Derek M. Dykxhoorn

13.2k total citations · 6 hit papers
103 papers, 9.9k citations indexed

About

Derek M. Dykxhoorn is a scholar working on Molecular Biology, Genetics and Cancer Research. According to data from OpenAlex, Derek M. Dykxhoorn has authored 103 papers receiving a total of 9.9k indexed citations (citations by other indexed papers that have themselves been cited), including 80 papers in Molecular Biology, 25 papers in Genetics and 20 papers in Cancer Research. Recurrent topics in Derek M. Dykxhoorn's work include RNA Interference and Gene Delivery (22 papers), MicroRNA in disease regulation (20 papers) and CRISPR and Genetic Engineering (12 papers). Derek M. Dykxhoorn is often cited by papers focused on RNA Interference and Gene Delivery (22 papers), MicroRNA in disease regulation (20 papers) and CRISPR and Genetic Engineering (12 papers). Derek M. Dykxhoorn collaborates with scholars based in United States, Canada and China. Derek M. Dykxhoorn's co-authors include Judy Lieberman, Carl D. Novina, Phillip A. Sharp, Deborah Palliser, Nan Yan, Sang‐Kyung Lee, Premlata Shankar, Dipanjan Chowdhury, Yair Benita and Alan Engelman and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Derek M. Dykxhoorn

97 papers receiving 9.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

2008 1.1k citations Abraham L. Brass, Derek M. Dykxhoorn et al. Science profile →
Lentivirus-delivered stable gene silencing by RNAi in primary cells

2003 1.1k citations Derek M. Dykxhoorn, Phillip A. Sharp et al. profile →
Killing the messenger: short RNAs that silence gene expression

2003 918 citations Derek M. Dykxhoorn, Carl D. Novina et al. Nature Reviews Molecular Cell Biology profile →
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

2005 808 citations Derek M. Dykxhoorn, Judy Lieberman et al. profile →
siRNA-directed inhibition of HIV-1 infection

2002 631 citations Carl D. Novina, Derek M. Dykxhoorn et al. profile →
Breaking down the barriers: siRNA delivery and endosome escape

2010 514 citations Derek M. Dykxhoorn et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Derek M. Dykxhoorn United States	36	7.6k	2.3k	1.4k	1.2k	1.1k	103	9.9k
Sayda M. Elbashir United States	16	12.4k 1.6×	2.7k 1.2×	2.1k 1.5×	1.3k 1.1×	219 0.2×	26	14.2k
Premlata Shankar United States	35	4.9k 0.6×	1.2k 0.5×	1.2k 0.8×	2.3k 1.9×	1.4k 1.3×	68	7.6k
Daniel Ory United States	39	5.4k 0.7×	711 0.3×	2.9k 2.0×	893 0.7×	747 0.7×	110	10.4k
Marco Rusnati Italy	55	5.8k 0.8×	1.1k 0.5×	660 0.5×	1.7k 1.4×	767 0.7×	174	9.0k
Tae‐Young Roh South Korea	34	11.9k 1.6×	1.7k 0.7×	1.7k 1.2×	2.4k 1.9×	225 0.2×	83	14.8k
Carl D. Novina United States	37	5.5k 0.7×	1.8k 0.8×	858 0.6×	1.0k 0.8×	279 0.3×	65	7.2k
Michael J. Gait United Kingdom	64	10.7k 1.4×	721 0.3×	1.3k 0.9×	639 0.5×	1.4k 1.3×	229	12.3k
António Bernad Spain	43	5.5k 0.7×	1.7k 0.7×	1.2k 0.9×	936 0.8×	169 0.2×	115	8.2k
Kevin V. Morris United States	44	7.3k 1.0×	4.1k 1.8×	841 0.6×	659 0.5×	539 0.5×	131	8.7k
Elisa Izaurralde Germany	89	22.9k 3.0×	5.8k 2.5×	1.4k 1.0×	1.4k 1.2×	473 0.4×	163	25.6k

Countries citing papers authored by Derek M. Dykxhoorn

Since Specialization

Citations

This map shows the geographic impact of Derek M. Dykxhoorn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Derek M. Dykxhoorn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Derek M. Dykxhoorn more than expected).

Fields of papers citing papers by Derek M. Dykxhoorn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Derek M. Dykxhoorn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Derek M. Dykxhoorn. The network helps show where Derek M. Dykxhoorn may publish in the future.

Co-authorship network of co-authors of Derek M. Dykxhoorn

This figure shows the co-authorship network connecting the top 25 collaborators of Derek M. Dykxhoorn. A scholar is included among the top collaborators of Derek M. Dykxhoorn based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Derek M. Dykxhoorn. Derek M. Dykxhoorn is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Eldstrom, Jodene, Alicia de la Cruz, Maykelis Dı́az, et al.. (2025). The conductance of KCNQ2 and its pathogenic variants is determined by individual subunit gating. Science Advances. 11(10). eadr7012–eadr7012.

Cruz, Alicia de la, et al.. (2024). Lipophilic compounds restore function to neurodevelopmental-associated KCNQ3 mutations. Communications Biology. 7(1). 1181–1181. 1 indexed citations

Dykxhoorn, Derek M., et al.. (2023). MicroRNA-423-5p Mediates Cocaine-Induced Smooth Muscle Cell Contraction by Targeting Cacna2d2. International Journal of Molecular Sciences. 24(7). 6584–6584. 4 indexed citations

Tao, Yazhong, Derek M. Dykxhoorn, Felicia Ruffin, et al.. (2023). 307. Exploring HLA genotypes as contributing risk factors in Staphylococcus aureus bacteremia. Open Forum Infectious Diseases. 10(Supplement_2). 1 indexed citations

Ferreira, Andrea da Fonseca, Jianqin Wei, Conrad Macon, et al.. (2023). HIV Promotes Atherosclerosis via Circulating Extracellular Vesicle MicroRNAs. International Journal of Molecular Sciences. 24(8). 7567–7567. 6 indexed citations

Osborne, Olivia, et al.. (2023). Anti-amyloid: An antibody to cure Alzheimer’s or an attitude. iScience. 26(8). 107461–107461. 14 indexed citations

Cukier, Holly N., Anthony J. Griswold, Simona G. Codreanu, et al.. (2022). Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions. npj Parkinson s Disease. 8(1). 84–84. 6 indexed citations

Nourbakhsh, Aida, Eric S. Nisenbaum, A. Amraoui, et al.. (2021). Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art. Journal of the Association for Research in Otolaryngology. 22(2). 95–105. 20 indexed citations

Nourbakhsh, Aida, et al.. (2021). Characterization of UMi031-A-2 inducible pluripotent stem cell line with a neurofibromatosis type 2-associated mutation. Stem Cell Research. 55. 102474–102474. 2 indexed citations

10.

Lang, Anna L., Geoffrey W. Stone, Suresh Pallikkuth, et al.. (2019). HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells. PLoS Pathogens. 15(7). e1007883–e1007883. 34 indexed citations

11.

Cyr, Derek D., Andrew S. Allen, Felicia Ruffin, et al.. (2017). Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping. Genes and Immunity. 18(2). 95–99. 23 indexed citations

12.

Hokayem, Jimmy El, Holly N. Cukier, & Derek M. Dykxhoorn. (2016). Blood Derived Induced Pluripotent Stem Cells (iPSCs): Benefits, Challenges and the Road Ahead. Journal of Alzheimer’s Disease & Parkinsonism. 6(5). 19 indexed citations

13.

Ramishetti, Srinivas, Ranit Kedmi, Meir Goldsmith, et al.. (2015). Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles. ACS Nano. 9(7). 6706–6716. 160 indexed citations

14.

Dykxhoorn, Derek M., et al.. (2014). Target silencing of components of the conserved oligomeric Golgi complex impairs HIV-1 replication. Virus Research. 192. 92–102. 12 indexed citations

15.

Brass, Abraham L., Derek M. Dykxhoorn, Yair Benita, et al.. (2008). Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen. Science. 319(5865). 921–926. 1149 indexed citations breakdown →

16.

Dykxhoorn, Derek M.. (2007). MicroRNAs in Viral Replication and Pathogenesis. DNA and Cell Biology. 26(4). 239–249. 21 indexed citations

17.

Brass, Abraham L., Derek M. Dykxhoorn, & Yvonne Benito. (2007). Identification of host proteins required for HIV infection through a functional genomic screen. 20(10). 412–413. 1 indexed citations

18.

Glodek, Aleksandra M., Yi Le, Derek M. Dykxhoorn, et al.. (2007). Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells. Leukemia. 21(8). 1723–1732. 53 indexed citations

19.

Dykxhoorn, Derek M. & Judy Lieberman. (2006). Silencing Viral Infection. PLoS Medicine. 3(7). e242–e242. 40 indexed citations

20.

Dykxhoorn, Derek M., Carl D. Novina, & Phillip A. Sharp. (2003). Killing the messenger: short RNAs that silence gene expression. Nature Reviews Molecular Cell Biology. 4(6). 457–467. 918 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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