David E. Sleat

6.6k citations

79 papers · 5.2k indexed · 1 hit paper · h-index 40

Physiology top 0.2%
- Lysosomal Storage Disorders Research 50
- Calcium signaling and nucleotide metabolism 9
Physiology top 0.5%
- Lysosomal Storage Disorders Research 50
- Calcium signaling and nucleotide metabolism 9
Cell Biology top 0.5%
- Cellular transport and secretion 41
Endocrinology top 2%
Molecular Biology top 5%
- Glycosylation and Glycoproteins Research 17
Plant Science
- Plant Virus Research Studies 17
Organic Chemistry
- Carbohydrate Chemistry and Synthesis 7
Ecology
- Bacteriophages and microbial interactions 6
Biotechnology
- Transgenic Plants and Applications 5

Co-authors: Peter Lobel István Sohár Henry Lackland T. M. A. Wilson Philip Turner Michel Jadot Daniel Gallie John W. Watts
Cited by: Physiology Cell Biology
Journals: Molecular & Cellular Proteomics (8 papers)Molecular Therapy (7 papers)Biochemical Journal (7 papers)
Partner nations: United States United Kingdom Belgium

In The Last Decade

David E. Sleat

79 papers receiving 5.1k citations

Hit Papers

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Peers

Countries citing papers authored by David E. Sleat

Since Specialization

Citations

This map shows the geographic impact of David E. Sleat's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David E. Sleat with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David E. Sleat more than expected).

Fields of papers citing papers by David E. Sleat

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David E. Sleat. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David E. Sleat. The network helps show where David E. Sleat may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David E. Sleat, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David E. Sleat Line = papers co-authored together David E. Sleat links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Elevated levels of tripeptidyl peptidase 1 do not ameliorate pathogenesis in a mouse model of Alzheimer disease Neurobiology of Aging ·David E. Sleat,晋城野,Whitney Banach‐Petrosky,Katherine E. Larrimore,李高芬,Dana Cruz,S. Dori-Hacohen,Frederick R. Maxfield,Benjamin A. Samuels,Peter Lobel	2022	2
2	Analysis of Brain and Cerebrospinal Fluid from Mouse Models of the Three Major Forms of Neuronal Ceroid Lipofuscinosis Reveals Changes in the Lysosomal Proteome Molecular & Cellular Proteomics ·David E. Sleat,Jennifer A. Wiseman,Mukarram El-Banna,Haiyan Zheng,Caifeng Zhao,寿史佐原,Dirk F. Moore,Peter Lobel	2019	30
3	Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis PLoS ONE ·高媛,Jennifer A. Wiseman,Mukarram El-Banna,Peter Lobel,David E. Sleat	2018	3
4	Chronic Enzyme Replacement to the Brain of a Late Infantile Neuronal Ceroid Lipofuscinosis Mouse Has Differential Effects on Phenotypes of Disease Molecular Therapy — Methods & Clinical Development ·Jennifer A. Wiseman,Yu Meng,高媛,Paul G. Matteson,James H. Millonig,Dirk F. Moore,David E. Sleat,Peter Lobel	2017	13
5	Potential Pitfalls and Solutions for Use of Fluorescent Fusion Proteins to Study the Lysosome PLoS ONE ·Ling Huang,Douglas H. Pike,David E. Sleat,Vikas Nanda,Peter Lobel	2014	47
6	Extending the Mannose 6-Phosphate Glycoproteome by High Resolution/Accuracy Mass Spectrometry Analysis of Control and Acid Phosphatase 5-Deficient Mice Molecular & Cellular Proteomics ·David E. Sleat,Pengling Sun,Jennifer A. Wiseman,Ling Huang,Mukarram El-Banna,Haiyan Zheng,Dirk F. Moore,Peter Lobel	2013	41
7	Proteomics of the lysosome Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Torben Lübke,Peter Lobel,David E. Sleat	2008	215
8	Proteomics Analysis of Serum from Mutant Mice Reveals Lysosomal Proteins Selectively Transported by Each of the Two Mannose 6-Phosphate Receptors Molecular & Cellular Proteomics ·Meiqian Qian,David E. Sleat,Haiyan Zheng,Dirk F. Moore,Peter Lobel	2007	71
9	The human urine mannose 6-phosphate glycoproteome Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·David E. Sleat,Haiyan Zheng,Peter Lobel	2006	29
10	Identification and Validation of Mannose 6-Phosphate Glycoproteins in Human Plasma Reveal a Wide Range of Lysosomal and Non-lysosomal Proteins Molecular & Cellular Proteomics ·David E. Sleat,Yanhong Wang,István Sohár,Henry Lackland,Yan Li,Hong Li,Haiyan Zheng,Peter Lobel	2006	64
11	Demonstration of Lysosomal Localization for the Mammalian Ependymin-related Protein Using Classical Approaches Combined with a Novel Density Shift Method Journal of Biological Chemistry ·Maria Cecilia Della Valle,David E. Sleat,István Sohár,Ting Wen,John E. Pintar,Michel Jadot,Peter Lobel	2006	19
12	The human brain mannose 6‐phosphate glycoproteome: A complex mixture composed of multiple isoforms of many soluble lysosomal proteins PROTEOMICS ·David E. Sleat,Henry Lackland,Yanhong Wang,István Sohár,Gang Xiao,Hong Li,Peter Lobel	2005	84
13	Niemann-Pick Disease Type C: Spectrum of HE1 Mutations and Genotype/Phenotype Correlations in the NPC2 Group The American Journal of Human Genetics ·Gilles Millat,Karim Chikh,Saule Naureckiene,David E. Sleat,Anthony H. Fensom,Katsumi Higaki,M. Elleder,Peter Lobel,Marie T. Vanier	2001	119
14	Biochemical Characterization of a Lysosomal Protease Deficient in Classical Late Infantile Neuronal Ceroid Lipofuscinosis (LINCL) and Development of an Enzyme‐Based Assay for Diagnosis and Exclusion of LINCL in HUman Specimens and Animal Models Journal of Neurochemistry ·István Sohár,David E. Sleat,Michel Jadot,Peter Lobel	1999	72
15	Rat Brain Contains High Levels of Mannose-6-phosphorylated Glycoproteins Including Lysosomal Enzymes and Palmitoyl-Protein Thioesterase, an Enzyme Implicated in Infantile Neuronal Lipofuscinosis Journal of Biological Chemistry ·David E. Sleat,István Sohár,Henry Lackland,John Majercak,Peter Lobel	1996	100
16	Restricted replication of vesicular stomatitis virus in T lymphocytes is coincident with a deficiency in a cellular protein kinase required for viral transcription Journal of General Virology ·David E. Sleat,Nathaniel F. Chikkala,Suman Gautam,A K Banerjee	1992	7
17	Direct recovery ofin vitrotranscripts in a protected form suitable for prolonged storage and shipment at ambient temperatures Nucleic Acids Research ·Isabelle Jupin,David E. Sleat,Paul A. Watkins,T. M. A. Wilson	1989	8
18	Selective recovery of foreign gene transcripts as virus-like particles in TMV-infected transgenic tobaccos Nucleic Acids Research ·David E. Sleat,Daniel Gallie,John W. Watts,C. M. Deom,Philip Turner,Roger N. Beachy,T. M. A. Wilson	1988	25
19	Studies on the mechanism of translational enhancement by the 5′‐leader sequence of tobacco mosaic virus RNA European Journal of Biochemistry ·David E. Sleat,Roger Hull,Philip Turner,T. M. A. Wilson	1988	49
20	Characterisation of the 5′-leader sequence of tobacco mosaic virus RNA as a general enhancer of translation in vitro Gene ·David E. Sleat,Qinli Li,Richard Jefferson,Michael Bevan,Philip Turner,T. M. A. Wilson	1987	92

About David E. Sleat

David E. Sleat is a scholar working on Cell Biology, Physiology and Physiology, having authored 79 papers that have together received 5.2k indexed citations. Recurring topics across this work include Lysosomal Storage Disorders Research (50 papers), Cellular transport and secretion (41 papers), Glycosylation and Glycoproteins Research (17 papers), Plant Virus Research Studies (17 papers), Calcium signaling and nucleotide metabolism (9 papers), Carbohydrate Chemistry and Synthesis (7 papers), Bacteriophages and microbial interactions (6 papers) and Transgenic Plants and Applications (5 papers). The work is most often cited by research in Physiology (636 citations), Physiology (2.7k citations) and Cell Biology (1.6k citations). David E. Sleat has collaborated with scholars based in United States, United Kingdom and Belgium. Frequent co-authors include Peter Lobel, István Sohár, Henry Lackland, T. M. A. Wilson, Philip Turner, Michel Jadot, Daniel Gallie, John W. Watts, Marie T. Vanier and Peter Palukaitis. Their work appears in journals such as Molecular & Cellular Proteomics, Molecular Therapy, Biochemical Journal, Nucleic Acids Research and Journal of Proteome Research.

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