Debra L. Smith

5.1k citations

15 papers · 4.1k indexed · 2 hit papers · h-index 10

Impact in

Molecular Biology top 2%
- PI3K/AKT/mTOR signaling in cancer
- Protein Kinase Regulation and GTPase Signaling
- Metabolism, Diabetes, and Cancer
Cancer Research top 5%
- Cancer, Hypoxia, and Metabolism

Papers in

Genetics 2
- Chronic Lymphocytic Leukemia Research 1
Hematology 2
- Acute Myeloid Leukemia Research 1

Co-authors: Gordon B. Mills Yiling Lu Bryan T. Hennessy Prahlad T. Ram Qing‐Bai She Kathryn O’Reilly Heidi A. Lane Neal Rosen
Journals: Advances in experimental medicine and biology (1 paper)Journal of Pediatric Hematology/Oncology (1 paper)Nature Reviews Drug Discovery (1 paper)Journal of Clinical Oncology (1 paper)Seminars in Oncology (1 paper)
Partner nations: United States Canada Austria

In The Last Decade

Debra L. Smith

14 papers receiving 4.0k citations

Hit Papers

align trajectories log scale

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt 2006 · 2.0k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2006 Cancer Research
2005 Nature Reviews Drug Discovery

Peers

Countries citing papers authored by Debra L. Smith

Since Specialization

Citations

This map shows the geographic impact of Debra L. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Debra L. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Debra L. Smith more than expected).

Fields of papers citing papers by Debra L. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Debra L. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Debra L. Smith. The network helps show where Debra L. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Debra L. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Debra L. Smith Line = papers co-authored together Debra L. Smith links everyone, so they are left out of the graph.

All Works

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15 of 15 papers shown

#	Work
1	Perioperative anaemia management Annals of Blood ·Saikat Mandal, Debra L. Smith, Yudy Mariet Muñoz Motta, Vernon Louw, Е.А. Покушалов, K Mrch x, Vitória C. Lima, Daria Akhbari	2023	1
2	Characterization of theHBB: c.233G > C Variant: No Evidence of aβ-Thalassemic Phenotype Hemoglobin* ·Debra L. Smith, Midori Mitui, Jason Y. Park, Hung S. Luu, Charles F. Timmons	2015	1
3	REAL3: A multicenter randomized phase II/III trial of epirubicin, oxaliplatin, and capecitabine (EOC) versus modified (m) EOC plus panitumumab (P) in advanced oesophagogastric (OG) cancer—Response rate (RR), toxicity, and molecular analysis from phase II. Journal of Clinical Oncology ·Ian Chau, Alicia Okines, David González de Castro, Claire Saffery, Yolanda Barbáchano, Andrew Wotherspoon, L. Puckey, Sanna Hulkki Wilson, Fareeda Y. Coxon, Gary Middleton, D. Ferry, T. Crosby, Srinivasan Madhusudan, Jonathan Wadsley, Justin S. Waters, Marcia Hall, Daniel Swinson, Angus Robinson, Debra L. Smith, David Cunningham	2011	9
4	GSK3 Mediates Signaling Upstream of Akt Digital Commons-TMC (Texas Medical Center) ·Debra L. Smith	2010	0
5	Homozygous deletion of glycogen synthase kinase 3β bypasses senescence allowing Ras transformation of primary murine fibroblasts Proceedings of the National Academy of Sciences ·Shuying Liu, Xianjun Fang, Hassan Hall, Shuangxing Yu, Debra L. Smith, Zhimin Lu, Dexing Fang, Jinsong Liu, L. Clifton Stephens, James R. Woodgett, Gordon B. Mills	2008	17
6	Individualized Molecular Medicine: Linking Functional Proteomics to Select Therapeutics Targeting the PI3K Pathway for Specific Patients Advances in experimental medicine and biology ·Mandi M. Murph, Debra L. Smith, Bryan T. Hennessy, Yiling Lu, Corwin Joy, Kevin R. Coombes, Gordon B. Mills	2008	6
7	mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt Cancer Research ·Kathryn O’Reilly, 李欣广, Qing‐Bai She, David B. Solit, Gordon B. Mills, Debra L. Smith, Heidi A. Lane, Francesco Hofmann, Daniel J. Hicklin, Dale L. Ludwig, José Baselga, Neal Rosen Hit paper breakdown →	2006	2037
8	Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery Nature Reviews Drug Discovery ·Bryan T. Hennessy, Debra L. Smith, Prahlad T. Ram, Yiling Lu, Gordon B. Mills Hit paper breakdown →	2005	1750
9	Molecular therapeutics: promise and challenges Seminars in Oncology ·Elise C. Kohn, Yiling Lu, Hongwei Wang, Qinghua Yu, Shuangxing Yu, Hassan Hall, Debra L. Smith, Funda Meric‐Bernstam, Gabriel N. Hortobágyi, Gordon B. Mills	2004	17
10	Spread of Exotic Cordgrasses and Hybrids (Spartina sp.) in the Tidal Marshes of San Francisco Bay, California, USA Biological Invasions ·Debra R. Ayres, Debra L. Smith, Vanessa Brasil Campos, Marta Mozes, Donald R. Strong	2004	178
11	Practical Management of Combined Methylmalonicaciduria and Homocystinuria Journal of Child Neurology ·Debra L. Smith, Olaf A. Bodamer	2002	12
12	A Phase I trial of bryostatin-1 in children with refractory solid tumors: a Pediatric Oncology Group study. PubMed ·Steven Weitman, Anne‐Marie Langevin, Roger L. Berkow, Paul J. Thomas, Craig A. Hurwitz, Andrew S. Kraft, Ronald L. Dubowy, Debra L. Smith, Mark L. Bernstein	1999	34
13	Lipoblastoma Presenting as a Mesenteric Mass in an Infant Journal of Pediatric Hematology/Oncology ·Iryna Oleksandrivna Dudchenko, Anca Trandafir, Diane L. Persons, Saeed Ally, Debra L. Smith, Cooley G. Pantazis, Stephen Smith	1998	15
14	The Posttranslational Processing of β‐Endorphin in Human Hypothalamus Journal of Neurochemistry ·William R. Millington, Debra L. Smith	1991	10
15	Sensation seeking and arousal: Effects of strong stimulation of electrodermal activation and memory task performance Personality and Individual Differences ·Barry Smith, Robyn Davidson, Debra L. Smith, Harold W. Goldstein, William M. Perlstein	1989	17

About Debra L. Smith

Debra L. Smith is a scholar working on Genetics, Hematology, Biochemistry, Clinical Biochemistry and Cancer Research, having authored 15 papers that have together received 4.1k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (3 papers), Protein Degradation and Inhibitors (2 papers), Cancer-related Molecular Pathways (2 papers), Cancer-related gene regulation (2 papers), Acute Myeloid Leukemia Research (1 paper), Visual perception and processing mechanisms (1 paper), Chronic Lymphocytic Leukemia Research (1 paper) and Testicular diseases and treatments (1 paper). The work is most often cited by research in Molecular Biology (3.0k citations), Cancer Research (574 citations), Oncology (986 citations), Genetics (356 citations) and Pathology and Forensic Medicine (530 citations). Debra L. Smith has collaborated with scholars based in United States, Canada and Austria. Frequent co-authors include Gordon B. Mills, Yiling Lu, Bryan T. Hennessy, Prahlad T. Ram, Qing‐Bai She, Kathryn O’Reilly, Heidi A. Lane, Neal Rosen, José Baselga and Dale L. Ludwig. Their work appears in journals such as Advances in experimental medicine and biology, Journal of Pediatric Hematology/Oncology, Nature Reviews Drug Discovery, Journal of Clinical Oncology and Seminars in Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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