Allan C. Spradling

47.7k total citations · 15 hit papers
183 papers, 32.3k citations indexed

About

Allan C. Spradling is a scholar working on Molecular Biology, Genetics and Plant Science. According to data from OpenAlex, Allan C. Spradling has authored 183 papers receiving a total of 32.3k indexed citations (citations by other indexed papers that have themselves been cited), including 138 papers in Molecular Biology, 54 papers in Genetics and 44 papers in Plant Science. Recurrent topics in Allan C. Spradling's work include Genomics and Chromatin Dynamics (35 papers), Developmental Biology and Gene Regulation (35 papers) and Chromosomal and Genetic Variations (32 papers). Allan C. Spradling is often cited by papers focused on Genomics and Chromatin Dynamics (35 papers), Developmental Biology and Gene Regulation (35 papers) and Chromosomal and Genetic Variations (32 papers). Allan C. Spradling collaborates with scholars based in United States, United Kingdom and Canada. Allan C. Spradling's co-authors include Gerald M. Rubin, Benjamin Ohlstein, Sean J. Morrison, Haifan Lin, Toshie Kai, Daniela Drummond‐Barbosa, Ting Xie, Melissa E. Pepling, Margaret de Cuevas and Gary H. Karpen and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Allan C. Spradling

179 papers receiving 31.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 2.6k citations Allan C. Spradling et al. Science profile →
Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

2008 1.4k citations Allan C. Spradling et al. profile →
Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

1982 1.4k citations Allan C. Spradling et al. Science profile →
Stem cells find their niche

2001 1.1k citations Allan C. Spradling, Daniela Drummond‐Barbosa et al. profile →
The adult Drosophila posterior midgut is maintained by pluripotent stem cells

2005 826 citations Benjamin Ohlstein, Allan C. Spradling profile →
Developmental genetics of oogenesis

1993 765 citations Allan C. Spradling profile →
The BDGP Gene Disruption Project

2004 698 citations Hugo J. Bellen, Yuchun He et al. Genetics profile →
The Berkeley Drosophila Genome Project Gene Disruption Project: Single P-Element Insertions Mutating 25% of Vital Drosophila Genes

1999 661 citations Allan C. Spradling, Todd Laverty et al. Genetics profile →
A Niche Maintaining Germ Line Stem Cells in the Drosophila Ovary

2000 582 citations Ting Xie, Allan C. Spradling Science profile →
A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary

1997 581 citations Allan C. Spradling et al. Development profile →
Mouse Ovarian Germ Cell Cysts Undergo Programmed Breakdown to Form Primordial Follicles

2001 555 citations Allan C. Spradling et al. Developmental Biology profile →
decapentaplegic Is Essential for the Maintenance and Division of Germline Stem Cells in the Drosophila Ovary

1998 538 citations Ting Xie, Allan C. Spradling profile →
Stem Cells and Their Progeny Respond to Nutritional Changes during Drosophila Oogenesis

2001 502 citations Daniela Drummond‐Barbosa, Allan C. Spradling Developmental Biology profile →
Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling

2007 501 citations Benjamin Ohlstein, Allan C. Spradling Science profile →
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes

2011 472 citations Karen L. Schulze, Yuchun He et al. profile →

Peers

Allan C. Spradling

GENET

CMN

Christiane Nüsslein‐Volhard Germany

Michael Levine United States

H. Robert Horvitz United States

Patrick D. Hsu United States

Hugo J. Bellen United States

J. Keith Joung United States

Eric Wieschaus United States

F. Ann Ran United States

Stephen M. Cohen Germany

Ruth Lehmann United States

Christiane Nüsslein‐Volhard Germany

Allan C. Spradling

27.0k ×1.1

6.9k ×1.0

GENET

4.4k ×0.7

CMN

2.6k ×0.5

10.6k ×2.1

Citations per year, relative to Allan C. Spradling Allan C. Spradling (= 1×) peers Christiane Nüsslein‐Volhard

Countries citing papers authored by Allan C. Spradling

Since Specialization

Citations

This map shows the geographic impact of Allan C. Spradling's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Allan C. Spradling with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Allan C. Spradling more than expected).

Fields of papers citing papers by Allan C. Spradling

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Allan C. Spradling. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Allan C. Spradling. The network helps show where Allan C. Spradling may publish in the future.

Co-authorship network of co-authors of Allan C. Spradling

This figure shows the co-authorship network connecting the top 25 collaborators of Allan C. Spradling. A scholar is included among the top collaborators of Allan C. Spradling based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Allan C. Spradling. Allan C. Spradling is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Spradling, Allan C., et al.. (2025). Mouse germline cysts contain a fusome-like structure that mediates oocyte development. eLife. 14.

Spradling, Allan C., et al.. (2025). Early female germline development in Xenopus laevis : Stem cells, nurse cells, and germline cysts. Proceedings of the National Academy of Sciences. 122(46). e2522343122–e2522343122.

Wang, Chenhui & Allan C. Spradling. (2022). Drosophila renal stem cells enhance fitness by delayed remodeling of adult Malpighian tubules. Science Advances. 8(20). eabn7436–eabn7436. 2 indexed citations

Baradaran‐Heravi, Alireza, et al.. (2022). FMRP-dependent production of large dosage-sensitive proteins is highly conserved. Genetics. 221(4). 12 indexed citations

Ikami, Kanako, et al.. (2021). Altered germline cyst formation and oogenesis in Tex14 mutant mice. Biology Open. 10(6). 18 indexed citations

Wang, Chenhui & Allan C. Spradling. (2020). An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones. eLife. 9. 27 indexed citations

Kanca, Oguz, Jonathan Zirin, Jorge García‐Marqués, et al.. (2019). An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. eLife. 8. 94 indexed citations

Greenblatt, Ethan J. & Allan C. Spradling. (2018). Fragile X mental retardation 1 gene enhances the translation of large autism-related proteins. Science. 361(6403). 709–712. 105 indexed citations

DeLuca, Steven Z. & Allan C. Spradling. (2018). Efficient Expression of Genes in the Drosophila Germline Using a UAS Promoter Free of Interference by Hsp70 piRNAs. Genetics. 209(2). 381–387. 54 indexed citations

10.

Lei, Lei & Allan C. Spradling. (2016). Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells. Science. 352(6281). 95–99. 210 indexed citations

11.

Morris, Lucy X. & Allan C. Spradling. (2011). Long-term live imaging provides new insight into stem cell regulation and germline-soma coordination in the Drosophila ovary. Development. 138(11). 2207–2215. 135 indexed citations

12.

Skora, Andrew D. & Allan C. Spradling. (2010). Epigenetic stability increases extensively during Drosophila follicle stem cell differentiation. Proceedings of the National Academy of Sciences. 107(16). 7389–7394. 40 indexed citations

13.

Buszczak, Michael, et al.. (2008). Drosophila Stem Cells Share a Common Requirement for the Histone H2B Ubiquitin Protease Scrawny. Science. 323(5911). 248–251. 98 indexed citations

14.

Ohlstein, Benjamin & Allan C. Spradling. (2007). Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling. Science. 315(5814). 988–992. 501 indexed citations breakdown →

15.

Kai, Toshie & Allan C. Spradling. (2003). An empty Drosophila stem cell niche reactivates the proliferation of ectopic cells. Proceedings of the National Academy of Sciences. 100(8). 4633–4638. 220 indexed citations

16.

Tulin, Alexei V. & Allan C. Spradling. (2003). Chromatin Loosening by Poly(ADP)-Ribose Polymerase (PARP) at Drosophila Puff Loci. Science. 299(5606). 560–562. 368 indexed citations

17.

Tulin, Alexei V., Yurii Chinenov, & Allan C. Spradling. (2003). Regulation of Chromatin Structure and Gene Activity by Poly(ADP-Ribose) Polymerases. Current topics in developmental biology. 56. 55–83. 47 indexed citations

18.

Drummond‐Barbosa, Daniela & Allan C. Spradling. (2003). α-Endosulfine, a potential regulator of insulin secretion, is required for adult tissue growth control in Drosophila. Developmental Biology. 266(2). 310–321. 36 indexed citations

19.

Xie, Ting & Allan C. Spradling. (2000). A Niche Maintaining Germ Line Stem Cells in the Drosophila Ovary. Science. 290(5490). 328–330. 582 indexed citations breakdown →

20.

Misra, Hari S., Daniel A. Beaton, Todd Laverty, et al.. (1999). The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.. Genomics. 40 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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