David M. MacAlpine

9.9k total citations · 2 hit papers
62 papers, 5.0k citations indexed

About

David M. MacAlpine is a scholar working on Molecular Biology, Genetics and Plant Science. According to data from OpenAlex, David M. MacAlpine has authored 62 papers receiving a total of 5.0k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Molecular Biology, 9 papers in Genetics and 7 papers in Plant Science. Recurrent topics in David M. MacAlpine's work include Genomics and Chromatin Dynamics (44 papers), DNA Repair Mechanisms (36 papers) and Epigenetics and DNA Methylation (19 papers). David M. MacAlpine is often cited by papers focused on Genomics and Chromatin Dynamics (44 papers), DNA Repair Mechanisms (36 papers) and Epigenetics and DNA Methylation (19 papers). David M. MacAlpine collaborates with scholars based in United States, United Kingdom and Switzerland. David M. MacAlpine's co-authors include Stephen P. Bell, Heather K. MacAlpine, Jason A. Belsky, Matthew L. Eaton, Steven Henikoff, Sara Powell, Geneviève Almouzni, Sukhyun Kang, C Wirbelauer and Fred van Leeuwen and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

David M. MacAlpine

61 papers receiving 5.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

2004 634 citations David M. MacAlpine, Stephen P. Bell et al. profile →
Unlocking the secrets of the genome

2009 609 citations S Celniker, Laura A. L. Dillon et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David M. MacAlpine United States	34	4.6k	932	776	362	269	62	5.0k
Joel C. Eissenberg United States	43	5.6k 1.2×	1.9k 2.0×	877 1.1×	402 1.1×	169 0.6×	87	6.2k
Lori L. Wallrath United States	36	3.6k 0.8×	1.0k 1.1×	515 0.7×	316 0.9×	116 0.4×	70	4.0k
Peter Romanienko United States	17	3.4k 0.7×	708 0.8×	917 1.2×	330 0.9×	546 2.0×	29	3.9k
Gloria A. Brar United States	23	6.1k 1.3×	634 0.7×	770 1.0×	516 1.4×	587 2.2×	40	6.6k
Karl Ekwall Sweden	43	5.6k 1.2×	2.1k 2.3×	410 0.5×	547 1.5×	234 0.9×	123	6.1k
André Verdel France	24	4.1k 0.9×	1.3k 1.4×	302 0.4×	124 0.3×	425 1.6×	38	4.5k
Chris Seidel United States	28	2.8k 0.6×	699 0.8×	344 0.4×	407 1.1×	202 0.8×	49	3.2k
Yuki Katou Japan	42	5.7k 1.2×	1.1k 1.2×	668 0.9×	1.4k 3.9×	409 1.5×	62	6.1k
Nancy M. Hollingsworth United States	32	4.0k 0.9×	631 0.7×	309 0.4×	1.2k 3.4×	353 1.3×	50	4.2k
Hervé Le Hir France	39	6.4k 1.4×	383 0.4×	380 0.5×	191 0.5×	395 1.5×	68	6.9k

Countries citing papers authored by David M. MacAlpine

Since Specialization

Citations

This map shows the geographic impact of David M. MacAlpine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David M. MacAlpine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David M. MacAlpine more than expected).

Fields of papers citing papers by David M. MacAlpine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David M. MacAlpine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David M. MacAlpine. The network helps show where David M. MacAlpine may publish in the future.

Co-authorship network of co-authors of David M. MacAlpine

This figure shows the co-authorship network connecting the top 25 collaborators of David M. MacAlpine. A scholar is included among the top collaborators of David M. MacAlpine based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David M. MacAlpine. David M. MacAlpine is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Zhu, Wei, Yuning Zhang, Ariel Afek, et al.. (2025). DNA mutagenesis driven by transcription factor competition with mismatch repair. Cell. 188(20). 5735–5747.e15.

MacAlpine, Heather K., et al.. (2023). Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase. Genome Research. 33(12). 2108–2118. 2 indexed citations

MacAlpine, David M., et al.. (2021). RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data. Nucleic Acids Research. 49(14). 7925–7938. 3 indexed citations

Memişoğlu, Gönen, Heather K. MacAlpine, Wei Zhu, et al.. (2021). Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication. Genome Research. 31(5). 775–788. 10 indexed citations

MacAlpine, Heather K., et al.. (2021). Linking the dynamics of chromatin occupancy and transcription with predictive models. Genome Research. 31(6). 1035–1046. 6 indexed citations

Azmi, Ishara F., Shinya Watanabe, Michael F. Maloney, et al.. (2017). Nucleosomes influence multiple steps during replication initiation. eLife. 6. 48 indexed citations

Li, Yulong, et al.. (2016). Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila. Nucleic Acids Research. 44(15). gkw333–gkw333. 24 indexed citations

Prinz, Joseph A., et al.. (2015). Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. Molecular and Cellular Biology. 35(12). 2131–2143. 13 indexed citations

Powell, Sara, Heather K. MacAlpine, Joseph A. Prinz, et al.. (2015). Dynamic loading and redistribution of the Mcm2‐7 helicase complex through the cell cycle. The EMBO Journal. 34(4). 531–543. 66 indexed citations

10.

Lubelsky, Yoav, et al.. (2014). DNA replication and transcription programs respond to the same chromatin cues. Genome Research. 24(7). 1102–1114. 56 indexed citations

11.

Lubelsky, Yoav, Heather K. MacAlpine, & David M. MacAlpine. (2012). Genome-wide localization of replication factors. Methods. 57(2). 187–195. 16 indexed citations

12.

Ding, Queying & David M. MacAlpine. (2011). Defining the replication program through the chromatin landscape. Critical Reviews in Biochemistry and Molecular Biology. 46(2). 165–179. 27 indexed citations

13.

Eaton, Matthew L., et al.. (2010). Chromatin signatures of the Drosophila replication program. Genome Research. 21(2). 164–174. 141 indexed citations

14.

Celniker, S, Laura A. L. Dillon, Mark Gerstein, et al.. (2009). Unlocking the Secrets of the Genome. Carolina Digital Repository (University of North Carolina at Chapel Hill). 1 indexed citations

15.

MacAlpine, Heather K., Raluca Gordân, Sara Powell, Alexander J. Hartemink, & David M. MacAlpine. (2009). Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading. Genome Research. 20(2). 201–211. 218 indexed citations

16.

Tanny, Robyn E., David M. MacAlpine, Hannah G. Blitzblau, & Stephen P. Bell. (2006). Genome-wide Analysis of Re-replication Reveals Inhibitory Controls That Target Multiple Stages of Replication Initiation. Molecular Biology of the Cell. 17(5). 2415–2423. 31 indexed citations

17.

Claycomb, Julie M., David M. MacAlpine, James G. Evans, Stephen P. Bell, & Terry L. Orr‐Weaver. (2002). Visualization of replication initiation and elongation in Drosophila. The Journal of Cell Biology. 159(2). 225–236. 69 indexed citations

18.

MacAlpine, David M., Philip S. Perlman, & Ronald A. Butow. (2000). The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. The EMBO Journal. 19(4). 767–775. 74 indexed citations

19.

Zhang, Zhi, et al.. (1997). Developmental Regulation of DNA Replication: Replication Fork Barriers and Programmed Gene Amplification in Tetrahymena thermophila. Molecular and Cellular Biology. 17(10). 6147–6156. 39 indexed citations

20.

MacAlpine, David M., Zhi Zhang, & Geoffrey M. Kapler. (1997). Type I Elements Mediate Replication Fork Pausing at Conserved Upstream Sites in the Tetrahymena thermophila Ribosomal DNA Minichromosome. Molecular and Cellular Biology. 17(8). 4517–4525. 29 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact