David M. Sansom

14.8k total citations · 5 hit papers
104 papers, 9.6k citations indexed

About

David M. Sansom is a scholar working on Immunology, Oncology and Genetics. According to data from OpenAlex, David M. Sansom has authored 104 papers receiving a total of 9.6k indexed citations (citations by other indexed papers that have themselves been cited), including 87 papers in Immunology, 20 papers in Oncology and 12 papers in Genetics. Recurrent topics in David M. Sansom's work include T-cell and B-cell Immunology (69 papers), Immune Cell Function and Interaction (64 papers) and Immunotherapy and Immune Responses (19 papers). David M. Sansom is often cited by papers focused on T-cell and B-cell Immunology (69 papers), Immune Cell Function and Interaction (64 papers) and Immunotherapy and Immune Responses (19 papers). David M. Sansom collaborates with scholars based in United Kingdom, United States and Canada. David M. Sansom's co-authors include Lucy S. K. Walker, Yong Zheng, Neil Halliday, Behzad Rowshanravan, Claire N. Manzotti, Louisa Jeffery, Omar Qureshi, Fiona Burke, Tie Zheng Hou and Zoe Briggs and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

David M. Sansom

103 papers receiving 9.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

2011 1.3k citations Omar Qureshi, Yong Zheng et al. Science profile →
CTLA-4: a moving target in immunotherapy

2017 876 citations Behzad Rowshanravan, Neil Halliday et al. Blood profile →
1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3

2009 625 citations Louisa Jeffery, Fiona Burke et al. The Journal of Immunology profile →
Normal human pregnancy is associated with an elevation in the immune suppressive CD25⁺ CD4⁺ regulatory T‐cell subset

2004 612 citations Yong Zheng, David M. Sansom et al. Immunology profile →
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

2011 572 citations Lucy S. K. Walker, David M. Sansom profile →

Peers

Countries citing papers authored by David M. Sansom

Since Specialization

Citations

This map shows the geographic impact of David M. Sansom's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David M. Sansom with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David M. Sansom more than expected).

Fields of papers citing papers by David M. Sansom

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David M. Sansom. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David M. Sansom. The network helps show where David M. Sansom may publish in the future.

Co-authorship network of co-authors of David M. Sansom

This figure shows the co-authorship network connecting the top 25 collaborators of David M. Sansom. A scholar is included among the top collaborators of David M. Sansom based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David M. Sansom. David M. Sansom is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development 2024 ·Frontiers in Immunology ·(unknown), (unknown), Benoît Bilanges, (unknown), Jens Hukelmann, (unknown), James R. Edgar, David M. Sansom, Cheryl L. Scudamore, Rahul Roychoudhuri, Oliver A. Garden, Bart Vanhaesebroeck, Klaus Okkenhaug	2
2	The CTLA ‐4 immune checkpoint protein regulates PD‐L1 : PD ‐1 interaction via transendocytosis of its ligand CD80 2023 ·The EMBO Journal ·Alan Kennedy, (unknown), Claudia Hinze, Erin Waters, Cayman Williams, Neil Halliday, Simon J. Dovedi, David M. Sansom	14
3	Therapeutic gene editing of T cells to correct CTLA-4 insufficiency 2022 ·Science Translational Medicine ·Thomas A. Fox, (unknown), Lina Petersone, Erin Waters, Natalie M. Edner, (unknown), (unknown), Claudia Hinze, Cayman Williams, Adriana S. Albuquerque, Alan Kennedy, Anne M. Pesenacker, Pietro Genovese, Lucy S. K. Walker, Siobhan O. Burns, David M. Sansom, Claire Booth, Emma Morris	21
4	CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis 2021 ·Frontiers in Immunology ·Blagoje Soskic, Louisa Jeffery, Alan Kennedy, David H. Gardner, Tie Zheng Hou, Neil Halliday, Cayman Williams, Daniel Janman, Behzad Rowshanravan, Gideon M. Hirschfield, David M. Sansom	27
5	Measuring CTLA-4-Dependent Suppressive Function in Regulatory T Cells 2019 ·Methods in molecular biology ·Tie Zheng Hou, Omar Qureshi, David M. Sansom	8
6	Characterization of CTLA4 Trafficking and Implications for Its Function 2018 ·Biophysical Journal ·Sahamoddin Khailaie, Behzad Rowshanravan, Philippe A. Robert, Erin Waters, Neil Halliday, (unknown), Lucy S. K. Walker, David M. Sansom, Michael Meyer‐Hermann	37
7	Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations 2017 ·Blood ·Tie Zheng Hou, Nisha Verma, Jennifer Wanders, Alan Kennedy, Blagoje Soskic, Daniel Janman, Neil Halliday, Behzad Rowshanravan, Austen Worth, Waseem Qasim, Helen Baxendale, Hans J. Stauss, Suranjith L. Seneviratne, Olaf Neth, Peter Olbrich, Sophie Hambleton, Peter D. Arkwright, Siobhan O. Burns, Lucy S. K. Walker, David M. Sansom	71
8	Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint 2017 ·Journal of Autoimmunity ·Louisa Jeffery, (unknown), (unknown), Andrew Filer, David M. Sansom, Martin Hewison, Karim Raza	21
9	Confusing signals: Recent progress in CTLA-4 biology 2015 ·Trends in Immunology ·Lucy S. K. Walker, David M. Sansom	269
10	Loss of CD28 Expression by Liver-Infiltrating T Cells Contributes to Pathogenesis of Primary Sclerosing Cholangitis 2014 ·Gastroenterology ·Evaggelia Liaskou, Louisa Jeffery, Palak Trivedi, Gary Reynolds, Shankar Suresh, Tony Bruns, David Adams, David M. Sansom, Gideon M. Hirschfield	68
11	Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation 2012 ·Journal of Biological Chemistry ·Omar Qureshi, Satdip Kaur, Tie Zheng Hou, Louisa Jeffery, Natalie S. Poulter, Zoe Briggs, Rupert Kenefeck, Anna K. Willox, Stephen Royle, Joshua Z. Rappoport, David M. Sansom	122
12	Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4 breakdown → 2011 ·Science ·Omar Qureshi, Yong Zheng, Kyoko Nakamura, Kesley Attridge, Claire N. Manzotti, Emily M. Schmidt, Jennifer Baker, Louisa Jeffery, Satdip Kaur, Zoe Briggs, Tie Zheng Hou, Clare E. Futter, Graham Anderson, Lucy S. K. Walker, David M. Sansom	1323
13	CTLA-4 Controls Regulatory T Cell Peripheral Homeostasis and Is Required for Suppression of Pancreatic Islet Autoimmunity 2009 ·The Journal of Immunology ·Emily M. Schmidt, Chun Jing Wang, (unknown), Louise E. Clough, Omar Qureshi, Margaret Goodall, Abul K. Abbas, Arlene H. Sharpe, David M. Sansom, Lucy S. K. Walker	125
14	1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3 breakdown → 2009 ·The Journal of Immunology ·Louisa Jeffery, Fiona Burke, (unknown), Yong Zheng, Omar Qureshi, Martin Hewison, Lucy S. K. Walker, David A. Lammas, Karim Raza, David M. Sansom	625
15	Acquisition of Suppressive Function by Activated Human CD4+CD25− T Cells Is Associated with the Expression of CTLA-4 Not FoxP3 2008 ·The Journal of Immunology ·Yong Zheng, Claire N. Manzotti, Fiona Burke, (unknown), Omar Qureshi, Lucy S. K. Walker, David M. Sansom	74
16	Exocytosis of CTLA-4 Is Dependent on Phospholipase D and ADP Ribosylation Factor-1 and Stimulated during Activation of Regulatory T Cells 2005 ·The Journal of Immunology ·(unknown), Yong Zheng, Claire N. Manzotti, (unknown), Michael K. P. Liu, Fiona Burke, Dale Powner, Michael J.O. Wakelam, David M. Sansom	74
17	CD86 and CD80 Differentially Modulate the Suppressive Function of Human Regulatory T Cells 2004 ·The Journal of Immunology ·Yong Zheng, Claire N. Manzotti, Michael Liu, Fiona Burke, (unknown), David M. Sansom	221
18	Lack of costimulation by both sphingomyelinase and C2 ceramide in resting human T cells 2000 ·Immunology ·(unknown), David M. Sansom	12
19	Human vascular endothelial cells process and present autoantigen to human T cell lines 1995 ·International Immunology ·Caroline O.S. Savage, (unknown), Gillian Harcourt, J Picard, W.A. King, David M. Sansom, Nicholas Willcox	56
20	Human γδ Cells Are Resistant to Induction of Anergy but Not to Induction of Cell Death in Vitro 1995 ·Cellular Immunology ·Graham Pawelec, (unknown), Martina Boshell, (unknown), Arnika Rehbein, (unknown), Heike Pohla, Kurt Schaudt, David M. Sansom	4

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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