David Farrens

6.8k total citations · 2 hit papers
68 papers, 5.7k citations indexed

About

David Farrens is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Plant Science. According to data from OpenAlex, David Farrens has authored 68 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 60 papers in Molecular Biology, 45 papers in Cellular and Molecular Neuroscience and 9 papers in Plant Science. Recurrent topics in David Farrens's work include Receptor Mechanisms and Signaling (45 papers), Photoreceptor and optogenetics research (34 papers) and Neuroscience and Neuropharmacology Research (18 papers). David Farrens is often cited by papers focused on Receptor Mechanisms and Signaling (45 papers), Photoreceptor and optogenetics research (34 papers) and Neuroscience and Neuropharmacology Research (18 papers). David Farrens collaborates with scholars based in United States, Denmark and Japan. David Farrens's co-authors include H. Gobind Khorana, Wayne L. Hubbell, Ke Yang, Christian Altenbach, Brian K. Kobilka, Jay M. Janz, Steven Mansoor, Jonathan F. Fay, Jacqueline J. Steenhuis and Pejman Ghanouni and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

David Farrens

67 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin

1996 994 citations David Farrens, Christian Altenbach et al. profile →
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

2019 318 citations David Farrens, Brian K. Kobilka et al. profile →

Peers

Countries citing papers authored by David Farrens

Since Specialization

Citations

This map shows the geographic impact of David Farrens's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Farrens with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Farrens more than expected).

Fields of papers citing papers by David Farrens

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Farrens. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Farrens. The network helps show where David Farrens may publish in the future.

Co-authorship network of co-authors of David Farrens

This figure shows the co-authorship network connecting the top 25 collaborators of David Farrens. A scholar is included among the top collaborators of David Farrens based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Farrens. David Farrens is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	A novel "bio-tag" for cryo-EM studies based on the small, electron-dense protein Csp1 2025 ·Biophysical Journal ·(unknown), (unknown), David Farrens	0
2	Styrene-maleic acid copolymer effects on the function of the GPCR rhodopsin in lipid nanoparticles 2021 ·Biophysical Journal ·István Szundi, (unknown), Eefei Chen, David Farrens, David S. Kliger	10
3	Functional integrity of membrane protein rhodopsin solubilized by styrene-maleic acid copolymer 2021 ·Biophysical Journal ·(unknown), (unknown), István Szundi, Jonathan F. Fay, Eefei Chen, (unknown), David S. Kliger, David Farrens	7
4	Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons 2021 ·eLife ·Seksiri Arttamangkul, Emily J. Platt, (unknown), David Farrens	14
5	Novel fluorescent GPCR biosensor detects retinal equilibrium binding to opsin and active G protein and arrestin signaling conformations 2020 ·Journal of Biological Chemistry ·(unknown), (unknown), David Farrens	1
6	Purification of Functional CB1 and Analysis by Site-Directed Fluorescence Labeling Methods 2017 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Jonathan F. Fay, David Farrens	7
7	Retinal Attachment Instability Is Diversified among Mammalian Melanopsins 2015 ·Journal of Biological Chemistry ·Hisao Tsukamoto, Yoshihiro Kubo, David Farrens, Mitsumasa Koyanagi, Akihisa Terakita, Yuji Furutani	21
8	Conformational Selection and Equilibrium Governs the Ability of Retinals to Bind Opsin 2014 ·Journal of Biological Chemistry ·(unknown), David Farrens	20
9	A Constitutively Activating Mutation Alters the Dynamics and Energetics of a Key Conformational Change in a Ligand-free G Protein-coupled Receptor 2013 ·Journal of Biological Chemistry ·Hisao Tsukamoto, David Farrens	33
10	What site-directed labeling studies tell us about the mechanism of rhodopsin activation and G-protein binding 2010 ·Photochemical & Photobiological Sciences ·David Farrens	21
11	The Magnitude of the Light-induced Conformational Change in Different Rhodopsins Correlates with Their Ability to Activate G Proteins 2009 ·Journal of Biological Chemistry ·Hisao Tsukamoto, David Farrens, Mitsumasa Koyanagi, Akihisa Terakita	44
12	Dynamics of Arrestin-Rhodopsin Interactions 2007 ·Journal of Biological Chemistry ·M. Sommer, David Farrens, J. Hugh McDowell, (unknown), W. Clay Smith	47
13	Arrestin can act as a regulator of rhodopsin photochemistry 2006 ·Vision Research ·M. Sommer, David Farrens	35
14	The Conformations of the Manganese Transport Regulator of Bacillus subtilis in its Metal-free State 2006 ·Journal of Molecular Biology ·Mark A. DeWitt, Joseph I. Kliegman, John D. Helmann, Richard G. Brennan, David Farrens, Arthur Glasfeld	28
15	Role of the Retinal Hydrogen Bond Network in Rhodopsin Schiff Base Stability and Hydrolysis 2004 ·Journal of Biological Chemistry ·Jay M. Janz, David Farrens	64
16	Assessing structural elements that influence Schiff base stability: mutants E113Q and D190N destabilize rhodopsin through different mechanisms 2003 ·Vision Research ·Jay M. Janz, David Farrens	30
17	Functionally Different Agonists Induce Distinct Conformations in the G Protein Coupling Domain of the β2Adrenergic Receptor 2001 ·Journal of Biological Chemistry ·Pejman Ghanouni, Zygmunt Gryczyński, Jacqueline J. Steenhuis, Tae Weon Lee, David Farrens, Joseph R. Lakowicz, Brian K. Kobilka	312
18	Structural Features and Light-Dependent Changes in the Cytoplasmic Interhelical E−F Loop Region of Rhodopsin: A Site-Directed Spin-Labeling Study 1996 ·Biochemistry ·Christian Altenbach, Ke Yang, David Farrens, Zohreh Farahbakhsh, H. G. Khorana, Wayne L. Hubbell	226
19	THE DISTANCE BETWEEN THE PHYTOCHROME CHROMOPHORE AND THE N‐TERMINAL CHAIN DECREASES DURING PHOTOTRANSFORMATION. A NOVEL FLUORESCENCE ENERGY TRANSFER METHOD USING LABELED ANTIBODY FRAGMENTS 1992 ·Photochemistry and Photobiology ·David Farrens, (unknown), Lee H. Pratt, Pill‐Soon Song	15
20	Surface enhanced resonance Raman scattering (SERRS) as a probe of the structural differences between the Pr and Pfr forms of phytochrome 1989 ·FEBS Letters ·Bernard N. Rospendowski, David Farrens, Therese M. Cotton, Pill-Soon Song	25

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact