Catherine Higgins

468 total citations
21 papers, 350 citations indexed

About

Catherine Higgins is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Catherine Higgins has authored 21 papers receiving a total of 350 indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 6 papers in Oncology and 4 papers in Cancer Research. Recurrent topics in Catherine Higgins's work include Cell death mechanisms and regulation (10 papers), Ubiquitin and proteasome pathways (4 papers) and Cancer-related Molecular Pathways (3 papers). Catherine Higgins is often cited by papers focused on Cell death mechanisms and regulation (10 papers), Ubiquitin and proteasome pathways (4 papers) and Cancer-related Molecular Pathways (3 papers). Catherine Higgins collaborates with scholars based in United Kingdom, Ireland and Canada. Catherine Higgins's co-authors include Daniel B. Longley, Nyree Crawford, Joanna Majkut, Patrick G. Johnston, Christopher J. Scott, Christian Bailly, Angela Seaton, John Mann, Henk van den Berg and Timothy Harrison and has published in prestigious journals such as Nature Communications, Cancer Research and Cell Death and Differentiation.

In The Last Decade

Catherine Higgins

20 papers receiving 331 citations

Peers

Catherine Higgins
Małgorzata Kajstura United States
Jianxia Guo United States
Seung Yeob Hyun South Korea
Mir Mohd Faheem India
Christine Basmadjian France
Jagannath Pal United States
Lei-Chin Chen Taiwan
Elin Lindhagen Sweden
Mao Tian China
Małgorzata Kajstura United States
Catherine Higgins
Citations per year, relative to Catherine Higgins Catherine Higgins (= 1×) peers Małgorzata Kajstura

Countries citing papers authored by Catherine Higgins

Since Specialization
Citations

This map shows the geographic impact of Catherine Higgins's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Catherine Higgins with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Catherine Higgins more than expected).

Fields of papers citing papers by Catherine Higgins

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Catherine Higgins. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Catherine Higgins. The network helps show where Catherine Higgins may publish in the future.

Co-authorship network of co-authors of Catherine Higgins

This figure shows the co-authorship network connecting the top 25 collaborators of Catherine Higgins. A scholar is included among the top collaborators of Catherine Higgins based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Catherine Higgins. Catherine Higgins is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Davidovich, Pavel B., et al.. (2023). cFLIPL acts as a suppressor of TRAIL- and Fas-initiated inflammation by inhibiting assembly of caspase-8/FADD/RIPK1 NF-κB-activating complexes. Cell Reports. 42(12). 113476–113476. 22 indexed citations
2.
Longley, Daniel B., et al.. (2021). Therapeutics Targeting the Core Apoptotic Machinery. Cancers. 13(11). 2618–2618. 12 indexed citations
3.
Higgins, Catherine, Jamie Z. Roberts, Declan Doherty, et al.. (2021). Abstract 1342: Development and preclinical evaluation of unique first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP. Cancer Research. 81(13_Supplement). 1342–1342. 3 indexed citations
4.
Ray, Suprio, et al.. (2020). Enabling NUMA-aware Main Memory Spatial Join Processing: An Experimental Study.. Very Large Data Bases. 1–8.
5.
Higgins, Catherine, Joanna Majkut, Tamas Sessler, et al.. (2020). A revised model of TRAIL ‐R2 DISC assembly explains how FLIP (L) can inhibit or promote apoptosis. EMBO Reports. 21(3). e49254–e49254. 40 indexed citations
6.
Longley, Daniel B., Catherine Higgins, Jamie Z. Roberts, et al.. (2020). Abstract 5220: Development of first-in-class small molecule inhibitors of FLIP which activate caspase-8, the nodal regulator of apoptosis, necroptosis and pyroptosis. Cancer Research. 80(16_Supplement). 5220–5220. 3 indexed citations
7.
Roberts, Jamie Z., Caitriona Holohan, Tamas Sessler, et al.. (2020). The SCFSkp2 ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L). Cell Death and Differentiation. 27(9). 2726–2741. 20 indexed citations
8.
Higgins, Catherine, Joanna Majkut, Jamie Z. Roberts, et al.. (2019). Abstract 382: Development and pre-clinical assessment of a first-in-class small molecule inhibitor of FLIP. Cancer Research. 79(13_Supplement). 382–382. 2 indexed citations
9.
Higgins, Catherine, Joanna Majkut, Trevor R. Perrior, et al.. (2018). Abstract B129: Development and preclinical assessment of a first-in-class small-molecule inhibitor of FLIP. Molecular Cancer Therapeutics. 17(1_Supplement). B129–B129. 1 indexed citations
10.
Majkut, Joanna, et al.. (2017). Abstract LB-305: Development and pre-clinical assessment of a first-in-class small molecule inhibitor of FLIP. Cancer Research. 77(13_Supplement). LB–305. 1 indexed citations
11.
Bradley, Conor A., Joanna Majkut, Catherine Higgins, et al.. (2016). FLIP: A Targetable Mediator of Resistance to Radiation in Non–Small Cell Lung Cancer. Molecular Cancer Therapeutics. 15(10). 2432–2441. 19 indexed citations
12.
Higgins, Catherine, Joanna Majkut, Margarita Espona‐Fiedler, et al.. (2016). Development and pre-clinical assessment of a first-in-class small molecule inhibitor of FLIP for treatment of NSCLC and CRC. European Journal of Cancer. 69. S6–S6. 2 indexed citations
13.
Eddie, Sharon L., Catherine Higgins, Zenobia D’Costa, et al.. (2015). Development of a potent and selective cell penetrant Legumain inhibitor. Bioorganic & Medicinal Chemistry Letters. 25(23). 5642–5645. 15 indexed citations
14.
Majkut, Joanna, Miriam Sgobba, Caitriona Holohan, et al.. (2014). Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly. Nature Communications. 5(1). 3350–3350. 64 indexed citations
15.
Higgins, Catherine, Zenobia D’Costa, Martin O’Rourke, et al.. (2014). P3 SAR exploration of biphenyl carbamate based Legumain inhibitors. Bioorganic & Medicinal Chemistry Letters. 24(11). 2521–2524. 9 indexed citations
16.
D’Costa, Zenobia, Catherine Higgins, Chee Wee Ong, et al.. (2014). TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.. Oncotarget. 5(6). 1609–1620. 36 indexed citations
17.
Higgins, Catherine, et al.. (2010). Growth Inhibitory Activity of Extracted Material and Isolated Compounds from the Fruits ofKigelia pinnata. Planta Medica. 76(16). 1840–1846. 26 indexed citations
18.
19.
Seaton, Angela, Catherine Higgins, John Mann, et al.. (2003). Mechanistic and anti-proliferative studies of two novel, biologically active bis-benzimidazoles. European Journal of Cancer. 39(17). 2548–2555. 39 indexed citations
20.
Higgins, Catherine. (1991). I Have a Dream in Washington, D.C. Initial Report.. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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