David B. Kastrinsky

1.6k total citations · 1 hit paper
18 papers, 1.1k citations indexed

About

David B. Kastrinsky is a scholar working on Molecular Biology, Organic Chemistry and Toxicology. According to data from OpenAlex, David B. Kastrinsky has authored 18 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 8 papers in Organic Chemistry and 3 papers in Toxicology. Recurrent topics in David B. Kastrinsky's work include Cancer therapeutics and mechanisms (6 papers), Synthetic Organic Chemistry Methods (4 papers) and Bioactive Compounds and Antitumor Agents (3 papers). David B. Kastrinsky is often cited by papers focused on Cancer therapeutics and mechanisms (6 papers), Synthetic Organic Chemistry Methods (4 papers) and Bioactive Compounds and Antitumor Agents (3 papers). David B. Kastrinsky collaborates with scholars based in United States, Sweden and Netherlands. David B. Kastrinsky's co-authors include Dale L. Boger, Goutham Narla, Jaya Sangodkar, Mark S. Tichenor, Clifton E. Barry, Caroline Farrington, Kimberly McClinch, Matthew D. Galsky, Vinod Nair and Elizabeth R. Fischer and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Antimicrobial Agents and Chemotherapy.

In The Last Decade

David B. Kastrinsky

18 papers receiving 1.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis

2012 381 citations Kapil Tahlan, Regina Wilson et al. Antimicrobial Agents and Chemotherapy profile →

Peers

David B. Kastrinsky

EPIDE

ONCOL

Nathan A. Lack Türkiye

Yasunori Muramatsu Japan

Matthieu Desroses Sweden

Jaeseung Kim United States

Daniel Conole United Kingdom

Claudia Jessen‐Trefzer Germany

Barbara Saxty United Kingdom

Olaf Kinzel Italy

Ningyu Wang China

Genbin Shi United States

Nathan A. Lack Türkiye

David B. Kastrinsky

668 ×1.0

166 ×0.5

124 ×0.4

128 ×0.6

EPIDE

169 ×1.9

ONCOL

Citations per year, relative to David B. Kastrinsky David B. Kastrinsky (= 1×) peers Nathan A. Lack

Countries citing papers authored by David B. Kastrinsky

Since Specialization

Citations

This map shows the geographic impact of David B. Kastrinsky's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David B. Kastrinsky with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David B. Kastrinsky more than expected).

Fields of papers citing papers by David B. Kastrinsky

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David B. Kastrinsky. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David B. Kastrinsky. The network helps show where David B. Kastrinsky may publish in the future.

Co-authorship network of co-authors of David B. Kastrinsky

This figure shows the co-authorship network connecting the top 25 collaborators of David B. Kastrinsky. A scholar is included among the top collaborators of David B. Kastrinsky based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David B. Kastrinsky. David B. Kastrinsky is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Denisova, Oxana V., Milena Doroszko, Vadim Le Joncour, et al.. (2020). Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma. Brain Communications. 2(1). fcaa002–fcaa002. 24 indexed citations

Li, Cheuk Wun, Francesca Menconi, Roman Osman, et al.. (2015). Identifying a Small Molecule Blocking Antigen Presentation in Autoimmune Thyroiditis. Journal of Biological Chemistry. 291(8). 4079–4090. 24 indexed citations

Kastrinsky, David B., Jaya Sangodkar, Nilesh Zaware, et al.. (2015). Reengineered tricyclic anti-cancer agents. Bioorganic & Medicinal Chemistry. 23(19). 6528–6534. 55 indexed citations

Sangodkar, Jaya, Caroline Farrington, Kimberly McClinch, et al.. (2015). All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase. FEBS Journal. 283(6). 1004–1024. 234 indexed citations

Avelar, Rita A., David B. Kastrinsky, Michael Ohlmeyer, et al.. (2015). Abstract C132: Therapeutic reactivation of PP2A for prostate cancer treatment. Molecular Cancer Therapeutics. 14(12_Supplement_2). C132–C132. 2 indexed citations

Cooper, Michael R., Agnes Stachnik, David B. Kastrinsky, et al.. (2014). 548 Development of a small molecule activator of protein phosphatase 2A for the treatment of prostate cancer. European Journal of Cancer. 50. 178–178. 1 indexed citations

Sangodkar, Jaya, et al.. (2014). 486 Development of small molecule activators of protein phosphatase 2A for the treatment of lung cancer. European Journal of Cancer. 50. 158–159. 1 indexed citations

Barry, Clifton E., David B. Kastrinsky, Pradeep Kumar, & Gwendolyn A. Marriner. (2012). A Convergent Synthesis of Chiral Diaminopimelic Acid Derived Substrates for Mycobacterial l,d-Transpeptidases. Synthesis. 44(19). 3043–3048. 3 indexed citations

Tahlan, Kapil, Regina Wilson, David B. Kastrinsky, et al.. (2012). SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 56(4). 1797–1809. 381 indexed citations breakdown →

10.

Robertson, W. M., David B. Kastrinsky, Inkyu Hwang, & Dale L. Boger. (2010). Synthesis and evaluation of a series of C5′-substituted duocarmycin SA analogs. Bioorganic & Medicinal Chemistry Letters. 20(9). 2722–2725. 11 indexed citations

11.

Kastrinsky, David B. & Clifton E. Barry. (2009). Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases. Tetrahedron Letters. 51(1). 197–200. 7 indexed citations

12.

Tichenor, Mark S., et al.. (2006). Asymmetric Total Synthesis of (+)- and ent-(−)-Yatakemycin and Duocarmycin SA: Evaluation of Yatakemycin Key Partial Structures and Its Unnatural Enantiomer. Journal of the American Chemical Society. 128(49). 15683–15696. 65 indexed citations

13.

Kastrinsky, David B. & Dale L. Boger. (2004). Effective Asymmetric Synthesis of 1,2,9,9a-Tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI). The Journal of Organic Chemistry. 69(7). 2284–2289. 31 indexed citations

14.

Tichenor, Mark S., David B. Kastrinsky, & Dale L. Boger. (2004). Total Synthesis, Structure Revision, and Absolute Configuration of (+)-Yatakemycin. Journal of the American Chemical Society. 126(27). 8396–8398. 87 indexed citations

15.

Parrish, Jay P., David B. Kastrinsky, Frédéric Stauffer, et al.. (2003). Establishment of substituent effects in the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065. Bioorganic & Medicinal Chemistry. 11(17). 3815–3838. 30 indexed citations

16.

Parrish, Jay P., David B. Kastrinsky, S. E. Wolkenberg, Yasuhiro Igarashi, & Dale L. Boger. (2003). DNA Alkylation Properties of Yatakemycin. Journal of the American Chemical Society. 125(36). 10971–10976. 76 indexed citations

17.

Parrish, Jay P., David B. Kastrinsky, & Dale L. Boger. (2003). Synthesis and X-ray Analysis of an Unprecedented and Stable 2-Aza-4,4-spirocyclopropacyclohexadienone. Organic Letters. 5(14). 2577–2579. 10 indexed citations

18.

Parrish, Jay P., David B. Kastrinsky, Inkyu Hwang, & Dale L. Boger. (2003). Synthesis and Evaluation of Duocarmycin and CC-1065 Analogues Incorporating the 1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]-3-azaindol-4-one (CBA) Alkylation Subunit. The Journal of Organic Chemistry. 68(23). 8984–8990. 11 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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