De‐En Hu

5.6k total citations · 2 hit papers
60 papers, 4.5k citations indexed

About

De‐En Hu is a scholar working on Spectroscopy, Molecular Biology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, De‐En Hu has authored 60 papers receiving a total of 4.5k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Spectroscopy, 23 papers in Molecular Biology and 22 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in De‐En Hu's work include Advanced NMR Techniques and Applications (24 papers), Advanced MRI Techniques and Applications (18 papers) and Electron Spin Resonance Studies (12 papers). De‐En Hu is often cited by papers focused on Advanced NMR Techniques and Applications (24 papers), Advanced MRI Techniques and Applications (18 papers) and Electron Spin Resonance Studies (12 papers). De‐En Hu collaborates with scholars based in United Kingdom, South Sudan and Italy. De‐En Hu's co-authors include Kevin M. Brindle, Mikko I. Kettunen, Ferdia A. Gallagher, Mathilde H. Lerche, Sam E. Day, Jan Henrik Ardenkjær‐Larsen, Klaes Golman, Brett W. C. Kennedy, Sarah E. Bohndiek and Magnus Karlsson and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

De‐En Hu

60 papers receiving 4.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

2007 733 citations Sam E. Day, Mikko I. Kettunen et al. profile →
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

2008 704 citations Ferdia A. Gallagher, Mikko I. Kettunen et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
De‐En Hu United Kingdom	34	2.1k	1.7k	1.2k	989	862	60	4.5k
Kayvan R. Keshari United States	34	1.8k 0.9×	1.4k 0.8×	1.1k 0.9×	726 0.7×	656 0.8×	93	3.8k
Ferdia A. Gallagher United Kingdom	39	2.7k 1.3×	3.1k 1.8×	833 0.7×	1.2k 1.2×	1.1k 1.2×	139	6.0k
Matthew E. Merritt United States	37	1.9k 0.9×	1.5k 0.9×	1.4k 1.2×	1.6k 1.6×	1.0k 1.2×	143	5.2k
Robert Bok United States	44	3.7k 1.8×	3.0k 1.7×	900 0.7×	1.2k 1.2×	1.2k 1.4×	129	5.9k
Mikko I. Kettunen Finland	46	3.1k 1.5×	3.1k 1.8×	2.4k 1.9×	1.6k 1.6×	1.4k 1.6×	119	8.2k
Sarah J. Nelson United States	35	2.6k 1.3×	2.6k 1.5×	635 0.5×	771 0.8×	901 1.0×	58	4.0k
Jerry D. Glickson United States	46	1.4k 0.7×	2.8k 1.6×	3.3k 2.7×	1.1k 1.1×	697 0.8×	235	7.7k
Sabrina M. Ronen United States	40	1.2k 0.6×	1.7k 1.0×	2.4k 2.0×	414 0.4×	359 0.4×	99	5.0k
Pratip K. Bhattacharya United States	26	1.7k 0.8×	589 0.3×	653 0.5×	1.0k 1.0×	444 0.5×	75	2.9k
Christian T. Farrar United States	32	445 0.2×	1.2k 0.7×	1.1k 0.9×	1.5k 1.5×	473 0.5×	73	4.1k

Countries citing papers authored by De‐En Hu

Since Specialization

Citations

This map shows the geographic impact of De‐En Hu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by De‐En Hu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites De‐En Hu more than expected).

Fields of papers citing papers by De‐En Hu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by De‐En Hu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by De‐En Hu. The network helps show where De‐En Hu may publish in the future.

Co-authorship network of co-authors of De‐En Hu

This figure shows the co-authorship network connecting the top 25 collaborators of De‐En Hu. A scholar is included among the top collaborators of De‐En Hu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with De‐En Hu. De‐En Hu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hesketh, Richard L., Jiazheng Wang, Alan J. Wright, et al.. (2019). Magnetic Resonance Imaging Is More Sensitive Than PET for Detecting Treatment-Induced Cell Death–Dependent Changes in Glycolysis. Cancer Research. 79(14). 3557–3569. 31 indexed citations

Serrão, Eva, Mikko I. Kettunen, Tiago B. Rodrigues, et al.. (2018). Analysis of ¹³C and ¹⁴C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with ¹³C‐ and ¹⁴C‐labeled pyruvate. NMR in Biomedicine. 31(5). e3901–e3901. 21 indexed citations

Mair, Richard, Alan J. Wright, Susana R�os, et al.. (2018). Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma. Cancer Research. 78(18). 5408–5418. 33 indexed citations

Xie, Bangwen, Michal R. Tomaszewski, André Neves, et al.. (2017). Optoacoustic Detection of Early Therapy-Induced Tumor Cell Death Using a Targeted Imaging Agent. Clinical Cancer Research. 23(22). 6893–6903. 24 indexed citations

Wang, Jiazheng, Alan J. Wright, Richard L. Hesketh, De‐En Hu, & Kevin M. Brindle. (2017). A referenceless Nyquist ghost correction workflow for echo planar imaging of hyperpolarized [1‐¹³C]pyruvate and [1‐¹³C]lactate. NMR in Biomedicine. 31(2). 11 indexed citations

Timm, Kerstin N., De‐En Hu, Michael J. Williams, et al.. (2016). Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy. Journal of Biological Chemistry. 292(5). 1737–1748. 28 indexed citations

Gallagher, Ferdia A., Mikko I. Kettunen, Eva Serrão, et al.. (2015). Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors. Cancer Research. 75(19). 4109–4118. 36 indexed citations

Brindle, Kevin M., De‐En Hu, Tiago B. Rodrigues, Eva Serrão, & Kerstin N. Timm. (2014). 17: Magnetic resonance imaging of tumour metabolism. European Journal of Cancer. 50. S5–S6. 1 indexed citations

Kettunen, Mikko I., Brett W. C. Kennedy, De‐En Hu, & Kevin M. Brindle. (2012). Spin echo measurements of the extravasation and tumor cell uptake of hyperpolarized [1‐¹³C]lactate and [1‐¹³C]pyruvate. Magnetic Resonance in Medicine. 70(5). 1200–1209. 42 indexed citations

10.

Bohndiek, Sarah E., Mikko I. Kettunen, De‐En Hu, et al.. (2011). Hyperpolarized [1-¹³C]-Ascorbic and Dehydroascorbic Acid: Vitamin C as a Probe for Imaging Redox Status in Vivo. Journal of the American Chemical Society. 133(30). 11795–11801. 152 indexed citations

11.

Woodfin, Abigail, De‐En Hu, Mosharraf H. Sarker, Tsuyoshi Kurokawa, & Paul Fraser. (2010). Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia–reperfusion. Free Radical Biology and Medicine. 50(4). 518–524. 22 indexed citations

12.

Gallagher, Ferdia A., Mikko I. Kettunen, Sam E. Day, et al.. (2008). Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate. Nature. 453(7197). 940–943. 704 indexed citations breakdown →

13.

Bundy, Jacob G., N. Gopalakrishna Iyer, Michelle Gentile, et al.. (2006). Metabolic Consequences of p300 Gene Deletion in Human Colon Cancer Cells. Cancer Research. 66(15). 7606–7614. 23 indexed citations

14.

Hu, De‐En, Alexander S. Easton, & Paul Fraser. (2005). TRPV1 activation results in disruption of the blood–brain barrier in the rat. British Journal of Pharmacology. 146(4). 576–584. 45 indexed citations

15.

Hu, De‐En & Kevin M. Brindle. (2005). Immune cell‐induced synthesis of NO and reactive oxygen species in lymphoma cells causes their death by apoptosis. FEBS Letters. 579(13). 2833–2841. 18 indexed citations

16.

Hu, De‐En & Tai-Ping Fan. (1995). Suppression of VEGF‐induced angiogenesis by the protein tyrosine kinase inhibitor, lavendustin A. British Journal of Pharmacology. 114(2). 262–268. 57 indexed citations

17.

Hu, De‐En & Tai‐Ping Fan. (1995). Protein kinase C inhibitor calphostin C prevents cytokine-induced angiogenesis in the rat. Inflammation. 19(1). 39–54. 19 indexed citations

18.

Hu, De‐En, et al.. (1995). Correlation of 133Xe clearance, blood flow and histology in the rat sponge model for angiogenesis. Further studies with angiogenic modifiers.. PubMed. 72(5). 601–10. 50 indexed citations

19.

Fan, Tai‐Ping D., et al.. (1992). Further studies on angiogenesis in a rat sponge model. Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions. 61. 308–314. 4 indexed citations

20.

Honess, Davina J., De‐En Hu, & N M Bleehen. (1991). A study of the mechanism of hydralazine enhancement of thermal damage in the KHT tumour. International Journal of Hyperthermia. 7(4). 667–679. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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