David C. Spink

4.6k total citations · 2 hit papers
74 papers, 3.9k citations indexed

About

David C. Spink is a scholar working on Health, Toxicology and Mutagenesis, Genetics and Pharmacology. According to data from OpenAlex, David C. Spink has authored 74 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Health, Toxicology and Mutagenesis, 21 papers in Genetics and 18 papers in Pharmacology. Recurrent topics in David C. Spink's work include Estrogen and related hormone effects (21 papers), Toxic Organic Pollutants Impact (20 papers) and Pharmacogenetics and Drug Metabolism (17 papers). David C. Spink is often cited by papers focused on Estrogen and related hormone effects (21 papers), Toxic Organic Pollutants Impact (20 papers) and Pharmacogenetics and Drug Metabolism (17 papers). David C. Spink collaborates with scholars based in United States, Canada and China. David C. Spink's co-authors include Barbara C. Spink, John F. Gierthy, Carrie L. Hayes, Thomas R. Sutter, David O. Carpenter, Joan Cao, Kathleen F. Arcaro, Nigel J. Walker, Li Xu and Laurence S. Kaminsky and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Science of The Total Environment.

In The Last Decade

David C. Spink

74 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.

1996 543 citations Carrie L. Hayes, David C. Spink et al. profile →
Legacy and Emerging Per- and Polyfluoroalkyl Substances: Analytical Techniques, Environmental Fate, and Health Effects

2021 219 citations David C. Spink et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David C. Spink United States	31	1.3k	1.1k	1.0k	831	619	74	3.9k
Shigeru Ohta Japan	42	1.6k 1.2×	1.8k 1.7×	452 0.4×	932 1.1×	433 0.7×	273	7.0k
John R. Foster United Kingdom	39	1.2k 0.9×	1.5k 1.4×	261 0.3×	811 1.0×	873 1.4×	125	4.4k
Ingvar Brandt Sweden	38	2.6k 1.9×	548 0.5×	465 0.5×	394 0.5×	743 1.2×	181	4.8k
Timothy R. Zacharewski United States	43	3.6k 2.7×	1.3k 1.2×	856 0.8×	311 0.4×	1.2k 2.0×	114	5.8k
Thomas A. Gasiewicz United States	53	3.3k 2.5×	1.7k 1.5×	600 0.6×	528 0.6×	2.0k 3.2×	130	6.7k
Stelvio M. Bandiera Canada	38	1.9k 1.4×	866 0.8×	237 0.2×	1.4k 1.7×	820 1.3×	108	4.3k
J. Thomas Sanderson Canada	39	2.3k 1.7×	785 0.7×	682 0.7×	234 0.3×	501 0.8×	109	4.9k
Margaret O. James United States	38	1.7k 1.3×	1.6k 1.5×	200 0.2×	868 1.0×	536 0.9×	173	4.6k
Kazumi Sugihara Japan	31	1.2k 0.9×	953 0.9×	203 0.2×	750 0.9×	261 0.4×	105	3.2k
Junsei Mimura Japan	43	2.6k 1.9×	3.5k 3.3×	798 0.8×	552 0.7×	1.8k 2.9×	76	8.0k

Countries citing papers authored by David C. Spink

Since Specialization

Citations

This map shows the geographic impact of David C. Spink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David C. Spink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David C. Spink more than expected).

Fields of papers citing papers by David C. Spink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David C. Spink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David C. Spink. The network helps show where David C. Spink may publish in the future.

Co-authorship network of co-authors of David C. Spink

This figure shows the co-authorship network connecting the top 25 collaborators of David C. Spink. A scholar is included among the top collaborators of David C. Spink based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David C. Spink. David C. Spink is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tran, Buu N., Richard Okoniewski, Barbara C. Spink, et al.. (2023). Androgenic steroids in Over-the-Counter dietary Supplements: Analysis for association with adverse health effects. Steroids. 193. 109199–109199. 6 indexed citations

Li, Lingyun, et al.. (2019). Potency Analysis of Medical Marijuana Products from New York State. Cannabis and Cannabinoid Research. 4(3). 195–203. 9 indexed citations

Cao, Zhimin, Stephanie Wemm, Liqiao Han, David C. Spink, & Edelgard Wulfert. (2019). Noninvasive determination of human cortisol and dehydroepiandrosterone sulfate using liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry. 411(6). 1203–1210. 13 indexed citations

Bari, Md. Aynul, Warren B. Kindzierski, & David C. Spink. (2016). Twelve-year trends in ambient concentrations of volatile organic compounds in a community of the Alberta Oil Sands Region, Canada. Environment International. 91. 40–50. 32 indexed citations

D’Agostino, Jaime, Xinxin Ding, Peng Zhang, et al.. (2012). Potential Biological Functions of Cytochrome P450 Reductase-dependent Enzymes in Small Intestine. Journal of Biological Chemistry. 287(21). 17777–17788. 15 indexed citations

Weng, Yan, Fang Xie, Li Xu, et al.. (2010). Analysis of testosterone and dihydrotestosterone in mouse tissues by liquid chromatography–electrospray ionization–tandem mass spectrometry. Analytical Biochemistry. 402(2). 121–128. 27 indexed citations

Xu, Li & David C. Spink. (2007). Analysis of steroidal estrogens as pyridine-3-sulfonyl derivatives by liquid chromatography electrospray tandem mass spectrometry. Analytical Biochemistry. 375(1). 105–114. 85 indexed citations

Spink, Barbara C., et al.. (2006). Inhibition of MCF‐7 breast cancer cell proliferation by MCF‐10A breast epithelial cells in coculture. Cell Biology International. 30(3). 227–238. 30 indexed citations

Spink, David C., et al.. (2004). TCDD and PCBs inhibit breast cancer cell proliferation in vitro. Toxicology in Vitro. 18(6). 811–819. 25 indexed citations

10.

Spink, David C.. (2003). Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells. Carcinogenesis. 24(12). 1941–1950. 57 indexed citations

11.

Spink, Barbara C., Mirza M. Hussain, Barbara H. Katz, Leslie E. Eisele, & David C. Spink. (2003). Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin. Biochemical Pharmacology. 66(12). 2313–2321. 68 indexed citations

12.

Spink, David C., Barbara H. Katz, Mirza M. Hussain, et al.. (2002). Induction of CYP1A1 and CYP1B1 in T-47D Human Breast Cancer Cells by Benzo[a]pyrene Is Diminished by Arsenite. Drug Metabolism and Disposition. 30(3). 262–269. 67 indexed citations

13.

Carpenter, David O., Kathleen F. Arcaro, & David C. Spink. (2002). Understanding the human health effects of chemical mixtures.. Environmental Health Perspectives. 110(suppl 1). 25–42. 312 indexed citations

14.

Spink, David C., Barbara C. Spink, Xiaoliang Zhuo, et al.. (2000). NADPH- and hydroperoxide-supported 17β-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1. The Journal of Steroid Biochemistry and Molecular Biology. 74(1-2). 11–18. 19 indexed citations

15.

Gu, Jun, Carol A. Dudley, Ting Su, et al.. (1999). Cytochrome P450 and Steroid Hydroxylase Activity in Mouse Olfactory and Vomeronasal Mucosa. Biochemical and Biophysical Research Communications. 266(1). 262–267. 23 indexed citations

16.

Spink, David C.. (1998). Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. Carcinogenesis. 19(2). 291–298. 270 indexed citations

17.

Spink, David C., Barbara C. Spink, Joan Cao, et al.. (1997). Induction of cytochrome P450 1B1 and catechol estrogen metabolism in ACHN human renal adenocarcinoma cells. The Journal of Steroid Biochemistry and Molecular Biology. 62(2-3). 223–232. 69 indexed citations

18.

Zhu, Mingshe, David C. Spink, Bin Yan, Shelton Bank, & Anthony P. DeCaprio. (1995). Inhibition of 2,5-Hexanedione-Induced Protein Crosslinking by Biological Thiols: Chemical Mechanisms and Toxicological Implications. Chemical Research in Toxicology. 8(5). 764–771. 18 indexed citations

19.

Obach, R., et al.. (1992). Azidowarfarin photoaffinity probes of purified rat liver cytochrome P4501A1. Archives of Biochemistry and Biophysics. 294(1). 215–222. 11 indexed citations

20.

Spink, David C., Hans‐Pietro Eugster, David W. Lincoln, et al.. (1992). 17β-Estradiol hydroxylation catalyzed by human cytochrome P450 1A1: A comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA. Archives of Biochemistry and Biophysics. 293(2). 342–348. 217 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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