Christopher D. Link

9.6k total citations · 3 hit papers
80 papers, 6.6k citations indexed

About

Christopher D. Link is a scholar working on Molecular Biology, Aging and Physiology. According to data from OpenAlex, Christopher D. Link has authored 80 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 48 papers in Molecular Biology, 40 papers in Aging and 30 papers in Physiology. Recurrent topics in Christopher D. Link's work include Genetics, Aging, and Longevity in Model Organisms (40 papers), Alzheimer's disease research and treatments (26 papers) and Amyotrophic Lateral Sclerosis Research (9 papers). Christopher D. Link is often cited by papers focused on Genetics, Aging, and Longevity in Model Organisms (40 papers), Alzheimer's disease research and treatments (26 papers) and Amyotrophic Lateral Sclerosis Research (9 papers). Christopher D. Link collaborates with scholars based in United States, Canada and Germany. Christopher D. Link's co-authors include Carolyn J. Johnson, Christine M. Roberts, Thomas E. Johnson, Virginia Fonte, Vishantie Dostal, Servet Yatin, Leonard Petrucelli, D. Allan Butterfield, S. Varadarajan and Yves Christen and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Christopher D. Link

77 papers receiving 6.5k citations

Hit Papers

Expression of human beta-amyloid peptide in transgenic Ca... 1995 2026 2005 2015 1995 2009 2018 100 200 300 400 500
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans.
    1995 539 citations Christopher D. Link Proceedings of the National Academy of Sciences profile →
  2. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
    2009 484 citations Tania F. Gendron, Christopher D. Link et al. Proceedings of the National Academy of Sciences profile →
  3. RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome
    2018 360 citations Briana Van Treeck, David S.W. Protter et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christopher D. Link United States 42 3.2k 2.5k 2.4k 936 670 80 6.6k
Ralf Baumeister Germany 43 3.9k 1.2× 2.3k 0.9× 1.9k 0.8× 255 0.3× 411 0.6× 103 7.0k
Nils J. Færgeman Denmark 45 4.3k 1.3× 561 0.2× 1.2k 0.5× 350 0.4× 166 0.2× 130 6.7k
Laurent Mouchiroud Switzerland 26 3.2k 1.0× 1.2k 0.5× 1.5k 0.6× 171 0.2× 134 0.2× 40 5.4k
Ho Yin Edwin Chan Hong Kong 33 3.2k 1.0× 477 0.2× 680 0.3× 943 1.0× 234 0.3× 125 5.2k
Mariona Jové Spain 38 2.5k 0.8× 335 0.1× 1.5k 0.6× 389 0.4× 144 0.2× 133 4.5k
Walter F. Ward United States 29 2.1k 0.7× 870 0.4× 1.8k 0.8× 132 0.1× 131 0.2× 52 4.5k
Michael T. Lin United States 30 4.7k 1.4× 185 0.1× 3.3k 1.4× 1.1k 1.2× 793 1.2× 38 8.5k
Mark P. Mattson United States 35 2.1k 0.7× 225 0.1× 1.8k 0.8× 278 0.3× 336 0.5× 39 4.9k
Marzia Perluigi Italy 53 3.8k 1.2× 131 0.1× 3.5k 1.5× 417 0.4× 971 1.4× 126 7.7k
Konrad T. Howitz United States 15 2.6k 0.8× 1.3k 0.5× 2.5k 1.0× 49 0.1× 177 0.3× 17 6.6k

Countries citing papers authored by Christopher D. Link

Since Specialization
Citations

This map shows the geographic impact of Christopher D. Link's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher D. Link with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher D. Link more than expected).

Fields of papers citing papers by Christopher D. Link

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher D. Link. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher D. Link. The network helps show where Christopher D. Link may publish in the future.

Co-authorship network of co-authors of Christopher D. Link

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher D. Link. A scholar is included among the top collaborators of Christopher D. Link based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher D. Link. Christopher D. Link is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Link, Christopher D., et al.. (2022). TDP-43 knockdown in mouse model of ALS leads to dsRNA deposition, gliosis, and neurodegeneration in the spinal cord. Cerebral Cortex. 33(10). 5808–5816. 9 indexed citations
3.
Reynolds, Chandra A., Andrew Smolen, Christopher D. Link, et al.. (2022). NEUROFILAMENT LIGHT CHAIN (NFL) AND GENERAL COGNITIVE ABILITY IN ADULTS APPROACHING MIDLIFE. Innovation in Aging. 6(Supplement_1). 807–808. 1 indexed citations
4.
Gonzales, Patrick, Thomas J. LaRocca, Yuping Song, et al.. (2021). Application of a bioinformatic pipeline to RNA-seq data identifies novel virus-like sequence in human blood. G3 Genes Genomes Genetics. 11(9). 5 indexed citations
5.
Dostal, Vishantie & Christopher D. Link. (2021). JoVE Video Dataset.
6.
Link, Christopher D.. (2021). Is There a Brain Microbiome?. SHILAP Revista de lepidopterología. 16. 2288646613–2288646613. 41 indexed citations
7.
Brunt, Vienna E., Thomas J. LaRocca, Zachary J. Sapinsley, et al.. (2020). The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging. GeroScience. 43(1). 377–394. 146 indexed citations
8.
LaRocca, Thomas J., Andrea Mariani, Linda R. Watkins, & Christopher D. Link. (2019). TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes. Neurobiology of Disease. 132. 104514–104514. 40 indexed citations
9.
Treeck, Briana Van, David S.W. Protter, Tyler Matheny, et al.. (2018). RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome. Proceedings of the National Academy of Sciences. 115(11). 2734–2739. 360 indexed citations breakdown →
10.
Munkácsy, Erin, Rebecca Lane, Alex Bokov, et al.. (2016). DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans. PLoS Genetics. 12(7). e1006133–e1006133. 33 indexed citations
11.
Henze, Andrea, Thomas Homann, Michael Aschner, et al.. (2016). Caenorhabditis elegans as a model system to study post-translational modifications of human transthyretin. Scientific Reports. 6(1). 37346–37346. 12 indexed citations
12.
Kokona, Bashkim, C.A. May, Nicole R. Cunningham, et al.. (2015). Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection. Protein Science. 25(3). 605–617. 11 indexed citations
13.
Saldi, Tassa, Peter E.A. Ash, Gavin W. Wilson, et al.. (2014). TDP ‐1, the C aenorhabditis elegans ortholog of TDP ‐43, limits the accumulation of double‐stranded RNA. The EMBO Journal. 33(24). 2947–2966. 52 indexed citations
14.
McColl, Gawain, Aric N. Rogers, Silvestre Alavez, et al.. (2010). Insulin-like Signaling Determines Survival during Stress via Posttranscriptional Mechanisms in C. elegans. Cell Metabolism. 12(3). 260–272. 87 indexed citations
15.
Fonte, Virginia, et al.. (2007). Suppression of in Vivo β-Amyloid Peptide Toxicity by Overexpression of the HSP-16.2 Small Chaperone Protein. Journal of Biological Chemistry. 283(2). 784–791. 128 indexed citations
16.
Link, Christopher D. & Carolyn J. Johnson. (2002). Reporter Transgenes for Study of Oxidant Stress in Caenorhabditis elegans. Methods in enzymology on CD-ROM/Methods in enzymology. 353. 497–505. 75 indexed citations
17.
Fonte, Virginia, et al.. (2002). Interaction of intracellular β amyloid peptide with chaperone proteins. Proceedings of the National Academy of Sciences. 99(14). 9439–9444. 161 indexed citations
18.
19.
Link, Christopher D., Carolyn J. Johnson, Virginia Fonte, et al.. (2001). Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34. Neurobiology of Aging. 22(2). 217–226. 126 indexed citations
20.
Borgonie, Gaëtan, A. Coomans, Dirk De Waele, Edilbert Van Driessche, & Christopher D. Link. (1994). Tissue treatment for whole mount internal lectin staining in the nematodes Caenorhabditis elegans, Panagrolaimus superbus and Acrobeloides maximus. Histochemistry and Cell Biology. 101(5). 379–384. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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