Alexander Varshavsky

39.1k citations

226 papers · 31.0k indexed · 14 hit papers · h-index 91

Impact in

Molecular Biology top 0.05%
- Ubiquitin and proteasome pathways
- Fungal and yeast genetics research
- RNA and protein synthesis mechanisms
- Genomics and Chromatin Dynamics
- DNA Repair Mechanisms
Cell Biology top 0.05%
- Endoplasmic Reticulum Stress and Disease

Papers in

Oncology 74
- Peptidase Inhibition and Analysis 61
Molecular Biology 179
- Ubiquitin and proteasome pathways 98
- RNA and protein synthesis mechanisms 33
- Genomics and Chromatin Dynamics 30
- Fungal and yeast genetics research 26
- DNA and Nucleic Acid Chemistry 24
- RNA modifications and cancer 19

Co-authors: Daniel Finley Andreas Bachmair John P. McGrath John W. Tobias Engin Özkaynak Bonnie Bartel Olof Sundin François Strauss
Journals: Proceedings of the National Academy of Sciences (41 papers)Journal of Biological Chemistry (24 papers)Cell (18 papers)Science (12 papers)Nature (9 papers)
Partner nations: United States Russia Germany

In The Last Decade

Alexander Varshavsky

223 papers receiving 29.9k citations

Hit Papers

14 papers align trajectories log scale

N-degron and C-degron pathways of protein degradation 2019 · 390 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Proceedings of the National Academy of Sciences
2011 Protein Science
2010 Science
1995 Journal of Biological Chemistry
1994 Proceedings of the National Academy of Sciences
1989 Nature
1989 Nature
1989 Science
1987 Nature
1987 Cell
1986 Science
1984 Cell
1984 Cell
1984 Cell

Peers

Countries citing papers authored by Alexander Varshavsky

Since Specialization

Citations

This map shows the geographic impact of Alexander Varshavsky's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexander Varshavsky with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexander Varshavsky more than expected).

Fields of papers citing papers by Alexander Varshavsky

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexander Varshavsky. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexander Varshavsky. The network helps show where Alexander Varshavsky may publish in the future.

Co-authors

The 25 scholars most cited alongside Alexander Varshavsky, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alexander Varshavsky Line = papers co-authored together Alexander Varshavsky links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	N-degron pathways Proceedings of the National Academy of Sciences ·Alexander Varshavsky	2024	20
2	Deletions of DNA in cancer and their possible uses for therapy BioEssays ·Alexander Varshavsky, Kim Lewis, Shun‐Jia Chen	2023	2
3	Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates Proceedings of the National Academy of Sciences ·Bong Heon Kim, Min Kyung Kim, Sun Joo Oh, Kha The Nguyen, Jun Hoe Kim, Alexander Varshavsky, Cheol‐Sang Hwang, Hyun Kyu Song	2022	15
4	Aminopeptidases trim Xaa-Pro proteins, initiating their degradation by the Pro/N-degron pathway Proceedings of the National Academy of Sciences ·Shun‐Jia Chen, Leehyeon Kim, Hyun Kyu Song, Alexander Varshavsky	2021	22
5	The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway Biochemistry ·Tri Vu, Alexander Varshavsky	2020	7
6	Evolution of Substrates and Components of the Pro/N-Degron Pathway Biochemistry ·Shun‐Jia Chen, Artem Melnykov, Alexander Varshavsky	2020	8
7	Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway Science ·Jeong‐Mok Kim, Ok-Hee Seok, Shinyeong Ju, Jieun Heo, Jeonghun Yeom, Dasom Kim, Joo‐Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol‐Sang Hwang	2018	72
8	An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes Science ·Shun‐Jia Chen, Xia Wu, Brandon Wadas, Jang‐Hyun Oh, Alexander Varshavsky	2017	157
9	A reference-based protein degradation assay without global translation inhibitors Journal of Biological Chemistry ·Jang‐Hyun Oh, Shun‐Jia Chen, Alexander Varshavsky	2017	14
10	Proceedings of the 14th Workshop on Mobile Computing Systems and Applications Sharad Agarwal, Alexander Varshavsky	2013	9
11	Three Decades of Studies to Understand the Functions of the Ubiquitin Family Methods in molecular biology ·Alexander Varshavsky	2012	12
12	Analysis of two main university rankings Applied Econometrics ·Alexander Varshavsky, Комкина Т.А.	2011	2
13	Location in Ubiquitous Computing Alexander Varshavsky, Shwetak Patel	2010	15
14	Ablation of Arginylation in the Mouse N-End Rule Pathway: Loss of Fat, Higher Metabolic Rate, Damaged Spermatogenesis, and Neurological Perturbations PLoS ONE ·Christopher S. Brower, Alexander Varshavsky	2009	65
15	Targeting the absence: Homozygous DNA deletions as immutable signposts for cancer therapy Proceedings of the National Academy of Sciences ·Alexander Varshavsky	2007	24
16	The N-end rule pathway is a sensor of heme Proceedings of the National Academy of Sciences ·Ronggui Hu, Haiqing Wang, Zanxian Xia, Alexander Varshavsky	2007	100
17	Listeriolysin O Secreted by Listeria monocytogenes into the Host Cell Cytosol Is Degraded by the N-End Rule Pathway Infection and Immunity ·Pamela Schnupf, Jian‐Min Zhou, Alexander Varshavsky, Daniel A. Portnoy	2007	44
18	Ubiquitin fusion technique and its descendants Methods in enzymology on CD-ROM/Methods in enzymology ·Alexander Varshavsky	2000	54
19	An Essential Yeast Gene Encoding a Homolog of Ubiquitin-activating Enzyme Journal of Biological Chemistry ·R. Jürgen Dohmen, Reiner Stappen, John P. McGrath, Helena Forrová, Jordan Kolarov, André Goffeau, Alexander Varshavsky	1995	171
20	The N-end rule Cell ·Alexander Varshavsky	1992	421

About Alexander Varshavsky

Alexander Varshavsky is a scholar working on Oncology, Molecular Biology, Cell Biology, Transportation and Development, having authored 226 papers that have together received 31.0k indexed citations. Recurring topics across this work include Ubiquitin and proteasome pathways (98 papers), Peptidase Inhibition and Analysis (61 papers), RNA and protein synthesis mechanisms (33 papers), Genomics and Chromatin Dynamics (30 papers), Fungal and yeast genetics research (26 papers), DNA and Nucleic Acid Chemistry (24 papers), RNA modifications and cancer (19 papers) and Endoplasmic Reticulum Stress and Disease (16 papers). The work is most often cited by research in Molecular Biology (25.5k citations), Cell Biology (5.2k citations), Oncology (7.5k citations), Aging (299 citations) and Transportation (755 citations). Alexander Varshavsky has collaborated with scholars based in United States, Russia and Germany. Frequent co-authors include Daniel Finley, Andreas Bachmair, John P. McGrath, John W. Tobias, Engin Özkaynak, Bonnie Bartel, Olof Sundin, François Strauss, Nils Johnsson and Michael J. Solomon. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Cell, Science and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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