David L. DeWitt

20.8k total citations · 6 hit papers
109 papers, 17.4k citations indexed

About

David L. DeWitt is a scholar working on Pharmacology, Molecular Biology and Genetics. According to data from OpenAlex, David L. DeWitt has authored 109 papers receiving a total of 17.4k indexed citations (citations by other indexed papers that have themselves been cited), including 70 papers in Pharmacology, 49 papers in Molecular Biology and 39 papers in Genetics. Recurrent topics in David L. DeWitt's work include Inflammatory mediators and NSAID effects (68 papers), Estrogen and related hormone effects (39 papers) and Eicosanoids and Hypertension Pharmacology (17 papers). David L. DeWitt is often cited by papers focused on Inflammatory mediators and NSAID effects (68 papers), Estrogen and related hormone effects (39 papers) and Eicosanoids and Hypertension Pharmacology (17 papers). David L. DeWitt collaborates with scholars based in United States, Germany and France. David L. DeWitt's co-authors include William L. Smith, R. Michael Garavito, Elizabeth A. Meade, Muraleedharan G. Nair, Gale M. Strasburg, Christopher D. Breder, Odette Laneuville, Richard P. Kraig, James Otto and J. Ian Gray and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

David L. DeWitt

108 papers receiving 16.8k citations

Hit Papers

Cyclooxygenases: Structural, Cellular, and Molecular Biology 1991 2026 2002 2014 2000 1996 1993 1996 1991 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Cyclooxygenases: Structural, Cellular, and Molecular Biology
    2000 2.4k citations William L. Smith, David L. DeWitt et al. profile →
  2. Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2
    1996 1.7k citations William L. Smith, R. Michael Garavito et al. Journal of Biological Chemistry profile →
  3. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.
    1993 1.1k citations Elizabeth A. Meade, William L. Smith et al. Journal of Biological Chemistry profile →
  4. Prostaglandin Endoperoxide H Synthases-1 and -2
    1996 625 citations William L. Smith, David L. DeWitt profile →
  5. Prostaglandin endoperoxide synthase: regulation of enzyme expression
    1991 566 citations David L. DeWitt Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism profile →
  6. Antioxidant and Antiinflammatory Activities of Anthocyanins and Their Aglycon, Cyanidin, from Tart Cherries
    1999 541 citations Muraleedharan G. Nair, David L. DeWitt et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
David L. DeWitt United States 59 9.1k 4.8k 3.6k 2.9k 1.7k 109 17.4k
Jaime L. Masferrer United States 56 9.7k 1.1× 4.1k 0.8× 4.3k 1.2× 2.9k 1.0× 1.2k 0.7× 135 17.9k
Karen Seibert United States 53 11.2k 1.2× 3.9k 0.8× 4.5k 1.3× 2.9k 1.0× 1.1k 0.7× 99 18.8k
Peter C. Isakson United States 63 9.2k 1.0× 3.5k 0.7× 2.6k 0.7× 2.2k 0.8× 2.2k 1.3× 134 16.8k
Colin Funk United States 65 4.7k 0.5× 6.8k 1.4× 2.0k 0.6× 3.5k 1.2× 3.7k 2.2× 183 17.6k
Mats Hámberg Sweden 80 8.8k 1.0× 9.2k 1.9× 1.7k 0.5× 6.8k 2.4× 1.5k 0.9× 336 27.1k
Thomas E. Eling United States 67 3.5k 0.4× 5.7k 1.2× 1.4k 0.4× 1.9k 0.7× 2.3k 1.4× 294 15.0k
Philip Needleman United States 72 6.1k 0.7× 6.0k 1.2× 1.7k 0.5× 4.4k 1.5× 1.2k 0.7× 263 20.8k
Jane A. Mitchell United Kingdom 66 5.4k 0.6× 4.6k 0.9× 1.3k 0.4× 3.0k 1.1× 2.6k 1.5× 268 19.1k
Oliver Werz Germany 63 5.1k 0.6× 5.7k 1.2× 1.5k 0.4× 1.5k 0.5× 1.8k 1.0× 450 15.0k
Tadashi Tanabe Japan 56 3.5k 0.4× 4.0k 0.8× 1.8k 0.5× 1.2k 0.4× 1.0k 0.6× 146 9.6k

Countries citing papers authored by David L. DeWitt

Since Specialization
Citations

This map shows the geographic impact of David L. DeWitt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David L. DeWitt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David L. DeWitt more than expected).

Fields of papers citing papers by David L. DeWitt

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David L. DeWitt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David L. DeWitt. The network helps show where David L. DeWitt may publish in the future.

Co-authorship network of co-authors of David L. DeWitt

This figure shows the co-authorship network connecting the top 25 collaborators of David L. DeWitt. A scholar is included among the top collaborators of David L. DeWitt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David L. DeWitt. David L. DeWitt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Mulabagal, Vanisree, et al.. (2009). Anthocyanin Content, Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Activities of Sweet and Sour Cherries. Journal of Agricultural and Food Chemistry. 57(4). 1239–1246. 111 indexed citations
2.
DeWitt, David L., et al.. (2009). Liposomal Reconstitution of Monotopic Integral Membrane Proteins. Methods in molecular biology. 606. 83–94. 3 indexed citations
3.
Mulabagal, Vanisree, et al.. (2008). Non-nutritive functional agents in rattan-shoots, a food consumed by native people in the Philippines. Food Chemistry. 110(4). 991–996. 7 indexed citations
4.
Mulabagal, Vanisree, Steve van Nocker, David L. DeWitt, & Muraleedharan G. Nair. (2007). Cultivars of Apple Fruits That Are Not Marketed with Potential for Anthocyanin Production. Journal of Agricultural and Food Chemistry. 55(20). 8165–8169. 23 indexed citations
5.
Leipprandt, Jeffrey R., et al.. (2006). Topography of the Prostaglandin Endoperoxide H2 Synthase-2 in Membranes. Journal of Biological Chemistry. 281(38). 28354–28364. 16 indexed citations
6.
Nair, Muraleedharan G., et al.. (2002). Bioactivity of alkamides isolated from Echinacea purpurea (L.) Moench.. Phytomedicine. 9(3). 249–253. 61 indexed citations
7.
Henry, Geneive E., et al.. (2002). Antioxidant and Cyclooxygenase Activities of Fatty Acids Found in Food. Journal of Agricultural and Food Chemistry. 50(8). 2231–2234. 196 indexed citations
8.
Li, Yi, Tim Smith, Sharon Grabski, & David L. DeWitt. (1998). The Membrane Association Sequences of the Prostaglandin Endoperoxide Synthases-1 and -2 Isozymes. Journal of Biological Chemistry. 273(45). 29830–29837. 36 indexed citations
9.
Sarsfield, S J, Heather F. Bigg, Tim E. Cawston, et al.. (1997). Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. The Journal of Immunology. 158(7). 3165–3173. 254 indexed citations
10.
Corcoran, Marta L., Yahong Zhang, H.L.S. Wong, et al.. (1996). Suppression of Prostaglandin H Synthase-2 Induction in Human Monocytes byin Vitroorin VivoAdministration of Interleukin 4. Cellular Immunology. 173(2). 252–260. 10 indexed citations
11.
Smith, William L., R. Michael Garavito, & David L. DeWitt. (1996). Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2. Journal of Biological Chemistry. 271(52). 33157–33160. 1711 indexed citations breakdown →
12.
Otto, James, et al.. (1995). Localization of Prostaglandin Endoperoxide Synthase-1 to the Endoplasmic-Reticulum and Nuclear-Envelope Is Independent of Its C-Terminal Tetrapeptide-Ptel. Archives of Biochemistry and Biophysics. 317(2). 457–463. 22 indexed citations
13.
Hulkower, Keren I., Stanley J. Wertheimer, Wayne Levin, et al.. (1994). Interleukin‐1β induces cytosolic phospholipase a2 and prostaglandin h synthase in rheumatoid synovial fibroblasts. Arthritis & Rheumatism. 37(5). 653–661. 105 indexed citations
14.
Martin, Michael U., Detlef Neumann, Torsten Hoff, et al.. (1994). Interleukin-1-induced cyclooxygenase 2 expression is suppressed by cyclosporin A in rat mesangial cells. Kidney International. 45(1). 150–158. 149 indexed citations
15.
Meade, Elizabeth A., William L. Smith, & David L. DeWitt. (1993). Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.. Journal of Biological Chemistry. 268(9). 6610–6614. 1084 indexed citations breakdown →
16.
Meade, Elizabeth A., et al.. (1992). Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences. Archives of Biochemistry and Biophysics. 293(2). 391–400. 168 indexed citations
17.
Shimokawa, T., Richard J. Kulmacz, David L. DeWitt, & William L. Smith. (1990). Tyrosine 385 of prostaglandin endoperoxide synthase is required for cyclooxygenase catalysis. Journal of Biological Chemistry. 265(33). 20073–20076. 199 indexed citations
18.
Koehler, L., Ralf Hass, Klaus Wessel, et al.. (1990). Altered arachidonic acid metabolism during differentiation of the human monoblastoid cell line U937. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1042(3). 395–403. 43 indexed citations
19.
DeWitt, David L. & William L. Smith. (1983). Purification of prostacyclin synthase from bovine aorta by immunoaffinity chromatography. Evidence that the enzyme is a hemoprotein.. Journal of Biological Chemistry. 258(5). 3285–3293. 83 indexed citations
20.
DeWitt, David L. & William L. Smith. (1982). [35] Monoclonal antibodies against PGI2 synthase: An immunoradiometric assay for quantitating the enzyme. Methods in enzymology on CD-ROM/Methods in enzymology. 86. 240–246. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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