randy Schekman and Neil Osheroff and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Douglas L. Brutlag

98 papers receiving 8.5k citations

Hit Papers

A genome-wide analysis of CpG ... 1971 2026 1989 2007 2006 2000 2002 1972 1972 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
    2006 961 citations Douglas L. Brutlag et al. Proceedings of the National Academy of Sciences profile →
  2. BIOPROSPECTOR: DISCOVERING CONSERVED DNA MOTIFS IN UPSTREAM REGULATORY REGIONS OF CO-EXPRESSED GENES
    2000 608 citations X. Liu, Douglas L. Brutlag et al. PubMed profile →
  3. An algorithm for finding protein–DNA binding sites with applications to chromatin- immunoprecipitation microarray experiments
    2002 514 citations Douglas L. Brutlag, Jun S. Liu et al. profile →
  4. Enzymatic Synthesis of Deoxyribonucleic Acid
    1972 509 citations Douglas L. Brutlag, Arthur Kornberg Journal of Biological Chemistry profile →
  5. RNA Synthesis Initiates In Vitro Conversion of M13 DNA to Its Replicative Form
    1972 249 citations Douglas L. Brutlag, Arthur Kornberg et al. Proceedings of the National Academy of Sciences profile →
  6. A Possible Role for RNA Polymerase in the Initiation of M13 DNA Synthesis
    1971 217 citations Douglas L. Brutlag, Arthur Kornberg et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Douglas L. Brutlag United States 46 7.7k 1.8k 1.4k 700 427 98 9.2k
John C. Wootton United Kingdom 42 6.0k 0.8× 1.3k 0.7× 1.2k 0.9× 531 0.8× 451 1.1× 83 10.9k
Hans‐Werner Mewes Germany 44 11.2k 1.5× 1.3k 0.7× 1.7k 1.2× 421 0.6× 432 1.0× 124 13.9k
Thomas D. Schneider United States 35 7.1k 0.9× 2.7k 1.5× 721 0.5× 1.1k 1.6× 226 0.5× 63 8.7k
Jorja G. Henikoff United States 40 10.8k 1.4× 1.5k 0.8× 2.7k 2.0× 374 0.5× 558 1.3× 54 13.2k
Michael Gribskov United States 42 7.4k 1.0× 1.5k 0.8× 3.6k 2.6× 699 1.0× 311 0.7× 94 10.9k
Mark Schena United States 21 9.1k 1.2× 1.4k 0.8× 1.7k 1.2× 353 0.5× 231 0.5× 26 11.8k
Gianni Cesareni Italy 59 11.4k 1.5× 1.5k 0.8× 717 0.5× 707 1.0× 208 0.5× 188 13.9k
Ioannis Xénarios Switzerland 52 10.3k 1.3× 1.2k 0.7× 2.0k 1.4× 671 1.0× 371 0.9× 171 14.3k
Olivier Poch France 50 7.6k 1.0× 1.7k 0.9× 1.0k 0.7× 668 1.0× 408 1.0× 174 10.7k
Ying Xu United States 45 6.1k 0.8× 815 0.5× 1.1k 0.8× 1.1k 1.5× 286 0.7× 263 8.5k

Countries citing papers authored by Douglas L. Brutlag

Since Specialization
Citations

This map shows the geographic impact of Douglas L. Brutlag's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas L. Brutlag with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas L. Brutlag more than expected).

Fields of papers citing papers by Douglas L. Brutlag

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas L. Brutlag. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas L. Brutlag. The network helps show where Douglas L. Brutlag may publish in the future.

Co-authorship network of co-authors of Douglas L. Brutlag

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas L. Brutlag. A scholar is included among the top collaborators of Douglas L. Brutlag based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas L. Brutlag. Douglas L. Brutlag is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Spagnolo, Jeannie F., et al.. (2006). Nucleotide Channel of RNA-dependent RNA Polymerase used for Intermolecular Uridylylation of Protein Primer. Journal of Molecular Biology. 357(2). 665–675. 25 indexed citations
2.
Huang, Xiaoqiu & Douglas L. Brutlag. (2006). Dynamic use of multiple parameter sets in sequence alignment. Nucleic Acids Research. 35(2). 678–686. 19 indexed citations
3.
Wang, Haidong, Eran Segal, Asa Ben‐Hur, Daphne Koller, & Douglas L. Brutlag. (2004). Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale. Neural Information Processing Systems. 17. 1465–1472. 14 indexed citations
4.
Brutlag, Douglas L., et al.. (2004). FoldMiner and LOCK 2: protein structure comparison and motif discovery on the web. Nucleic Acids Research. 32(Web Server). W536–W541. 28 indexed citations
5.
Apaydın, Mehmet Serkan, Carlos Guestrin, Chris Varma, Douglas L. Brutlag, & Jean‐Claude Latombe. (2002). Stochastic roadmap simulation for the study ofligand-protein interactions. Bioinformatics. 18(suppl_2). S18–S26. 25 indexed citations
6.
Brutlag, Douglas L., et al.. (2002). Using robotics to fold proteins and dock ligands. Bioinformatics. 18(suppl_2). S74–S74. 8 indexed citations
7.
Liu, X., Douglas L. Brutlag, & Jun S. Liu. (2000). BIOPROSPECTOR: DISCOVERING CONSERVED DNA MOTIFS IN UPSTREAM REGULATORY REGIONS OF CO-EXPRESSED GENES. PubMed. 127–138. 608 indexed citations breakdown →
8.
Lengauer, Thomas, Reinhard Schneider, Peer Bork, et al.. (1999). Proceedings of the Seventh International Conference on Intelligent Systems for Molecular Biology. 95 indexed citations
9.
Rindfleisch, Thomas C. & Douglas L. Brutlag. (1998). Directions for Clinical Research and Genomic Research into the Next Decade: Implications for Informatics. Journal of the American Medical Informatics Association. 5(5). 404–411. 13 indexed citations
10.
Brutlag, Douglas L.. (1998). Genomics and computational molecular biology. Current Opinion in Microbiology. 1(3). 340–345. 15 indexed citations
11.
Tomita, Motowo, Nobutaka Shimizu, & Douglas L. Brutlag. (1996). Introns and reading frames: correlation between splicing sites and their codon positions. Molecular Biology and Evolution. 13(9). 1219–1223. 45 indexed citations
12.
Galper, Adam, et al.. (1993). Knowledge-based simulation of DNA metabolism: Prediction of action and envisionment of pathways. 365–395. 7 indexed citations
13.
Brutlag, Douglas L., et al.. (1989). Is there a relationship between DNA sequences encoding peptide ligands and their receptors?. Proceedings of the National Academy of Sciences. 86(1). 42–45. 22 indexed citations
14.
Fairman, Robert & Douglas L. Brutlag. (1988). Expression of the Drosophila type II topoisomerase is developmentally regulated. Biochemistry. 27(2). 560–565. 40 indexed citations
15.
Lohe, Allan R. & Douglas L. Brutlag. (1987). Identical satellite DNA sequences in sibling species of Drosophila. Journal of Molecular Biology. 194(2). 161–170. 62 indexed citations
16.
Friedland, Peter, et al.. (1982). GENESIS, a knowledge-based genetic engineering simulation system for represntation of genetic data and experiment planning. Nucleic Acids Research. 10(1). 323–340. 16 indexed citations
17.
Germond, Jacques‐Edouard, Josette Rouvière‐Yaniv, Moshé Yaniv, & Douglas L. Brutlag. (1979). Nicking-closing enzyme assembles nucleosome-like structures in vitro.. Proceedings of the National Academy of Sciences. 76(8). 3779–3783. 75 indexed citations
18.
Westergaard, Ole, Douglas L. Brutlag, & Arthur Kornberg. (1973). Initiation of Deoxyribonucleic Acid Synthesis. Journal of Biological Chemistry. 248(4). 1361–1364. 62 indexed citations
19.
Brutlag, Douglas L., et al.. (1969). Properties of formaldehyde-treated nucleohistone. Biochemistry. 8(8). 3214–3218. 164 indexed citations
20.
Brutlag, Douglas L., et al.. (1969). An active fragment of DNA polymerase produced by proteolytic cleavage. Biochemical and Biophysical Research Communications. 37(6). 982–989. 166 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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