Brian R. de Costa

3.2k citations

74 papers · 2.7k indexed · h-index 28

Cellular and Molecular Neuroscience top 0.5%
- Neuropeptides and Animal Physiology 23
- Neuroscience and Neuropharmacology Research 18
- Neurotransmitter Receptor Influence on Behavior 11
Pharmacology top 2%
Molecular Biology top 5%
- Pharmacological Receptor Mechanisms and Effects 38
- Receptor Mechanisms and Signaling 31
- Phenothiazines and Benzothiazines Synthesis and Activities 8
- Chemical Synthesis and Analysis 6
Biological Psychiatry top 10%
Toxicology top 5%
Organic Chemistry
- Synthesis and Biological Evaluation 8

Co-authors: Wayne D. Bowen Kenner C. Rice Richard B. Rothman Miles Herkenham Eric K. Richfield Rae R. Matsumoto Lilian Radesca Arthur E. Jacobson
Cited by: Cellular and Molecular Neuroscience Pharmacology Molecular Biology
Journals: Brain Research (1 paper)FEBS Letters (2 papers)Journal of Medicinal Chemistry (20 papers)
Partner nations: United States Czechia Hungary

In The Last Decade

Brian R. de Costa

74 papers receiving 2.7k citations

Peers

Countries citing papers authored by Brian R. de Costa

Since Specialization

Citations

This map shows the geographic impact of Brian R. de Costa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian R. de Costa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian R. de Costa more than expected).

Fields of papers citing papers by Brian R. de Costa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian R. de Costa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian R. de Costa. The network helps show where Brian R. de Costa may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Brian R. de Costa, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian R. de Costa Line = papers co-authored together Brian R. de Costa links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting σ1 receptors produce anti-cocaine effects in mice European Journal of Pharmacology ·Rae R. Matsumoto,Kari A. McCracken,Michele J Friedman,Buddy Pouw,Brian R. de Costa,Wayne D. Bowen	2001	63
2	N-alkyl substituted analogs of the σ receptor ligand BD1008 and traditional σ receptor ligands affect cocaine-induced convulsions and lethality in mice European Journal of Pharmacology ·Rae R. Matsumoto,Kari A. McCracken,Buddy Pouw,Jeffrey M. Miller,Wayne D. Bowen,Wanda Williams,Brian R. de Costa	2001	56
3	Subchronic administration of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine (BD1047) alters σ1 receptor binding European Journal of Pharmacology ·Alexander C. Zambon,Brian R. de Costa,Anumantha G. Kanthasamy,Bang Q.H Nguyen,Rae R. Matsumoto	1997	14
4	Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: Preliminary evidence for different binding domains Neurochemical Research ·Christina M. Dersch,Hyacinth C. Akunne,John S. Partilla,George U. Char,Brian R. de Costa,Kenner C. Rice,F. Ivy Carroll,Richard B. Rothman	1994	30
5	Central administration of the endopeptidase 24.15 inhibitor cFP-AAF-pAB suggests dynorphin as the endogenous ligand underlying behavioral effects of milk in the fetal rat Pharmacology Biochemistry and Behavior ·William P. Smotherman,Scott R. Robinson,Elena I. Varlinskaya,Evgeniy S. Petrov,Marion Orlowski,Brian R. de Costa,Kenner C. Rice	1994	12
6	Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologs at dopamine-uptake and phencyclidine-, and .sigma.-binding sites Journal of Medicinal Chemistry ·Xiao Shu He,Lionel P. Raymon,Mariena V. Mattson,Mohyee E. Eldefrawi,Brian R. de Costa	1993	17
7	Selective labeling of κ2 opioid receptors in rat brain by [125I]IOXY: Interaction of opioid peptides and other drugs with multiple κ2a binding sites Peptides ·Qing Zhe Ni,Heng Xu,John S. Partilla,Brian R. de Costa,Kenner C. Rice,Richard B. Rothman	1993	25
8	Identification of a GBR12935 homolog, LR1111, which is over 4,000‐fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters Synapse ·Richard B. Rothman,Bruce Lewis,Chris Dersch,Heng Xu,Lillian R. Radesca,Brian R. de Costa,Kenner C. Rice,Robert B. Kilburn,Hyacinth C. Akunne,Agu Pert	1993	69
9	Probes for narcotic receptor mediated phenomena. 18. Epimeric 6.alpha.- and 6.beta.-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5.alpha.-epoxymorphinans as potential ligands for opioid receptor single photon emission computed tomography: synthesis, evaluation, and radiochemistry of [125I]-6.beta.-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5.alpha.-epoxymorphinan Journal of Medicinal Chemistry ·Brian R. de Costa,Michael J. Iadarola,Richard B. Rothman,Karen F. Berman,C. George,Amy Hauck Newman,Artin Mahboubi,Arthur E. Jacobson,Kenner C. Rice	1992	26
10	Interaction of opioid peptides and other drugs with multiple δncx binding sites in rat brain: Further evidence for heterogeneity Peptides ·Heng Xu,John S. Partilla,Brian R. de Costa,Kenner C. Rice,Richard B. Rothman	1992	13
11	Synthesis of [³H]tert‐butyl 8‐chloro‐5,6‐dihydro‐5‐methyl‐6‐oxo‐4h‐imidazo[1,5‐a][1,4]benzodiazepine 3‐carboxylate, a selective, high affinity ligand for the diazepam insensitive (DI) subtype of the benzodiazepine receptor Journal of Labelled Compounds and Radiopharmaceuticals ·Zi‐Qiang Gu,Brian R. de Costa,Garry Wong,Kenner C. Rice,Phil Skolnick	1992	5
12	Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor Journal of Medicinal Chemistry ·Brian R. de Costa,Lilian Radesca,Lisa Di Paolo,Wayne D. Bowen	1992	56
13	Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter Pharmacology Biochemistry and Behavior ·Richard B. Rothman,Nigel H. Grieg,Andrew Kim,Brian R. de Costa,Kenner C. Rice,F. Ivy Carroll,Agu Pert	1992	72
14	Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences Peptides ·Richard B. Rothman,Victor Bykov,Bowen Xue,H. Y. Xu,Brian R. de Costa,Arthur E. Jacobson,Kenner C. Rice,Joel E. Kleinman,Linda S. Brady	1992	41
15	MPTP lesions of the nigrostriatal dopaminergic projection decrease [3H]1-[1-(2-thienyl)cyclohexyl]-piperidine binding to PCP site 2: Further evidence that PCP site 2 is associated with the biogenic amine reuptake complex Neurochemical Research ·Hyacinth C. Akunne,Jan N. Johannessen,Brian R. de Costa,Kenner C. Rice,Richard B. Rothman	1992	8
16	Drug specificity of pharmacological dystonia Pharmacology Biochemistry and Behavior ·Rae R. Matsumoto,Mitzi K. Hemstreet,Naline L. Lai,Andrew Thurkauf,Brian R. de Costa,Kenner C. Rice,Susan B. Hellewell,Wayne D. Bowen,James M. Walker	1990	83
17	Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain Peptides ·Richard B. Rothman,Victor Bykov,Brian R. de Costa,Arthur E. Jacobson,Kenner C. Rice,Linda S. Brady	1990	130
18	Selective and enantiospecific acylation of .kappa.-opioid receptors by (1S,2S)-trans-2-isothiocyanato-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide. Demonstration of .kappa. receptor heterogeneity Journal of Medicinal Chemistry ·Brian R. de Costa,Richard B. Rothman,Victor Bykov,Arthur E. Jacobson,Kenner C. Rice	1989	27
19	Synthesis of an affinity ligand (‘UPHIT’) for in vivo acylation of the κ‐opioid receptor FEBS Letters ·Brian R. de Costa,Linda C. Band,Richard B. Rothman,Arthur E. Jacobson,Victor Bykov,Agu Pert,Kenner C. Rice	1989	10
20	Synthesis, configuration, and evaluation of two conformationally restrained analogs of phencyclidine Journal of Medicinal Chemistry ·Brian R. de Costa,Clifford George,Terrence R. Burke,Michael Rafferty,Patricia C. Contreras,Stephen J. Mick,Arthur E. Jacobson,Kenner C. Rice	1988	6

About Brian R. de Costa

Brian R. de Costa is a scholar working on Cellular and Molecular Neuroscience, Organic Chemistry and Molecular Biology, having authored 74 papers that have together received 2.7k indexed citations. Recurring topics across this work include Pharmacological Receptor Mechanisms and Effects (38 papers), Receptor Mechanisms and Signaling (31 papers), Neuropeptides and Animal Physiology (23 papers), Neuroscience and Neuropharmacology Research (18 papers), Neurotransmitter Receptor Influence on Behavior (11 papers), Phenothiazines and Benzothiazines Synthesis and Activities (8 papers), Synthesis and Biological Evaluation (8 papers) and Chemical Synthesis and Analysis (6 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.9k citations), Pharmacology (495 citations) and Molecular Biology (1.8k citations). Brian R. de Costa has collaborated with scholars based in United States, Czechia and Hungary. Frequent co-authors include Wayne D. Bowen, Kenner C. Rice, Richard B. Rothman, Miles Herkenham, Eric K. Richfield, Rae R. Matsumoto, Lilian Radesca, Arthur E. Jacobson, Andrew Thurkauf and Daniel Truong. Their work appears in journals such as Brain Research, FEBS Letters and Journal of Medicinal Chemistry.

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