Darragh P. O’Brien

1.9k total citations
26 papers, 560 citations indexed

About

Darragh P. O’Brien is a scholar working on Molecular Biology, Physiology and Epidemiology. According to data from OpenAlex, Darragh P. O’Brien has authored 26 papers receiving a total of 560 indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 5 papers in Physiology and 4 papers in Epidemiology. Recurrent topics in Darragh P. O’Brien's work include Protein Structure and Dynamics (4 papers), Alzheimer's disease research and treatments (4 papers) and Bacterial Genetics and Biotechnology (4 papers). Darragh P. O’Brien is often cited by papers focused on Protein Structure and Dynamics (4 papers), Alzheimer's disease research and treatments (4 papers) and Bacterial Genetics and Biotechnology (4 papers). Darragh P. O’Brien collaborates with scholars based in United Kingdom, France and United States. Darragh P. O’Brien's co-authors include Sébastien Brier, Alexandre Chenal, Véronique Hourdel, John F. Timms, Julia Chamot‐Rooke, Daniel Ladant, D. Durand, Patrice Vachette, Claire Jenkinson and Evangelia‐Ourania Fourkala and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Bioinformatics.

In The Last Decade

Darragh P. O’Brien

24 papers receiving 556 citations

Peers

Darragh P. O’Brien
Morris A. Kostiuk Canada
Peter Faull United Kingdom
Bettina Mayer Germany
Hongbo Gu United States
Benjamin C. Jennings United States
Georgia Arentz Australia
Giman Jung Japan
Hisao Nagaya Japan
Jun Seop Jeong United States
Annie Bouchard Canada
Morris A. Kostiuk Canada
Darragh P. O’Brien
Citations per year, relative to Darragh P. O’Brien Darragh P. O’Brien (= 1×) peers Morris A. Kostiuk

Countries citing papers authored by Darragh P. O’Brien

Since Specialization
Citations

This map shows the geographic impact of Darragh P. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darragh P. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darragh P. O’Brien more than expected).

Fields of papers citing papers by Darragh P. O’Brien

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darragh P. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darragh P. O’Brien. The network helps show where Darragh P. O’Brien may publish in the future.

Co-authorship network of co-authors of Darragh P. O’Brien

This figure shows the co-authorship network connecting the top 25 collaborators of Darragh P. O’Brien. A scholar is included among the top collaborators of Darragh P. O’Brien based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darragh P. O’Brien. Darragh P. O’Brien is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
O’Brien, Darragh P., Yuqi Shi, Iolanda Vendrell, et al.. (2025). Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor. Journal of Proteome Research. 24(2). 479–490. 4 indexed citations
2.
Maraveyas, Anthony, et al.. (2024). Quantitative proteomics reveals CLR interactome in primary human cells. Journal of Biological Chemistry. 300(6). 107399–107399.
3.
Ellis, Michael J., Darragh P. O’Brien, Shalinee Dhayal, et al.. (2024). Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry. Acta Neuropathologica. 147(1). 87–87. 10 indexed citations
4.
Vowles, Jane, Dayne Beccano-Kelly, M. Irina Stefana, et al.. (2024). Tau depletion in human neurons mitigates Aβ-driven toxicity. Molecular Psychiatry. 29(7). 2009–2020. 7 indexed citations
5.
O’Brien, Darragh P., Zhu Liang, Andreas Damianou, et al.. (2024). Deubiquitinases in muscle physiology and disorders. Biochemical Society Transactions. 52(3). 1085–1098. 3 indexed citations
6.
O’Brien, Darragh P., Emma J. Murphy, Katherine S. England, et al.. (2023). Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides. Molecular & Cellular Proteomics. 22(8). 100609–100609. 16 indexed citations
7.
O’Brien, Darragh P., Adam M. Thorne, Honglei Huang, et al.. (2022). Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model. Clinical Proteomics. 19(1). 6–6. 3 indexed citations
8.
O’Brien, Darragh P., Sylviane Hoos, Sébastien Brûlé, et al.. (2021). A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells. Advanced Science. 8(9). 2003630–2003630. 13 indexed citations
9.
Thorne, Adam M., Honglei Huang, Darragh P. O’Brien, et al.. (2020). Subclinical effects of remote ischaemic conditioning in human kidney transplants revealed by quantitative proteomics. Clinical Proteomics. 17(1). 39–39. 7 indexed citations
10.
O’Brien, Darragh P., Véronique Hourdel, Alexandre Chenal, & Sébastien Brier. (2020). Hydrogen/Deuterium Exchange Mass Spectrometry for the Structural Analysis of Detergent-Solubilized Membrane Proteins. Methods in molecular biology. 2127. 339–358. 9 indexed citations
11.
O’Brien, Darragh P.. (2019). Absolute Zero – Revealing the Void. 4(1). 97–106.
12.
O’Brien, Darragh P., Marilyne Davi, Thibaut Douché, et al.. (2019). Post‐translational acylation controls the folding and functions of the CyaA RTX toxin. The FASEB Journal. 33(9). 10065–10076. 24 indexed citations
13.
O’Brien, Darragh P., Nicolas Sapay, Véronique Yvette Ntsogo Enguéné, et al.. (2018). Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) ofBordetella pertussis. Pathogens and Disease. 76(8). 10 indexed citations
14.
Salladini, Edoardo, Darragh P. O’Brien, Sébastien Brier, et al.. (2017). Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins. Scientific Reports. 7(1). 15544–15544. 43 indexed citations
15.
O’Brien, Darragh P., D. Durand, Véronique Hourdel, et al.. (2017). Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis. PLoS Biology. 15(12). e2004486–e2004486. 27 indexed citations
16.
O’Brien, Darragh P., D. Durand, Véronique Yvette Ntsogo Enguéné, et al.. (2017). Calcium Tightly Regulates Disorder-To-Order Transitions Involved in the Secretion, Folding and Functions of the CyaA Toxin of Bordetella Pertussis, the Causative Agent of Whooping Cough. Biophysical Journal. 112(3). 523a–523a. 1 indexed citations
17.
O’Brien, Darragh P., Sébastien Brier, Daniel Ladant, et al.. (2017). SEC‐SAXS and HDX‐MS: A powerful combination. The case of the calcium‐binding domain of a bacterial toxin. Biotechnology and Applied Biochemistry. 65(1). 62–68. 18 indexed citations
18.
O’Brien, Darragh P., Belén Hernández, D. Durand, et al.. (2015). Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion. Scientific Reports. 5(1). 14223–14223. 47 indexed citations
19.
O’Brien, Darragh P., Neomal S. Sandanayake, Claire Jenkinson, et al.. (2014). Serum CA19-9 Is Significantly Upregulated up to 2 Years before Diagnosis with Pancreatic Cancer: Implications for Early Disease Detection. Clinical Cancer Research. 21(3). 622–631. 147 indexed citations
20.
Güntert, Andreas, James Campbell, Muzamil Saleem, et al.. (2010). Plasma Gelsolin is Decreased and Correlates with Rate of Decline in Alzheimer's Disease. Journal of Alzheimer s Disease. 21(2). 585–596. 64 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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