Constance Brinckerhoff

13.7k total citations · 3 hit papers
151 papers, 11.3k citations indexed

About

Constance Brinckerhoff is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Constance Brinckerhoff has authored 151 papers receiving a total of 11.3k indexed citations (citations by other indexed papers that have themselves been cited), including 89 papers in Molecular Biology, 84 papers in Cancer Research and 39 papers in Oncology. Recurrent topics in Constance Brinckerhoff's work include Protease and Inhibitor Mechanisms (69 papers), Cell Adhesion Molecules Research (31 papers) and Peptidase Inhibition and Analysis (24 papers). Constance Brinckerhoff is often cited by papers focused on Protease and Inhibitor Mechanisms (69 papers), Cell Adhesion Molecules Research (31 papers) and Peptidase Inhibition and Analysis (24 papers). Constance Brinckerhoff collaborates with scholars based in United States, United Kingdom and France. Constance Brinckerhoff's co-authors include Matthew P. Vincenti, Ulrike Benbow, Lynn M. Matrisian, Charles I. Coon, Joni L. Rutter, Edward D. Harris, Teresa I. Mitchell, John A. Mengshol, Lori A. White and Aaron Barchowsky and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Constance Brinckerhoff

150 papers receiving 10.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Matrix metalloproteinases: a tail of a frog that became a prince

2002 918 citations Constance Brinckerhoff et al. profile →
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors

2002 660 citations Matthew P. Vincenti, Constance Brinckerhoff profile →
Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-jun N-terminal kinase, and nuclear factor κB: Differential regulation of collagenase 1 and collagenase 3

2000 557 citations John A. Mengshol, Matthew P. Vincenti et al. Arthritis & Rheumatism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Constance Brinckerhoff United States	58	5.1k	4.8k	3.2k	2.1k	1.5k	151	11.3k
John J. Reynolds United Kingdom	63	5.5k 1.1×	4.3k 0.9×	3.5k 1.1×	2.0k 0.9×	1.8k 1.2×	186	12.6k
Howard G. Welgus United States	70	7.0k 1.4×	3.7k 0.8×	3.7k 1.2×	1.3k 0.6×	2.1k 1.3×	130	14.3k
Veli‐Matti Kähäri Finland	68	6.1k 1.2×	6.8k 1.4×	4.4k 1.4×	981 0.5×	2.3k 1.5×	217	16.1k
Vera Knäuper United Kingdom	52	6.1k 1.2×	3.1k 0.7×	3.7k 1.2×	1.5k 0.7×	1.8k 1.1×	104	9.7k
Renate E. Gay Switzerland	65	2.6k 0.5×	5.5k 1.1×	2.1k 0.7×	3.9k 1.8×	796 0.5×	174	13.4k
Jean‐Marie Delaissé Denmark	55	2.4k 0.5×	5.4k 1.1×	4.0k 1.3×	2.0k 1.0×	579 0.4×	147	9.7k
Katherine A. Hajjar United States	55	3.8k 0.8×	5.7k 1.2×	1.7k 0.6×	950 0.4×	1.0k 0.7×	116	12.0k
Robert Visse United Kingdom	25	3.8k 0.8×	2.6k 0.5×	2.1k 0.7×	775 0.4×	775 0.5×	31	8.3k
Ian M. Clark United Kingdom	42	3.2k 0.6×	2.9k 0.6×	1.3k 0.4×	2.5k 1.2×	673 0.4×	117	7.2k
Maxine Gowen United States	55	1.3k 0.3×	5.6k 1.2×	3.3k 1.1×	2.3k 1.1×	875 0.6×	122	10.0k

Countries citing papers authored by Constance Brinckerhoff

Since Specialization

Citations

This map shows the geographic impact of Constance Brinckerhoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Constance Brinckerhoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Constance Brinckerhoff more than expected).

Fields of papers citing papers by Constance Brinckerhoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Constance Brinckerhoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Constance Brinckerhoff. The network helps show where Constance Brinckerhoff may publish in the future.

Co-authorship network of co-authors of Constance Brinckerhoff

This figure shows the co-authorship network connecting the top 25 collaborators of Constance Brinckerhoff. A scholar is included among the top collaborators of Constance Brinckerhoff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Constance Brinckerhoff. Constance Brinckerhoff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Steinberg, Shannon M., Peisheng Zhang, Brian T. Malik, et al.. (2014). BRAF Inhibition Alleviates Immune Suppression in Murine Autochthonous Melanoma. Cancer Immunology Research. 2(11). 1044–1050. 57 indexed citations

Whipple, Chery A. & Constance Brinckerhoff. (2014). BRAFV600E melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity. British Journal of Cancer. 111(8). 1625–1633. 40 indexed citations

Coon, Charles I., Steven Fiering, Justin Gaudet, Colby A. Wyatt, & Constance Brinckerhoff. (2009). Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP. Matrix Biology. 28(7). 425–431. 11 indexed citations

Hoopes, P. Jack, et al.. (2008). Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model. Breast Cancer Research and Treatment. 116(1). 79–90. 53 indexed citations

Blackburn, Jessica S., C. Harker Rhodes, Charles I. Coon, & Constance Brinckerhoff. (2007). RNA Interference Inhibition of Matrix Metalloproteinase-1 Prevents Melanoma Metastasis by Reducing Tumor Collagenase Activity and Angiogenesis. Cancer Research. 67(22). 10849–10858. 76 indexed citations

Petrella, Brenda L. & Constance Brinckerhoff. (2006). Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.. Molecular Cancer. 5(1). 66–66. 33 indexed citations

Benbow, Ulrike, et al.. (2002). Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1586(3). 265–274. 55 indexed citations

Mengshol, John A., Kimberlee S. Mix, & Constance Brinckerhoff. (2002). Matrix metalloproteinases as therapeutic targets in arthritic diseases: Bull's-eye or missing the mark?. Arthritis & Rheumatism. 46(1). 13–20. 146 indexed citations

Vincenti, Matthew P. & Constance Brinckerhoff. (2001). The potential of signal transduction inhibitors for the treatment of arthritis: is it all just JNK?. Journal of Clinical Investigation. 108(2). 181–183. 10 indexed citations

10.

Noll, Walter W., Dorothy R. Belloni, Joni L. Rutter, et al.. (2001). Loss of Heterozygosity on Chromosome 11q22-23 in Melanoma Is Associated with Retention of the Insertion Polymorphism in the Matrix Metalloproteinase-1 Promoter. American Journal Of Pathology. 158(2). 691–697. 42 indexed citations

11.

Catterall, J., P. J. T. Koshy, B. A. Degnan, et al.. (2001). Synergistic induction of matrix metalloproteinase 1 by interleukin-1? and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism. Arthritis & Rheumatism. 44(10). 2296–2310. 66 indexed citations

12.

Sun, Yubo, Yi Sun, Leonor Wenger, et al.. (1999). Human Metalloproteinase‐1 (Collagenase‐1) Is a Tumor Suppressor Protein p53 Target Gene. Annals of the New York Academy of Sciences. 878(1). 638–641. 12 indexed citations

13.

Mitchell, Teresa I. & Constance Brinckerhoff. (1995). Saturable, high affinity binding of serum amyloid A (SAA ₃ ) to rabbit fibroblasts. Amyloid. 2(2). 83–91. 5 indexed citations

14.

Delany, Anne M. & Constance Brinckerhoff. (1993). The synthetic retinoid (4‐hydroxyphenyl)retinamide decreases collagen expression in vitro and in the tight‐skin mouse. Arthritis & Rheumatism. 36(7). 983–993. 21 indexed citations

15.

Brinckerhoff, Constance. (1990). Retinoids and rheumatoid arthritis: Modulation of extracellular matrix by controlling expression of collagenase. Methods in enzymology on CD-ROM/Methods in enzymology. 190. 175–188. 17 indexed citations

16.

Brinckerhoff, Constance. (1990). Decreased cell proliferation and PGE2 production by fibroblasts treated with a modified hexose sugar, amiprilose hydrochloride. Inflammation Research. 30(3-4). 322–328. 4 indexed citations

17.

Brinckerhoff, Constance, et al.. (1989). Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts. Biochemistry. 28(22). 8691–8698. 93 indexed citations

18.

Phillips, Stephen, et al.. (1988). Induction of collagenase mRNA in lapine articular chondrocytes by synovial factors and interleukin-1. Archives of Biochemistry and Biophysics. 264(1). 351–354. 26 indexed citations

19.

Brinckerhoff, Constance & Martin Lubin. (1978). Increased tumor immunity in mice inoculated with muconomycin A-treated B16 melanoma cells.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 38(11 Pt 1). 3668–72. 5 indexed citations

20.

Brinckerhoff, Constance & Edward D. Harris. (1978). Collagenase production by cultures containing multinucleated cells derived from synovial fibroblasts. Arthritis & Rheumatism. 21(7). 745–753. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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