Barbara Sedgwick

7.1k total citations · 3 hit papers
43 papers, 4.6k citations indexed

About

Barbara Sedgwick is a scholar working on Molecular Biology, Genetics and Cancer Research. According to data from OpenAlex, Barbara Sedgwick has authored 43 papers receiving a total of 4.6k indexed citations (citations by other indexed papers that have themselves been cited), including 38 papers in Molecular Biology, 15 papers in Genetics and 11 papers in Cancer Research. Recurrent topics in Barbara Sedgwick's work include DNA Repair Mechanisms (33 papers), Epigenetics and DNA Methylation (17 papers) and Bacterial Genetics and Biotechnology (14 papers). Barbara Sedgwick is often cited by papers focused on DNA Repair Mechanisms (33 papers), Epigenetics and DNA Methylation (17 papers) and Bacterial Genetics and Biotechnology (14 papers). Barbara Sedgwick collaborates with scholars based in United Kingdom, United States and France. Barbara Sedgwick's co-authors include Tomas Lindahl, Sarah C. Trewick, Peter Robins, Yusaku Nakabeppu, Timothy F. Henshaw, Robert P. Hausinger, Paul A. Bates, Pertti Koivisto, Tod Duncan and Ian Teo and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Barbara Sedgwick

43 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

2002 617 citations Sarah C. Trewick, Timothy F. Henshaw et al. Nature profile →
REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 562 citations Barbara Sedgwick, Yusaku Nakabeppu et al. Annual Review of Biochemistry profile →
Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

2009 294 citations Barbara Sedgwick, Tomas Lindahl et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Barbara Sedgwick United Kingdom	30	4.0k	1.1k	973	325	299	43	4.6k
Richard P. Cunningham United States	46	6.8k 1.7×	1.7k 1.5×	738 0.8×	86 0.3×	636 2.1×	104	7.7k
Binghui Shen United States	47	5.9k 1.5×	819 0.7×	897 0.9×	132 0.4×	918 3.1×	145	6.6k
F.K. Winkler Switzerland	18	2.5k 0.6×	385 0.3×	467 0.5×	97 0.3×	432 1.4×	32	4.1k
Masaru Takeshita Japan	27	3.8k 1.0×	416 0.4×	1.0k 1.1×	79 0.2×	768 2.6×	71	5.0k
W. Dean Rupp United States	32	5.0k 1.3×	2.5k 2.2×	815 0.8×	56 0.2×	585 2.0×	67	6.0k
Akane Kawamura United Kingdom	36	3.4k 0.9×	268 0.2×	1.1k 1.2×	161 0.5×	350 1.2×	101	4.5k
T.H. Tahirov United States	31	3.2k 0.8×	952 0.8×	217 0.2×	58 0.2×	401 1.3×	115	4.0k
Sheila S. David United States	40	5.0k 1.3×	601 0.5×	888 0.9×	187 0.6×	1.1k 3.6×	103	6.3k
James C. Delaney United States	29	2.3k 0.6×	278 0.2×	507 0.5×	135 0.4×	211 0.7×	43	2.7k
Robert P. Fuchs France	53	7.6k 1.9×	2.3k 2.0×	2.4k 2.4×	47 0.1×	621 2.1×	182	8.3k

Countries citing papers authored by Barbara Sedgwick

Since Specialization

Citations

This map shows the geographic impact of Barbara Sedgwick's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barbara Sedgwick with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barbara Sedgwick more than expected).

Fields of papers citing papers by Barbara Sedgwick

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barbara Sedgwick. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barbara Sedgwick. The network helps show where Barbara Sedgwick may publish in the future.

Co-authorship network of co-authors of Barbara Sedgwick

This figure shows the co-authorship network connecting the top 25 collaborators of Barbara Sedgwick. A scholar is included among the top collaborators of Barbara Sedgwick based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Barbara Sedgwick. Barbara Sedgwick is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bleijlevens, Boris, Emily Flashman, Yi Yang, et al.. (2008). Dynamic states of the DNA repair enzyme AlkB regulate product release. EMBO Reports. 9(9). 872–877. 52 indexed citations

Bleijlevens, Boris, et al.. (2007). Replacement of non-heme Fe(II) with Cu(II) in the α-ketoglutarate dependent DNA repair enzyme AlkB: Spectroscopic characterization of the active site. Journal of Inorganic Biochemistry. 101(7). 1043–1048. 15 indexed citations

Sedgwick, Barbara, Peter Robins, & Tomas Lindahl. (2006). Direct Removal of Alkylation Damage from DNA by AlkB and Related DNA Dioxygenases. Methods in enzymology on CD-ROM/Methods in enzymology. 408. 108–120. 22 indexed citations

Sedgwick, Barbara, Paul A. Bates, Johanna Paik, Stacy L. Jacobs, & Tomas Lindahl. (2006). Repair of alkylated DNA: Recent advances. DNA repair. 6(4). 429–442. 253 indexed citations

Paik, Johanna, Tod Duncan, Tomas Lindahl, & Barbara Sedgwick. (2005). Sensitization of Human Carcinoma Cells to Alkylating Agents by Small Interfering RNA Suppression of 3-Alkyladenine-DNA Glycosylase. Cancer Research. 65(22). 10472–10477. 50 indexed citations

Sedgwick, Barbara. (2004). Repairing DNA-methylation damage. Nature Reviews Molecular Cell Biology. 5(2). 148–157. 283 indexed citations

Koivisto, Pertti, Peter Robins, Tomas Lindahl, & Barbara Sedgwick. (2004). Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases. Journal of Biological Chemistry. 279(39). 40470–40474. 87 indexed citations

Koivisto, Pertti, Tod Duncan, Tomas Lindahl, & Barbara Sedgwick. (2003). Minimal Methylated Substrate and Extended Substrate Range of Escherichia coli AlkB Protein, a 1-Methyladenine-DNA Dioxygenase. Journal of Biological Chemistry. 278(45). 44348–44354. 69 indexed citations

Trewick, Sarah C., Timothy F. Henshaw, Robert P. Hausinger, Tomas Lindahl, & Barbara Sedgwick. (2002). Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage. Nature. 419(6903). 174–178. 617 indexed citations breakdown →

10.

Duncan, Tod, Sarah C. Trewick, Pertti Koivisto, et al.. (2002). Reversal of DNA alkylation damage by two human dioxygenases. Proceedings of the National Academy of Sciences. 99(26). 16660–16665. 320 indexed citations

11.

Trewick, Sarah C., et al.. (2000). Defective processing of methylated single-stranded DNA by E. coli alkB mutants. Genes & Development. 14(16). 2097–2105. 104 indexed citations

12.

Sedgwick, Barbara. (1997). Nitrosated peptides and polyamines as endogenous mutagens in O6- alkylguanine-DNA alkyltransferase deficient cells. Carcinogenesis. 18(8). 1561–1567. 61 indexed citations

13.

Roldán‐Arjona, Teresa & Barbara Sedgwick. (1996). DNA base damage induced by ionizing radiation recognized byEscherichia coli UvrABC nuclease but not Nth or Fpg proteins. Molecular Carcinogenesis. 16(4). 188–196. 11 indexed citations

14.

Dianov, Grigory L., Barbara Sedgwick, Graham Daly, et al.. (1994). Release of 5′-terminal deoxyribose-phosphate residues from incised abasic sites in DNA by theEscherichia coliRecJ protein. Nucleic Acids Research. 22(6). 993–998. 85 indexed citations

15.

Barnes, Deborah E., Tomas Lindahl, & Barbara Sedgwick. (1993). DNA repair. Current Opinion in Cell Biology. 5(3). 424–433. 58 indexed citations

16.

Vaughan, Patrick, Tomas Lindahl, & Barbara Sedgwick. (1993). Induction of the adaptive response of Escherichia coli to alkylation damage by the environmental mutagen, methyl chloride. Mutation Research/DNA Repair. 293(3). 249–257. 19 indexed citations

17.

Vaughan, P, Barbara Sedgwick, J. Hall, Julian Gannon, & Tomas Lindahl. (1991). Environmental mutagens that induce the adaptive response to alkylating agents in Escherichia coli. Carcinogenesis. 12(2). 263–268. 38 indexed citations

18.

Sedgwick, Barbara & Patrick Vaughan. (1991). Widespread adaptive response against environmental methylating agents in microorganisms. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 250(1-2). 211–221. 38 indexed citations

19.

Sedgwick, Barbara, et al.. (1988). REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS. Annual Review of Biochemistry. 57(1). 133–157. 562 indexed citations breakdown →

20.

Cairns, John, Peter Robins, Barbara Sedgwick, & Philippa J. Talmud. (1981). The Inducible Repair of Alkylated DNA. Progress in nucleic acid research and molecular biology. 26. 237–244. 62 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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