Brian R. de Costa

3.2k citations

74 papers · 2.7k indexed · h-index 28

Cellular and Molecular Neuroscience top 0.5%
Molecular Biology top 5%
Pharmacology top 2%
Organic Chemistry top 5%
Physiology

Co-authors: Wayne D. Bowen Kenner C. Rice Richard B. Rothman Miles Herkenham Eric K. Richfield Rae R. Matsumoto Lilian Radesca Arthur E. Jacobson
Topics: Pharmacological Receptor Mechanisms and Effects (38 papers)Receptor Mechanisms and Signaling (31 papers)Neuropeptides and Animal Physiology (23 papers)
Cited by: Cellular and Molecular Neuroscience Pharmacology Molecular Biology
Journals: Brain Research FEBS Letters Journal of Medicinal Chemistry
Partner nations: United States Czechia Hungary

In The Last Decade

Brian R. de Costa

74 papers receiving 2.7k citations

Peers

Countries citing papers authored by Brian R. de Costa

Since Specialization

Citations

This map shows the geographic impact of Brian R. de Costa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian R. de Costa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian R. de Costa more than expected).

Fields of papers citing papers by Brian R. de Costa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian R. de Costa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian R. de Costa. The network helps show where Brian R. de Costa may publish in the future.

Co-authorship network of co-authors of Brian R. de Costa

This figure shows the co-authorship network connecting the top 25 collaborators of Brian R. de Costa. A scholar is included among the top collaborators of Brian R. de Costa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian R. de Costa. Brian R. de Costa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting σ1 receptors produce anti-cocaine effects in mice 2001 ·European Journal of Pharmacology ·Rae R. Matsumoto,(unknown),(unknown),Buddy Pouw,Brian R. de Costa,Wayne D. Bowen	63
2	N-alkyl substituted analogs of the σ receptor ligand BD1008 and traditional σ receptor ligands affect cocaine-induced convulsions and lethality in mice 2001 ·European Journal of Pharmacology ·Rae R. Matsumoto,(unknown),Buddy Pouw,Jeffrey M. Miller,Wayne D. Bowen,(unknown),Brian R. de Costa	56
3	Subchronic administration of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine (BD1047) alters σ1 receptor binding 1997 ·European Journal of Pharmacology ·Alexander C. Zambon,Brian R. de Costa,Anumantha G. Kanthasamy,(unknown),Rae R. Matsumoto	14
4	Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: Preliminary evidence for different binding domains 1994 ·Neurochemical Research ·Christina M. Dersch,Hyacinth C. Akunne,John S. Partilla,(unknown),Brian R. de Costa,Kenner C. Rice,F. Ivy Carroll,(unknown)	30
5	Central administration of the endopeptidase 24.15 inhibitor cFP-AAF-pAB suggests dynorphin as the endogenous ligand underlying behavioral effects of milk in the fetal rat 1994 ·Pharmacology Biochemistry and Behavior ·William P. Smotherman,Scott R. Robinson,Elena I. Varlinskaya,Evgeniy S. Petrov,(unknown),Brian R. de Costa,Kenner C. Rice	12
6	Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologs at dopamine-uptake and phencyclidine-, and .sigma.-binding sites 1993 ·Journal of Medicinal Chemistry ·(unknown),Lionel P. Raymon,Mariena V. Mattson,Mohyee E. Eldefrawi,Brian R. de Costa	17
7	Selective labeling of κ2 opioid receptors in rat brain by [125I]IOXY: Interaction of opioid peptides and other drugs with multiple κ2a binding sites 1993 ·Peptides ·Qing Zhe Ni,Heng Xu,John S. Partilla,Brian R. de Costa,Kenner C. Rice,Richard B. Rothman	25
8	Identification of a GBR12935 homolog, LR1111, which is over 4,000‐fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters 1993 ·Synapse ·Richard B. Rothman,Bruce Lewis,(unknown),Heng Xu,(unknown),Brian R. de Costa,Kenner C. Rice,(unknown),Hyacinth C. Akunne,Agu Pert	69
9	Probes for narcotic receptor mediated phenomena. 18. Epimeric 6.alpha.- and 6.beta.-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5.alpha.-epoxymorphinans as potential ligands for opioid receptor single photon emission computed tomography: synthesis, evaluation, and radiochemistry of [125I]-6.beta.-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5.alpha.-epoxymorphinan 1992 ·Journal of Medicinal Chemistry ·Brian R. de Costa,Michael J. Iadarola,(unknown),Karen F. Berman,C. George,Amy Hauck Newman,Artin Mahboubi,Arthur E. Jacobson,(unknown)	26
10	Interaction of opioid peptides and other drugs with multiple δncx binding sites in rat brain: Further evidence for heterogeneity 1992 ·Peptides ·Heng Xu,John S. Partilla,Brian R. de Costa,Kenner C. Rice,(unknown)	13
11	Synthesis of [³H]tert‐butyl 8‐chloro‐5,6‐dihydro‐5‐methyl‐6‐oxo‐4h‐imidazo[1,5‐a][1,4]benzodiazepine 3‐carboxylate, a selective, high affinity ligand for the diazepam insensitive (DI) subtype of the benzodiazepine receptor 1992 ·Journal of Labelled Compounds and Radiopharmaceuticals ·(unknown),Brian R. de Costa,Garry Wong,Kenner C. Rice,Phil Skolnick	5
12	Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor 1992 ·Journal of Medicinal Chemistry ·Brian R. de Costa,Lilian Radesca,(unknown),Wayne D. Bowen	56
13	Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter 1992 ·Pharmacology Biochemistry and Behavior ·Richard B. Rothman,(unknown),(unknown),Brian R. de Costa,Kenner C. Rice,F. Ivy Carroll,Agu Pert	72
14	Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences 1992 ·Peptides ·Richard B. Rothman,Victor Bykov,(unknown),H. Y. Xu,Brian R. de Costa,Arthur E. Jacobson,Kenner C. Rice,Joel E. Kleinman,Linda S. Brady	41
15	MPTP lesions of the nigrostriatal dopaminergic projection decrease [3H]1-[1-(2-thienyl)cyclohexyl]-piperidine binding to PCP site 2: Further evidence that PCP site 2 is associated with the biogenic amine reuptake complex 1992 ·Neurochemical Research ·Hyacinth C. Akunne,Jan N. Johannessen,Brian R. de Costa,Kenner C. Rice,Richard B. Rothman	8
16	Drug specificity of pharmacological dystonia 1990 ·Pharmacology Biochemistry and Behavior ·Rae R. Matsumoto,(unknown),(unknown),Andrew Thurkauf,Brian R. de Costa,Kenner C. Rice,Susan B. Hellewell,Wayne D. Bowen,James M. Walker	83
17	Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain 1990 ·Peptides ·Richard B. Rothman,Victor Bykov,Brian R. de Costa,Arthur E. Jacobson,Kenner C. Rice,Linda S. Brady	130
18	Selective and enantiospecific acylation of .kappa.-opioid receptors by (1S,2S)-trans-2-isothiocyanato-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide. Demonstration of .kappa. receptor heterogeneity 1989 ·Journal of Medicinal Chemistry ·Brian R. de Costa,(unknown),Victor Bykov,Arthur E. Jacobson,Kenner C. Rice	27
19	Synthesis of an affinity ligand (‘UPHIT’) for in vivo acylation of the κ‐opioid receptor 1989 ·FEBS Letters ·Brian R. de Costa,Linda C. Band,Richard B. Rothman,Arthur E. Jacobson,Victor Bykov,Agu Pert,Kenner C. Rice	10
20	Synthesis, configuration, and evaluation of two conformationally restrained analogs of phencyclidine 1988 ·Journal of Medicinal Chemistry ·Brian R. de Costa,Clifford George,Terrence R. Burke,Michael Rafferty,Patricia C. Contreras,(unknown),Arthur E. Jacobson,Kenner C. Rice	6

About Brian R. de Costa

Brian R. de Costa is a scholar working on Cellular and Molecular Neuroscience, Organic Chemistry and Molecular Biology, having authored 74 papers that have together received 2.7k indexed citations. Recurring topics across this work include Pharmacological Receptor Mechanisms and Effects (38 papers), Receptor Mechanisms and Signaling (31 papers) and Neuropeptides and Animal Physiology (23 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.9k citations), Pharmacology (495 citations) and Molecular Biology (1.8k citations). Brian R. de Costa has collaborated with scholars based in United States, Czechia and Hungary. Frequent co-authors include Wayne D. Bowen, Kenner C. Rice, Richard B. Rothman, Miles Herkenham, Eric K. Richfield, Rae R. Matsumoto, Lilian Radesca, Arthur E. Jacobson, Andrew Thurkauf and Daniel Truong. Their work appears in journals such as Brain Research, FEBS Letters and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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