Christine Helsen

2.4k total citations
42 papers, 1.7k citations indexed

About

Christine Helsen is a scholar working on Pulmonary and Respiratory Medicine, Molecular Biology and Genetics. According to data from OpenAlex, Christine Helsen has authored 42 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Pulmonary and Respiratory Medicine, 22 papers in Molecular Biology and 16 papers in Genetics. Recurrent topics in Christine Helsen's work include Prostate Cancer Treatment and Research (23 papers), Hormonal and reproductive studies (15 papers) and Estrogen and related hormone effects (14 papers). Christine Helsen is often cited by papers focused on Prostate Cancer Treatment and Research (23 papers), Hormonal and reproductive studies (15 papers) and Estrogen and related hormone effects (14 papers). Christine Helsen collaborates with scholars based in Belgium, Netherlands and United States. Christine Helsen's co-authors include Frank Claessens, Steven Joniau, Lien Spans, Stefan Preković, Annemie Haelens, Sarah Denayer, Thomas Van den Broeck, Liesbeth Clinckemalie, Stefanie Kerkhofs and Michaël R. Laurent and has published in prestigious journals such as Nucleic Acids Research, Nature Communications and PLoS ONE.

In The Last Decade

Christine Helsen

41 papers receiving 1.7k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christine Helsen Belgium 22 890 720 539 402 289 42 1.7k
Chihuei Wang Taiwan 21 1.0k 1.2× 449 0.6× 453 0.8× 380 0.9× 202 0.7× 43 1.8k
Ramesh Narayanan United States 31 1.2k 1.4× 703 1.0× 699 1.3× 740 1.8× 360 1.2× 84 2.7k
Huei‐Ju Ting United States 22 974 1.1× 444 0.6× 470 0.9× 281 0.7× 313 1.1× 40 1.7k
Daniel E. Frigo United States 27 1.4k 1.5× 484 0.7× 302 0.6× 147 0.4× 788 2.7× 61 2.2k
Yoko Omoto Japan 29 1.1k 1.3× 353 0.5× 1.2k 2.2× 202 0.5× 553 1.9× 49 2.5k
Boris J. Cheskis United States 17 909 1.0× 158 0.2× 1.1k 2.0× 284 0.7× 135 0.5× 18 1.7k
Charles E. Foulds United States 19 1.1k 1.2× 130 0.2× 377 0.7× 104 0.3× 320 1.1× 28 1.7k
Rocio Garcı́a-Becerra Mexico 25 744 0.8× 224 0.3× 323 0.6× 108 0.3× 246 0.9× 74 1.8k
Bunzo Sato Japan 25 1.2k 1.4× 226 0.3× 642 1.2× 633 1.6× 297 1.0× 114 2.3k
Bruno Moncharmont Italy 23 933 1.0× 127 0.2× 624 1.2× 162 0.4× 171 0.6× 46 1.5k

Countries citing papers authored by Christine Helsen

Since Specialization
Citations

This map shows the geographic impact of Christine Helsen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christine Helsen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christine Helsen more than expected).

Fields of papers citing papers by Christine Helsen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christine Helsen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christine Helsen. The network helps show where Christine Helsen may publish in the future.

Co-authorship network of co-authors of Christine Helsen

This figure shows the co-authorship network connecting the top 25 collaborators of Christine Helsen. A scholar is included among the top collaborators of Christine Helsen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christine Helsen. Christine Helsen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Handle, Florian, Elien Smeets, Lisa Moris, et al.. (2024). Rational evolution for altering the ligand preference of estrogen receptor alpha. Protein Science. 33(4). e4940–e4940. 1 indexed citations
3.
Helsen, Christine, Joice Thomas, Steven Joniau, et al.. (2024). Discovery of a novel androgen receptor antagonist, MEL-6, with stereoselective activity and optimization of its metabolic stability. The Journal of Steroid Biochemistry and Molecular Biology. 239. 106476–106476. 1 indexed citations
4.
Helsen, Christine, Maria Santa Rocca, Cinzia Vinanzi, et al.. (2023). Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer. Protein Science. 32(4). e4599–e4599. 4 indexed citations
5.
Helsen, Christine, et al.. (2022). The T850D Phosphomimetic Mutation in the Androgen Receptor Ligand Binding Domain Enhances Recruitment at Activation Function 2. International Journal of Molecular Sciences. 23(3). 1557–1557. 4 indexed citations
6.
Helsen, Christine, Nikolaos Louros, Joost Schymkowitz, et al.. (2022). Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors. Molecular Cancer Therapeutics. 21(12). 1823–1834. 9 indexed citations
7.
Smeets, Elien, Erika Van Nieuwenhove, Christine Helsen, et al.. (2022). A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer. Journal of Cachexia Sarcopenia and Muscle. 13(4). 2242–2253. 14 indexed citations
8.
Schöne, Stefanie, Stefan Preković, Isabel Mayayo‐Peralta, et al.. (2021). Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites. Nucleic Acids Research. 49(7). 3856–3875. 18 indexed citations
9.
Helsen, Christine, et al.. (2021). Structure and stability of the designer protein WRAP-T and its permutants. Scientific Reports. 11(1). 18867–18867. 2 indexed citations
10.
Szafran, Adam T., Michael J. Bolt, Maureen G. Mancini, et al.. (2020). A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals. SLAS DISCOVERY. 25(7). 695–708. 3 indexed citations
11.
Quevedo, Mario A., Leentje Persoons, Christophe Pannecouque, et al.. (2018). Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents. Bioorganic & Medicinal Chemistry Letters. 28(21). 3472–3476. 71 indexed citations
12.
Claessens, Frank, Steven Joniau, & Christine Helsen. (2017). Comparing the rules of engagement of androgen and glucocorticoid receptors. Cellular and Molecular Life Sciences. 74(12). 2217–2228. 52 indexed citations
13.
Preković, Stefan, Thomas Van den Broeck, Lisa Moris, et al.. (2017). Treatment-induced changes in the androgen receptor axis: Liquid biopsies as diagnostic/prognostic tools for prostate cancer. Molecular and Cellular Endocrinology. 462(Pt A). 56–63. 13 indexed citations
14.
Preković, Stefan, Martin E. van Royen, Arnout Voet, et al.. (2016). The Effect of F877L and T878A Mutations on Androgen Receptor Response to Enzalutamide. Molecular Cancer Therapeutics. 15(7). 1702–1712. 80 indexed citations
15.
Laurent, Michaël R., Christine Helsen, Leen Antonio, et al.. (2016). Effects of sex hormone-binding globulin (SHBG) on androgen bioactivity in vitro. Molecular and Cellular Endocrinology. 437. 280–291. 27 indexed citations
16.
Broeck, Thomas Van den, Steven Joniau, Liesbeth Clinckemalie, et al.. (2014). The Role of Single Nucleotide Polymorphisms in Predicting Prostate Cancer Risk and Therapeutic Decision Making. BioMed Research International. 2014. 1–16. 39 indexed citations
17.
Claessens, Frank, Christine Helsen, Stefan Preković, et al.. (2014). Emerging mechanisms of enzalutamide resistance in prostate cancer. Nature Reviews Urology. 11(12). 712–716. 107 indexed citations
18.
Clinckemalie, Liesbeth, Lien Spans, Vanessa Dubois, et al.. (2013). Androgen Regulation of the TMPRSS2 Gene and the Effect of a SNP in an Androgen Response Element. Molecular Endocrinology. 27(12). 2028–2040. 98 indexed citations
19.
Voet, Arnout, Christine Helsen, Kam Y. J. Zhang, & Frank Claessens. (2013). The Discovery of Novel Human Androgen Receptor Antagonist Chemotypes Using a Combined Pharmacophore Screening Procedure. ChemMedChem. 8(4). 644–651. 24 indexed citations
20.
Helsen, Christine, Arnaud Marchand, Patrick Chaltin, et al.. (2012). Identification and Characterization of MEL-3, a Novel AR Antagonist That Suppresses Prostate Cancer Cell Growth. Molecular Cancer Therapeutics. 11(6). 1257–1268. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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