Dean A. Handley

4.9k citations

99 papers · 3.8k indexed · 2 hit papers · h-index 31

Impact in

Hematology top 1%
- Blood Coagulation and Thrombosis Mechanisms
- Platelet Disorders and Treatments
- Hemophilia Treatment and Research
Internal Medicine top 2%
- Venous Thromboembolism Diagnosis and Management

Papers in

Hematology 22
- Blood Coagulation and Thrombosis Mechanisms 13
- Hemophilia Treatment and Research 7
Internal Medicine 5

Co-authors: Peter P. Nawroth D Stern Robert N. Saunders Charles T. Esmon Ilan Bank Leonard Chess Shu Chien Georgina M. Nemecek
Journals: Prostaglandins (4 papers)Proceedings of the National Academy of Sciences (4 papers)Thrombosis and Haemostasis (4 papers)The Lancet (3 papers)The Journal of Experimental Medicine (3 papers)
Partner nations: United States Japan United Kingdom

In The Last Decade

Dean A. Handley

97 papers receiving 3.5k citations

Hit Papers

align trajectories log scale

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity. 1986 · 492 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1986 Proceedings of the National Academy of Sciences
1986 The Journal of Experimental Medicine

Peers

Countries citing papers authored by Dean A. Handley

Since Specialization

Citations

This map shows the geographic impact of Dean A. Handley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dean A. Handley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dean A. Handley more than expected).

Fields of papers citing papers by Dean A. Handley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dean A. Handley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dean A. Handley. The network helps show where Dean A. Handley may publish in the future.

Co-authors

The 25 scholars most cited alongside Dean A. Handley, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dean A. Handley Line = papers co-authored together Dean A. Handley links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Single‐Isomer β‐Agonists Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy ·Dean A. Handley	2001	11
2	Advancement of the Third Generation of Antihistamines Pediatric Asthma Allergy & Immunology ·Dean A. Handley	1999	2
3	The asthma-like pharmacology and toxicology of (S)-isomers of β agonists Journal of Allergy and Clinical Immunology ·Dean A. Handley	1999	42
4	Sympathomimetic enantiomers and asthma Chirality ·Dean A. Handley, John R. McCullough, S. D. Crowther, John E. Morley	1998	33
5	Effect of Enantiomeric Forms of Albuterol on Stimulated Secretion of Granular Protein from Human Eosinophils Pulmonary Pharmacology & Therapeutics ·Alan R. Leff, Anja Herrnreiter, Robert M. Naclerio, Fuad M. Baroody, Dean A. Handley, N. M. Muñoz	1997	40
6	PHARMACOLOGICAL APPROACHES AND STRATEGIES FOR THERAPEUTIC MODULATION OF FIBRINOGEN Thrombosis Research ·Dean A. Handley, Thomas E. Hughes	1997	17
7	R-Albuterol Clinical Reviews in Allergy & Immunology ·Dean A. Handley	1996	2
8	Antitumor Activity of 5-Aryl-2,3-dihydroimidazo[2,1-a]isoquinolines Journal of Medicinal Chemistry ·William J. Houlihan, P. G. Munder, Dean A. Handley, Seung Hoon Cheon, Vincent A. Parrino	1995	41
9	Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists Journal of Medicinal Chemistry ·William J. Houlihan, Seung Hoon Cheon, Vincent A. Parrino, Dean A. Handley, Douglas A. Larson	1993	31
10	Platelet-activating factor in endotoxin and immune diseases Dean A. Handley	1990	27
11	Prevention of non‐specific airway hyperreactivity after allergen challenge in guinea‐pigs by the PAF receptor antagonist SDZ 64–412 British Journal of Pharmacology ·Andrew M. Havill, Ronald G. Van Valen, Dean A. Handley	1990	33
12	Preclinical and clinical pharmacology of platelet‐activating factor receptor antagonists Medicinal Research Reviews ·Dean A. Handley	1990	14
13	Terbinafine inhibits the mitogenic response to platelet-derived growth factor in vitro and neointimal proliferation in vivo. Journal of Pharmacology and Experimental Therapeutics ·Georgina M. Nemecek, I.H. St. Denny, Ronald G. Van Valen, Lily Mccarthy, Dean A. Handley, Anton Stütz	1989	9
14	Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas. The Journal of Experimental Medicine ·Peter P. Nawroth, Dean A. Handley, Gary R. Matsueda, Rob de Waal, Herwig Gerlach, Dietmar Blohm, D Stern	1988	136
15	PAF involvement in dermal extravasation in the reverse passive Arthus reaction Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) ·R.W. Deacon, Mary Kay Melden, R.N. Saunders, Dean A. Handley	1986	5
16	Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1. The Journal of Experimental Medicine ·Peter P. Nawroth, Ilan Bank, Dean A. Handley, Judy Cassimeris, Leonard Chess, D Stern Hit paper breakdown →	1986	587
17	Cellular processing of bovine factors X and Xa by cultured bovine aortic endothelial cells. The Journal of Experimental Medicine ·Peter P. Nawroth, Dennis J. McCarthy, Walter Kisiel, Dean A. Handley, D Stern	1985	25
18	Erythropoietic uroporphyria of Gunther first presenting at 58 years with positive family studies. BMJ ·Roy W. Pain, FrancisH. Welch, Andrew J. Woodroffe, Dean A. Handley, W. H. Lockwood	1975	22
19	SURGICAL TREATMENT OF DUODENAL ULCERATION IN TWO HÆMOPHILIACS The Lancet ·Dean A. Handley, Neil S. Painter, Marcia Hall	1961	12
20	SURGERY IN A PATIENT WITH AN ACQUIRED CIRCULATING ANTICOAGULANT The Lancet ·Harold Ellis, Dean A. Handley, K. B. Taylor	1959	19

About Dean A. Handley

Dean A. Handley is a scholar working on Hematology, Internal Medicine, Immunology and Allergy, Genetics and Animal Science and Zoology, having authored 99 papers that have together received 3.8k indexed citations. Recurring topics across this work include Asthma and respiratory diseases (14 papers), Blood Coagulation and Thrombosis Mechanisms (13 papers), Pharmacological Effects and Assays (9 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (8 papers), Blood properties and coagulation (8 papers), Hemophilia Treatment and Research (7 papers), Protease and Inhibitor Mechanisms (6 papers) and Receptor Mechanisms and Signaling (5 papers). The work is most often cited by research in Hematology (990 citations), Internal Medicine (229 citations), Immunology and Allergy (328 citations), Immunology (680 citations) and Genetics (297 citations). Dean A. Handley has collaborated with scholars based in United States, Japan and United Kingdom. Frequent co-authors include Peter P. Nawroth, D Stern, Robert N. Saunders, Charles T. Esmon, Ilan Bank, Leonard Chess, Shu Chien, Georgina M. Nemecek, Ronald G. Van Valen and Shaun R. Coughlin. Their work appears in journals such as Prostaglandins, Proceedings of the National Academy of Sciences, Thrombosis and Haemostasis, The Lancet and The Journal of Experimental Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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