Reiko Horai

9.1k total citations · 3 hit papers
93 papers, 7.5k citations indexed

About

Reiko Horai is a scholar working on Immunology, Molecular Biology and Rheumatology. According to data from OpenAlex, Reiko Horai has authored 93 papers receiving a total of 7.5k indexed citations (citations by other indexed papers that have themselves been cited), including 52 papers in Immunology, 26 papers in Molecular Biology and 22 papers in Rheumatology. Recurrent topics in Reiko Horai's work include T-cell and B-cell Immunology (21 papers), Ocular Diseases and Behçet’s Syndrome (20 papers) and Systemic Lupus Erythematosus Research (18 papers). Reiko Horai is often cited by papers focused on T-cell and B-cell Immunology (21 papers), Ocular Diseases and Behçet’s Syndrome (20 papers) and Systemic Lupus Erythematosus Research (18 papers). Reiko Horai collaborates with scholars based in United States, Japan and China. Reiko Horai's co-authors include Yoichiro Iwakura, Masahide Asano, Katsuko Sudo, Rachel R Caspi, Susumu Nakae, Shinobu Saijo, Nancy J. Rothwell, R.A. LeFeuvre, Hervé Boutin and Taizo Matsuki and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Reiko Horai

91 papers receiving 7.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice

2000 596 citations Reiko Horai, Shinobu Saijo et al. The Journal of Experimental Medicine profile →
Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion

1998 530 citations Reiko Horai, Masahide Asano et al. The Journal of Experimental Medicine profile →
Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

2015 299 citations Reiko Horai, Carlos R. Zárate-Bladés et al. Immunity profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Reiko Horai United States	44	3.9k	2.3k	1.0k	917	864	93	7.5k
Abdolmohamad Rostami United States	51	5.5k 1.4×	1.9k 0.8×	566 0.6×	626 0.7×	1.3k 1.5×	185	9.4k
Edgar Meinl Germany	56	5.0k 1.3×	2.7k 1.2×	1.8k 1.8×	1.1k 1.2×	2.0k 2.3×	151	11.8k
Thomas A. Ferguson United States	43	3.9k 1.0×	3.3k 1.4×	1.5k 1.5×	220 0.2×	567 0.7×	84	8.4k
William A. Kuziel United States	67	7.7k 2.0×	3.1k 1.3×	2.1k 2.1×	505 0.6×	1.3k 1.5×	125	13.9k
Cheng‐Rong Yu United States	41	3.0k 0.8×	1.5k 0.6×	444 0.4×	689 0.8×	193 0.2×	86	6.0k
Estelle Bettelli United States	24	9.0k 2.3×	1.6k 0.7×	857 0.9×	1.0k 1.1×	617 0.7×	36	11.8k
Christine D. Dijkstra Netherlands	55	4.0k 1.0×	2.6k 1.1×	608 0.6×	492 0.5×	2.6k 3.0×	132	9.7k
Bao Lu United States	60	6.5k 1.7×	2.3k 1.0×	1.6k 1.6×	543 0.6×	802 0.9×	126	12.4k
John J. Hooks United States	43	1.9k 0.5×	1.6k 0.7×	968 1.0×	918 1.0×	295 0.3×	118	5.7k
Rick A. Wetsel United States	51	5.3k 1.3×	1.8k 0.8×	863 0.9×	1.0k 1.1×	819 0.9×	126	8.9k

Countries citing papers authored by Reiko Horai

Since Specialization

Citations

This map shows the geographic impact of Reiko Horai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Reiko Horai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Reiko Horai more than expected).

Fields of papers citing papers by Reiko Horai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Reiko Horai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Reiko Horai. The network helps show where Reiko Horai may publish in the future.

Co-authorship network of co-authors of Reiko Horai

This figure shows the co-authorship network connecting the top 25 collaborators of Reiko Horai. A scholar is included among the top collaborators of Reiko Horai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Reiko Horai. Reiko Horai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Nagarajan, Vijayaraj, Jing Guo, Akriti Gupta, et al.. (2025). TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming. The Journal of Experimental Medicine. 222(11).

Xu, Biying, Jihong Tang, Cancan Lyu, et al.. (2021). Regulated Tristetraprolin Overexpression Dampens the Development and Pathogenesis of Experimental Autoimmune Uveitis. Frontiers in Immunology. 11. 583510–583510. 6 indexed citations

Chong, Wai Po, Mary J. Mattapallil, Kumarkrishna Raychaudhuri, et al.. (2020). The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24. Immunity. 53(2). 384–397.e5. 137 indexed citations

Horai, Reiko, et al.. (2017). Gut microbiota as a source of signals that trigger spontaneous ocular autoimmunity. 6–15. 1 indexed citations

Zárate-Bladés, Carlos R., Reiko Horai, & Rachel R Caspi. (2016). Regulation of Autoimmunity by the Microbiome. DNA and Cell Biology. 35(9). 455–458. 17 indexed citations

Kielczewski, Jennifer L., Reiko Horai, & Rachel R Caspi. (2012). Migration of retina-specific T Cells into the eye of optic nerve injured mice. Investigative Ophthalmology & Visual Science. 53(14). 4270–4270.

Zhou, Ru, Reiko Horai, Phyllis B. Silver, et al.. (2012). The Living Eye “Disarms” Uncommitted Autoreactive T Cells by Converting Them to Foxp3+ Regulatory Cells following Local Antigen Recognition. The Journal of Immunology. 188(4). 1742–1750. 76 indexed citations

Chaon, Benjamin, Reiko Horai, Jun Chen, et al.. (2012). The Role of Interleukin-17A in a Spontaneous Model of Autoimmune Uveitis Elicited by Retina-specific T Cells. Investigative Ophthalmology & Visual Science. 53(14). 6307–6307. 1 indexed citations

Horai, Reiko & Rachel R Caspi. (2011). Cytokines in Autoimmune Uveitis. Journal of Interferon & Cytokine Research. 31(10). 733–744. 142 indexed citations

10.

Caspi, Rachel R, Reiko Horai, Jun Chen, et al.. (2011). Retina-specific T regulatory cells accumulate in the eye during autoimmune uveitis and act to control inflammation (115.22). The Journal of Immunology. 186(1_Supplement). 115.22–115.22. 2 indexed citations

11.

Rachitskaya, Aleksandra, Anna M. Hansen, Reiko Horai, et al.. (2008). Cutting Edge: NKT Cells Constitutively Express IL-23 Receptor and RORγt and Rapidly Produce IL-17 upon Receptor Ligation in an IL-6-Independent Fashion. The Journal of Immunology. 180(8). 5167–5171. 335 indexed citations

12.

Agarwal, Rajeev, Reiko Horai, Angelia Viley, et al.. (2008). Abrogation of Anti-Retinal Autoimmunity in IL-10 Transgenic Mice Due to Reduced T Cell Priming and Inhibition of Disease Effector Mechanisms. The Journal of Immunology. 180(8). 5423–5429. 26 indexed citations

13.

Chiba, Shuichi, Masatoshi Suzuki, Takefumi Kikusui, et al.. (2007). Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene. Behavioural Brain Research. 185(2). 110–118. 137 indexed citations

14.

Broussard, Christine, Christine Fleischacker, Reiko Horai, et al.. (2006). Altered Development of CD8+ T Cell Lineages in Mice Deficient for the Tec Kinases Itk and Rlk. Immunity. 25(5). 849–849. 7 indexed citations

15.

Horai, Reiko, Akiko Nakajima, Katsuyoshi Habiro, et al.. (2004). TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist–deficient mice. Journal of Clinical Investigation. 114(11). 1603–1611. 100 indexed citations

16.

Ohtaki, Hirokazu, Yin Li, Kenji Dohi, et al.. (2003). Suppression of oxidative stress after transient focal ischemia in interleukin-1 knock out mice. PubMed. 86. 191–194. 25 indexed citations

17.

Ohtaki, Hirokazu, Hisayuki Funahashi, Kenji Dohi, et al.. (2003). Suppression of oxidative neuronal damage after transient middle cerebral artery occlusion in mice lacking interleukin-1. Neuroscience Research. 45(3). 313–324. 44 indexed citations

18.

Oguro, Takiko, Yuko Takahashi, Takashi Ashino, et al.. (2002). Involvement of tumor necrosis factor α, rather than interleukin‐1α/β or nitric oxides in the heme oxygenase‐1 gene expression by lipopolysaccharide in the mouse liver. FEBS Letters. 516(1-3). 63–66. 33 indexed citations

19.

Nakae, Susumu, Masahide Asano, Reiko Horai, Nobuo Sakaguchi, & Yoichiro Iwakura. (2001). IL-1 Enhances T Cell-Dependent Antibody Production Through Induction of CD40 Ligand and OX40 on T Cells. The Journal of Immunology. 167(1). 90–97. 108 indexed citations

20.

Yamada, Hiroyuki, et al.. (2000). Protective Role of Interleukin-1 in Mycobacterial Infection in IL-1 α/β Double-Knockout Mice. Laboratory Investigation. 80(5). 759–767. 172 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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