Casey Cook

8.7k citations

44 papers · 4.0k · 4 hit papers · h-index 28

Impact in

Neurology top 0.5%
- Amyotrophic Lateral Sclerosis Research
- Parkinson's Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
Physiology top 1%
- Alzheimer's disease research and treatments

Papers in

Physiology 22
- Alzheimer's disease research and treatments 21
Molecular Biology 20
- RNA Research and Splicing 5

Co-authors: Leonard Petrucelli (36 shared papers)Dennis W. Dickson (21 shared papers)Yari Carlomagno (12 shared papers)Caroline Stetler (4 shared papers)Michael DeTure (11 shared papers)Tania F. Gendron (7 shared papers)Monica Castanedes‐Casey (8 shared papers)Karen Jansen‐West (9 shared papers)
Journals: Human Molecular Genetics (5 papers)Acta Neuropathologica Communications (4 papers)Molecular Neurodegeneration (4 papers)PLoS ONE (3 papers)Nature Neuroscience (2 papers)
Partner nations: United States United Kingdom Italy

In The Last Decade

Casey Cook

44 papers receiving 3.9k citations

Hit Papers

align trajectories log scale

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains 2020 · 293 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Cell
2016 Acta Neuropathologica Communications
2016 Nature Neuroscience
2009 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Casey Cook

Since Specialization

Citations

This map shows the geographic impact of Casey Cook's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Casey Cook with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Casey Cook more than expected).

Fields of papers citing papers by Casey Cook

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Casey Cook. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Casey Cook. The network helps show where Casey Cook may publish in the future.

Co-authors

The 25 scholars most cited alongside Casey Cook, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Casey Cook Line = papers co-authored together Casey Cook links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 44 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Neuronal activity enhances tau propagation and tau pathology in vivo Nature Neuroscience ·Jessica Wu, S. Abid Hussaini, Isle Bastille, G Rodriguez, Ana Mrejeru, Kelly C. Rilett, David W. Sanders, Casey Cook, Hongjun Fu, Rick A.C.M. Boonen, Mathieu Herman, Eden Nahmani, Sheina Emrani, Yvette H. Figueroa, Marc I. Diamond, Catherine L. Clelland, Selina Wray, Karen Duff Hit paper breakdown →	2016	574
2	Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity Proceedings of the National Academy of Sciences ·Yong‐Jie Zhang, Ya-Fei Xu, Casey Cook, Tania F. Gendron, Paul S. Roettges, Christopher D. Link, Wen-Lang Lin, Jimei Tong, Monica Castanedes‐Casey, Peter E.A. Ash, Jennifer Gass, Vijayaraghavan Rangachari, Emanuele Buratti, Francisco E. Baralle, Todd E. Golde, Dennis W. Dickson, Leonard Petrucelli Hit paper breakdown →	2009	484
3	An autoradiographic evaluation of AV-1451 Tau PET in dementia Acta Neuropathologica Communications ·Val J. Lowe, Geoffry L. Curran, Ping Fang, Amanda M. Liesinger, Keith A. Josephs, Joseph E. Parisi, Kejal Kantarci, Bradley F. Boeve, Mukesh K. Pandey, Tyler J. Bruinsma, David S. Knopman, David T. Jones, Leonard Petrucelli, Casey Cook, Neill R. Graff‐Radford, Dennis W. Dickson, Ronald C. Petersen, Clifford R. Jack, Melissa E. Murray Hit paper breakdown →	2016	348
4	Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains Cell ·Tamta Arakhamia, Christina E. Lee, Yari Carlomagno, Mukesh Kumar, Duc M. Duong, Hendrik Wesseling, Sean R. Kundinger, Kevin Wang, Dewight Williams, Michael DeTure, Dennis W. Dickson, Casey Cook, Nicholas T. Seyfried, Leonard Petrucelli, Judith A. Steen, Anthony W. P. Fitzpatrick Hit paper breakdown →	2020	293
5	Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity Cell Reports ·Tara Vanderweyde, Daniel J. Apicco, Katherine Youmans-Kidder, Peter E.A. Ash, Casey Cook, Edroaldo Lummertz da Rocha, Karen Jansen‐West, Alissa A. Frame, Allison Citro, John Leszyk, Pavel Ivanov, Jose F. Abisambra, Martín Steffen, Hu Li, Leonard Petrucelli, Benjamin Wolozin	2016	243
6	Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance Human Molecular Genetics ·Casey Cook, Yari Carlomagno, Tania F. Gendron, Judy H. Dunmore, Kristyn Scheffel, Caroline Stetler, Mary Dabney Davis, Dennis W. Dickson, Matthew Jarpe, Michael DeTure, Leonard Petrucelli	2013	225
7	Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau The Journal of Experimental Medicine ·Silvia S. Kang, Mark Ebbert, Kelsey E. Baker, Casey Cook, Xuewei Wang, Jonathon Sens, Jeanne-Pierre Kocher, Leonard Petrucelli, John Denis Fryer	2018	164
8	Progranulin regulates neuronal outgrowth independent of Sortilin Molecular Neurodegeneration ·Jennifer Gass, Chris W. Lee, Casey Cook, NiCole A. Finch, Caroline Stetler, Karen Jansen‐West, Jada Lewis, Christopher D. Link, Rosa Rademakers, Anders Nykjær, Leonard Petrucelli	2012	118
9	Disruption of Protein Quality Control in Parkinson's Disease Cold Spring Harbor Perspectives in Medicine ·Casey Cook, Caroline Stetler, Leonard Petrucelli	2012	115
10	Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation Human Molecular Genetics ·Casey Cook, Tania F. Gendron, Kristyn Scheffel, Yari Carlomagno, Judy H. Dunmore, Michael DeTure, Leonard Petrucelli	2012	110
11	Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy Molecular Neurodegeneration ·Jeannie Chew, Casey Cook, Tania F. Gendron, Karen Jansen‐West, Giulia del Rosso, Lillian M. Daughrity, Monica Castanedes‐Casey, Aishe Kurti, Jeannette N. Stankowski, Matthew D. Disney, Jeffrey D. Rothstein, Dennis W. Dickson, John Denis Fryer, Yong-Jie Zhang, Leonard Petrucelli	2019	104
12	An acetylation–phosphorylation switch that regulates tau aggregation propensity and function Journal of Biological Chemistry ·Yari Carlomagno, Dah-eun Chloe Chung, Mei Yue, Monica Castanedes‐Casey, Benjamin J. Madden, Judy H. Dunmore, Jimei Tong, Michael DeTure, Dennis W. Dickson, Leonard Petrucelli, Casey Cook	2017	99
13	Acetylation: a new key to unlock tau’s role in neurodegeneration Alzheimer s Research & Therapy ·Casey Cook, Jeannette N. Stankowski, Yari Carlomagno, Caroline Stetler, Leonard Petrucelli	2014	98
14	Genetic Convergence Brings Clarity to the Enigmatic Red Line in ALS Neuron ·Casey Cook, Leonard Petrucelli	2019	88
15	A critical evaluation of the ubiquitin–proteasome system in Parkinson's disease Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Casey Cook, Leonard Petrucelli	2009	86
16	Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients Human Molecular Genetics ·Mercedes Prudencio, Patrick Gonzales, Casey Cook, Tania F. Gendron, Lillian M. Daughrity, Yuping Song, Mark Ebbert, Marka van Blitterswijk, Yong‐Jie Zhang, Karen Jansen‐West, Matthew Baker, Michael DeTure, Rosa Rademakers, Khrista Boylan, Dennis W. Dickson, Leonard Petrucelli, Christopher D. Link	2017	73
17	The lysosomal protein cathepsin L is a progranulin protease Molecular Neurodegeneration ·Chris W. Lee, Jeannette N. Stankowski, Jeannie Chew, Casey Cook, Ying‐Wai Lam, Sandra Almeida, Yari Carlomagno, Kwok‐Fai Lau, Mercedes Prudencio, Fen‐Biao Gao, Matthew Bogyo, Dennis W. Dickson, Leonard Petrucelli	2017	70
18	Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD Nature Neuroscience ·Lindsey D. Goodman, Mercedes Prudencio, Nicholas J. Kramer, Luis F. Martinez-Ramirez, Ananth Srinivasan, Matthews Lan, Michael Parisi, Yongqing Zhu, Jeannie Chew, Casey Cook, Amit Berson, Aaron D. Gitler, Leonard Petrucelli, Nancy M. Bonini	2019	57
19	Expression of calcipressin1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease Journal of Alzheimer s Disease ·Casey Cook, Matthew J. Hejna, Debra J. Magnuson, John M. Lee	2005	56
20	TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor Human Molecular Genetics ·Fatemeh Mohagheghi, Mercedes Prudencio, Cristiana Stuani, Casey Cook, Karen Jansen‐West, Dennis W. Dickson, Leonard Petrucelli, Emanuele Buratti	2015	54

About Casey Cook

Casey Cook is a scholar working on Physiology, Molecular Biology, Neurology, Cellular and Molecular Neuroscience and Neurology, having authored 44 papers that have together received 4.0k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (21 papers), Amyotrophic Lateral Sclerosis Research (13 papers), Parkinson's Disease Mechanisms and Treatments (10 papers), Neurogenetic and Muscular Disorders Research (6 papers), Cholinesterase and Neurodegenerative Diseases (6 papers), RNA Research and Splicing (5 papers), Neuroscience and Neuropharmacology Research (5 papers) and Neurological diseases and metabolism (4 papers). The work is most often cited by research in Neurology (1.5k citations), Neurology (691 citations), Physiology (1.9k citations), Genetics (454 citations) and Cellular and Molecular Neuroscience (745 citations). Casey Cook has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Leonard Petrucelli, Dennis W. Dickson, Yari Carlomagno, Caroline Stetler, Michael DeTure, Tania F. Gendron, Monica Castanedes‐Casey, Karen Jansen‐West, Judy H. Dunmore and Yong‐Jie Zhang. Their work appears in journals such as Human Molecular Genetics, Acta Neuropathologica Communications, Molecular Neurodegeneration, PLoS ONE and Nature Neuroscience.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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