Chi-Chao Chan

6.7k total citations · 2 hit papers
93 papers, 4.9k citations indexed

About

Chi-Chao Chan is a scholar working on Ophthalmology, Immunology and Rheumatology. According to data from OpenAlex, Chi-Chao Chan has authored 93 papers receiving a total of 4.9k indexed citations (citations by other indexed papers that have themselves been cited), including 52 papers in Ophthalmology, 36 papers in Immunology and 21 papers in Rheumatology. Recurrent topics in Chi-Chao Chan's work include Ocular Diseases and Behçet’s Syndrome (33 papers), Systemic Lupus Erythematosus Research (20 papers) and Retinal Diseases and Treatments (17 papers). Chi-Chao Chan is often cited by papers focused on Ocular Diseases and Behçet’s Syndrome (33 papers), Systemic Lupus Erythematosus Research (20 papers) and Retinal Diseases and Treatments (17 papers). Chi-Chao Chan collaborates with scholars based in United States, China and United Kingdom. Chi-Chao Chan's co-authors include Rachel R Caspi, Phyllis B. Silver, Nicholas P. Restifo, Steven A. Rosenberg, Deborah R. Surman, Willem W. Overwijk, Rafael S. Grajewski, Jun Tang, Douglas C. Palmer and Christopher A. Klebanoff and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

In The Last Decade

Chi-Chao Chan

93 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells

2005 585 citations Paul A. Antony, Ciriaco A. Piccirillo et al. The Journal of Immunology profile →
Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

2015 299 citations Reiko Horai, Carlos R. Zárate-Bladés et al. Immunity profile →

Peers

Countries citing papers authored by Chi-Chao Chan

Since Specialization

Citations

This map shows the geographic impact of Chi-Chao Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chi-Chao Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chi-Chao Chan more than expected).

Fields of papers citing papers by Chi-Chao Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chi-Chao Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chi-Chao Chan. The network helps show where Chi-Chao Chan may publish in the future.

Co-authorship network of co-authors of Chi-Chao Chan

This figure shows the co-authorship network connecting the top 25 collaborators of Chi-Chao Chan. A scholar is included among the top collaborators of Chi-Chao Chan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chi-Chao Chan. Chi-Chao Chan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Human βA3/A1-crystallin splicing mutation causes cataracts by activating the unfolded protein response and inducing apoptosis in differentiating lens fiber cells 2016 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Zhiwei Ma, Wenliang Yao, Chi-Chao Chan, Chitra Kannabiran, Eric F. Wawrousek, J. Fielding Hejtmancik	20
2	Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site breakdown → 2015 ·Immunity ·Reiko Horai, Carlos R. Zárate-Bladés, Patrícia Dillenburg-Pilla, Jun Chen, Jennifer L. Kielczewski, Phyllis B. Silver, Yingyos Jittayasothorn, Chi-Chao Chan, Hidehiro Yamane, Kenya Honda, Rachel R Caspi	299
3	IL-10 -1082 SNP and IL-10 in primary CNS and vitreoretinal lymphomas 2012 ·Graefe s Archive for Clinical and Experimental Ophthalmology ·Hema L. Ramkumar, De Fen Shen, Jingsheng Tuo, Rita M. Braziel, Sarah E. Coupland, Justine R. Smith, Chi-Chao Chan	19
4	Anti-inflammatory recombinant TSG-6 stabilizes the progression of focal retinal degeneration in a murine model 2012 ·Journal of Neuroinflammation ·Jingsheng Tuo, Xiaoguang Cao, Defen Shen, Yujuan Wang, Jun Zhang, Joo Youn Oh, Darwin J. Prockop, Chi-Chao Chan	33
5	Evolution of Cellular Inclusions in Bietti’s Crystalline Dystrophy 2010 ·PubMed ·Chi-Chao Chan, (unknown), (unknown)	12
6	Hydrodynamic Vaccination with DNA Encoding an Immunologically Privileged Retinal Antigen Protects from Autoimmunity through Induction of Regulatory T Cells 2007 ·The Journal of Immunology ·Phyllis B. Silver, Rajeev Agarwal, (unknown), Isabelle Suffia, Rafael S. Grajewski, Dror Luger, Chi-Chao Chan, Rashid M. Mahdi, John M. Nickerson, Rachel R Caspi	29
7	Autoimmune Uveitis Elicited with Antigen-Pulsed Dendritic Cells Has a Distinct Clinical Signature and Is Driven by Unique Effector Mechanisms: Initial Encounter with Autoantigen Defines Disease Phenotype 2007 ·The Journal of Immunology ·Jun Tang, Wei Zhu, Phyllis B. Silver, (unknown), Chi-Chao Chan, Rachel R Caspi	78
8	Altered Chemokine Profile Associated with Exacerbated Autoimmune Pathology under Conditions of Genetic Interferon-γ Deficiency 2007 ·Investigative Ophthalmology & Visual Science ·Shao Bo Su, Rafael S. Grajewski, Dror Luger, Rajeev Agarwal, Phyllis B. Silver, Jun Tang, Jingsheng Tuo, Chi-Chao Chan, Rachel R Caspi	50
9	Eradication of Tumor Colonization and Invasion by a B Cell–Specific Immunotoxin in a Murine Model for Human Primary Intraocular Lymphoma 2006 ·Cancer Research ·Zhuqing Li, Sankaranarayana P. Mahesh, De Fen Shen, Baoying Liu, Willie O. Siu, Frank S. Hwang, (unknown), Chi-Chao Chan, Ira Pastan, Robert B. Nussenblatt	22
10	Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity 2006 ·The Journal of Experimental Medicine ·Rafael S. Grajewski, Phyllis B. Silver, Rajeev Agarwal, (unknown), Chi-Chao Chan, Gregory I. Liou, Rachel R Caspi	69
11	Human cytomegalovirus induced cyclooxygenase-2 in human retinal pigment epithelial cells augments viral replication through a prostaglandin pathway 2006 ·Microbes and Infection ·John J. Hooks, Marian S. Chin, Kumar Srinivasan, (unknown), Laura C. Hooper, Chandrasekharam N. Nagineni, Chi-Chao Chan, Barbara Detrick	25
12	CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells breakdown → 2005 ·The Journal of Immunology ·Paul A. Antony, Ciriaco A. Piccirillo, Akgül Akpınarlı, Steven E. Finkelstein, (unknown), Deborah R. Surman, Douglas C. Palmer, Chi-Chao Chan, Christopher A. Klebanoff, Willem W. Overwijk, Steven A. Rosenberg, Nicholas P. Restifo	585
13	Essential Role of the MyD88 Pathway, but Nonessential Roles of TLRs 2, 4, and 9, in the Adjuvant Effect Promoting Th1-Mediated Autoimmunity 2005 ·The Journal of Immunology ·Shao Bo Su, Phyllis B. Silver, Rafael S. Grajewski, Rajeev Agarwal, Jun Tang, Chi-Chao Chan, Rachel R Caspi	115
14	Cholera Toxin Prevents Th1-Mediated Autoimmune Disease by Inducing Immune Deviation 2004 ·The Journal of Immunology ·(unknown), Phyllis B. Silver, Peng Wang, Chi-Chao Chan, Rachel R Caspi	21
15	A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice 2003 ·Journal of Clinical Investigation ·Giuseppina Pennesi, Mary J. Mattapallil, (unknown), Dody Avichezer, Phyllis B. Silver, Zaruhi Karabekian, Chella S. David, Paul A. Hargrave, J. Hugh McDowell, W. Clay Smith, Barbara Wiggert, Larry A. Donoso, Chi-Chao Chan, Rachel R Caspi	74
16	Dissociating the Enhancing and Inhibitory Effects of Pertussis Toxin on Autoimmune Disease 2003 ·The Journal of Immunology ·Shao Bo Su, Phyllis B. Silver, Peng Wang, Chi-Chao Chan, Rachel R Caspi	10
17	Pertussis toxin alters the innate and the adaptive immune responses in a pertussis-dependent model of autoimmunity 2002 ·Journal of Neuroimmunology ·Rajeev Agarwal, (unknown), Shao Bo Su, Chi-Chao Chan, Rachel R Caspi	28
18	Conjunctival Epithelial Cells Cultured on Human Amniotic Membrane Fail to Transdifferentiate into Corneal Epithelial-Type Cells 1999 ·Cornea ·(unknown), Ali R. Djalilian, Wesley F. Obritsch, (unknown), Chi-Chao Chan, Edward J. Holland	39
19	Immunohistochemical Examination of Lacrimal Gland Tissue from Patients with Ocular Sarcoidosis 1998 ·Advances in experimental medicine and biology ·Janine A. Smith, Chi-Chao Chan, Charles E. Egwuagu, Scott M. Whitcup	4
20	Monoclonal antibodies against CD54 (ICAM-1) and CD11a (LFA-1) prevent and inhibit endotoxin-induced uveitis 1995 ·Experimental Eye Research ·Scott M. Whitcup, Naofumi Hikita, M Shirao, Masayuki Miyasaka, Takuya Tamatani, Manabu Mochizuki, R. B. Nussenblatt, Chi-Chao Chan	50

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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