Alexandre Irrthum

6.0k total citations · 2 hit papers
22 papers, 3.7k citations indexed

About

Alexandre Irrthum is a scholar working on Oncology, Molecular Biology and Cancer Research. According to data from OpenAlex, Alexandre Irrthum has authored 22 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Oncology, 8 papers in Molecular Biology and 7 papers in Cancer Research. Recurrent topics in Alexandre Irrthum's work include Cancer Genomics and Diagnostics (5 papers), Bioinformatics and Genomic Networks (4 papers) and Lymphatic System and Diseases (3 papers). Alexandre Irrthum is often cited by papers focused on Cancer Genomics and Diagnostics (5 papers), Bioinformatics and Genomic Networks (4 papers) and Lymphatic System and Diseases (3 papers). Alexandre Irrthum collaborates with scholars based in Belgium, United States and Netherlands. Alexandre Irrthum's co-authors include Pierre Geurts, Louis Wehenkel, Vân Anh Huynh‐Thu, Miikka Vikkula, Martine Piccart, Charles Swanton, Dimitrios Zardavas, Koenraad Devriendt, Marika J. Karkkainen and Kari Alitalo and has published in prestigious journals such as Nature Genetics, Journal of Clinical Oncology and PLoS ONE.

In The Last Decade

Alexandre Irrthum

22 papers receiving 3.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inferring Regulatory Networks from Expression Data Using Tree-Based Methods

2010 1.3k citations Vân Anh Huynh‐Thu, Alexandre Irrthum et al. PLoS ONE profile →
Clinical management of breast cancer heterogeneity

2015 426 citations Dimitrios Zardavas, Alexandre Irrthum et al. Nature Reviews Clinical Oncology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alexandre Irrthum Belgium	14	2.2k	939	514	475	468	22	3.7k
Afshan McCarthy United Kingdom	31	3.1k 1.4×	1.5k 1.6×	676 1.3×	566 1.2×	378 0.8×	51	4.2k
Wen Shi China	34	3.0k 1.4×	687 0.7×	570 1.1×	472 1.0×	303 0.6×	81	4.5k
Shumpei Ishikawa Japan	37	2.1k 0.9×	1.1k 1.2×	705 1.4×	497 1.0×	553 1.2×	126	4.5k
Akira Tanigami Japan	30	2.0k 0.9×	538 0.6×	427 0.8×	592 1.2×	279 0.6×	71	3.2k
Lisa M. Sapinoso United States	17	3.4k 1.5×	841 0.9×	740 1.4×	419 0.9×	250 0.5×	19	4.8k
Michael Khan United Kingdom	24	2.0k 0.9×	796 0.8×	493 1.0×	331 0.7×	393 0.8×	62	3.4k
Nan Hu China	40	2.8k 1.3×	595 0.6×	825 1.6×	363 0.8×	763 1.6×	199	6.1k
Satrajit Sinha United States	39	3.5k 1.6×	1.9k 2.0×	754 1.5×	619 1.3×	271 0.6×	112	5.3k
L’Houcine Ouafik France	43	2.0k 0.9×	1.4k 1.5×	818 1.6×	252 0.5×	422 0.9×	179	5.0k
Zhongjun Zhou Hong Kong	39	3.4k 1.5×	1.1k 1.2×	1.1k 2.1×	342 0.7×	366 0.8×	121	5.7k

Countries citing papers authored by Alexandre Irrthum

Since Specialization

Citations

This map shows the geographic impact of Alexandre Irrthum's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexandre Irrthum with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexandre Irrthum more than expected).

Fields of papers citing papers by Alexandre Irrthum

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexandre Irrthum. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexandre Irrthum. The network helps show where Alexandre Irrthum may publish in the future.

Co-authorship network of co-authors of Alexandre Irrthum

This figure shows the co-authorship network connecting the top 25 collaborators of Alexandre Irrthum. A scholar is included among the top collaborators of Alexandre Irrthum based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alexandre Irrthum. Alexandre Irrthum is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Caballero, Carmela, Alexandre Irrthum, Theodora Goulioti, et al.. (2023). International research to address the challenges of metastatic breast cancer: the AURORA Program (BIG 14-01). npj Breast Cancer. 9(1). 42–42. 5 indexed citations

Hilbers, Florentine, David Venet, Elisa Agostinetto, et al.. (2023). Characterization of the immune microenvironment in matched primary and metastatic breast cancer lesions from the AURORA study: BIG 14-01.. Journal of Clinical Oncology. 41(16_suppl). 1009–1009. 3 indexed citations

Aftimos, Philippe, Florentine Hilbers, David Venet, et al.. (2019). First report of AURORA, the breast international group (BIG) molecular screening initiative for metastatic breast cancer (MBC) patients (pts). Annals of Oncology. 30. iii48–iii48. 12 indexed citations

Zardavas, Dimitrios, Alexandre Irrthum, Charles Swanton, & Martine Piccart. (2015). Clinical management of breast cancer heterogeneity. Nature Reviews Clinical Oncology. 12(7). 381–394. 426 indexed citations breakdown →

Josse, Claire, Nassim Bouznad, Pierre Geurts, et al.. (2013). Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis. American Journal of Physiology-Gastrointestinal and Liver Physiology. 306(3). G229–G243. 65 indexed citations

Mendola, Antonella, Matthieu J. Schlögel, Arash Ghalamkarpour, et al.. (2013). Mutations in the VEGFR3 Signaling Pathway Explain 36% of Familial Lymphedema. Molecular Syndromology. 4(6). 257–266. 67 indexed citations

Bogie, Jeroen F. J., Vân Anh Huynh‐Thu, Alexandre Irrthum, et al.. (2012). Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation. PLoS ONE. 7(9). e44998–e44998. 65 indexed citations

Garbacki, Nancy, Emmanuel Di Valentin, Vân Anh Huynh‐Thu, et al.. (2011). MicroRNAs Profiling in Murine Models of Acute and Chronic Asthma: A Relationship with mRNAs Targets. PLoS ONE. 6(1). e16509–e16509. 122 indexed citations

Huynh‐Thu, Vân Anh, Alexandre Irrthum, Louis Wehenkel, Yvan Saeys, & Pierre Geurts. (2011). Inferring gene regulatory networks from expression data using tree-based methods. Open Repository and Bibliography (University of Liège). 3 indexed citations

10.

Huynh‐Thu, Vân Anh, Alexandre Irrthum, Louis Wehenkel, Yvan Saeys, & Pierre Geurts. (2010). Regulatory network inference with GENIE3: application to the DREAM5 challenge. Open Repository and Bibliography (University of Liège). 2 indexed citations

11.

Huynh‐Thu, Vân Anh, Alexandre Irrthum, Louis Wehenkel, & Pierre Geurts. (2010). Inferring Regulatory Networks from Expression Data Using Tree-Based Methods. PLoS ONE. 5(9). e12776–e12776. 1257 indexed citations breakdown →

12.

Geurts, Pierre, Alexandre Irrthum, & Louis Wehenkel. (2009). Supervised learning with decision tree-based methods in computational and systems biology. Molecular BioSystems. 5(12). 1593–1605. 164 indexed citations

13.

Wouters, Vinciane, Nisha Limaye, Mélanie Uebelhoer, et al.. (2009). Hereditary cutaneomucosal venous malformations are caused by TIE2 mutations with widely variable hyper-phosphorylating effects. European Journal of Human Genetics. 18(4). 414–420. 111 indexed citations

14.

Irrthum, Alexandre & Louis Wehenkel. (2008). Predicting gene essentiality from expression patterns in Escherichia coli. Open Repository and Bibliography (University of Liège). 1 indexed citations

15.

Tatton‐Brown, Katrina, Jenny Douglas, Kim Coleman, et al.. (2005). Genotype-Phenotype Associations in Sotos Syndrome: An Analysis of 266 Individuals with NSD1 Aberrations. The American Journal of Human Genetics. 77(2). 193–204. 221 indexed citations

16.

Hanks, Sandra, Kim Coleman, Sarah Reid, et al.. (2004). Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nature Genetics. 36(11). 1159–1161. 444 indexed citations

17.

Irrthum, Alexandre, Koenraad Devriendt, David Chitayat, et al.. (2003). Mutations in the Transcription Factor Gene SOX18 Underlie Recessive and Dominant Forms of Hypotrichosis-Lymphedema-Telangiectasia. The American Journal of Human Genetics. 72(6). 1470–1478. 292 indexed citations

18.

Irrthum, Alexandre, et al.. (2001). Linkage disequilibrium narrows locus for venous malformation with glomus cells (VMGLOM) to a single 1.48 Mbp YAC. European Journal of Human Genetics. 9(1). 34–38. 21 indexed citations

19.

Irrthum, Alexandre, Marika J. Karkkainen, Koenraad Devriendt, Kari Alitalo, & Miikka Vikkula. (2000). Congenital Hereditary Lymphedema Caused by a Mutation That Inactivates VEGFR3 Tyrosine Kinase. The American Journal of Human Genetics. 67(2). 295–301. 299 indexed citations

20.

Boon, Laurence M., Pascal Brouillard, Alexandre Irrthum, et al.. (1999). A Gene for Inherited Cutaneous Venous Anomalies (“Glomangiomas”) Localizes to Chromosome 1p21-22. The American Journal of Human Genetics. 65(1). 125–133. 115 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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