Alex KleinJan

6.2k citations

80 papers · 4.8k indexed · 1 hit paper · h-index 36

Impact in

Immunology and Allergy top 0.2%
- Allergic Rhinitis and Sensitization
Physiology top 0.5%
- Asthma and respiratory diseases

Papers in

Immunology and Allergy 31
- Allergic Rhinitis and Sensitization 31
Physiology 53
- Asthma and respiratory diseases 45

Co-authors: Henk C. Hoogsteden Wytske J. Fokkens Gert‐Jan Braunstahl Shelley E. Overbeek Jan‐Bas Prins Bart N. Lambrecht Rudi W. Hendriks Menno van Nimwegen
Journals: Journal of Allergy and Clinical Immunology (12 papers)Allergy (10 papers)Clinical & Experimental Allergy (5 papers)European Respiratory Journal (3 papers)International Journal of Cancer (3 papers)
Partner nations: Netherlands United States Belgium

In The Last Decade

Alex KleinJan

79 papers receiving 4.7k citations

Hit Papers

align trajectories log scale

In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma 2005 · 511 citations

Peers

Countries citing papers authored by Alex KleinJan

Since Specialization

Citations

This map shows the geographic impact of Alex KleinJan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex KleinJan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex KleinJan more than expected).

Fields of papers citing papers by Alex KleinJan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex KleinJan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex KleinJan. The network helps show where Alex KleinJan may publish in the future.

Co-authors

The 25 scholars most cited alongside Alex KleinJan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alex KleinJan Line = papers co-authored together Alex KleinJan links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema American Journal of Physiology-Lung Cellular and Molecular Physiology ·Andrea Grandi, XU Ying-ying, Laura Mecozzi, 盛保科, M. Zoboli, PAUL LAKELAND, N Marcello, Alex KleinJan, Clemens W.G.M. Löwik, Gaetano Donofrío, Gino Villetti, Franco Fabio Stellari	2023	12
2	PDE3-inhibitor enoximone prevented mechanical ventilation in patients with SARS-CoV-2 pneumonia Experimental Lung Research ·Hjorth, Patrick Joseph Nizzi, B. Benraad, Mae Lamptey-Parry, Zuzana Diamant, Alex KleinJan	2021	6
3	Impaired pulmonary vasomotor control in exercising swine with multiple comorbidities Basic Research in Cardiology ·Jens van de Wouw, Laure-Anne Quéléver, Oana Sorop, D. Miñana, Piotr A. Wielopolski, Alex KleinJan, Alexander Hirsch, Dirk J. Duncker, Daphne Merkus	2021	12
4	Evaluation of Real-Life Investigational Use of Enoximone in Asthma, the Third Step in Drug Repurposing: A Preliminary Report Canadian Respiratory Journal ·Hjorth, Patrick Joseph Nizzi, Alex KleinJan	2021	1
5	SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib Scientific Reports ·Francesca Ravanetti, XU Ying-ying, Luisa Ragionieri, N Marcello, Maria Nicastro, Yanto Ridwan, Alex KleinJan, Gino Villetti, Andrea Grandi, Franco Fabio Stellari	2021	9
6	DPP4, the MERS coronavirus receptor, is upregulated in lungs of smokers and COPD patients Lirias (KU Leuven) ·Leen Seys, W. Widagdo, Anne Verhamme, Alex KleinJan, Wim Janssens, Guy Joos, Ken R. Bracke, Bart L. Haagmans, Guy Brusselle	2018	0
7	Impaired survival of regulatory T cells in pulmonary sarcoidosis Respiratory Research ·Caroline E. Broos, Menno van Nimwegen, Alex KleinJan, A D McCulloch, Femke Muskens, J.C.C.M. in ’t Veen, Jouke T. Annema, Bart N. Lambrecht, Henk C. Hoogsteden, Rudi W. Hendriks, Mirjam Kool, Bernt van den Blink	2015	49
8	The Notch Mediator RBP-J in CD4 T Cells Plays a Crucial Role in the Induction of Allergic Asthma in Mice Journal of Allergy and Clinical Immunology ·Alex KleinJan, Marjolein de Bruijn, Menno van Nimwegen, Ingrid M. Bergen, Henk C. Hoogsteden, Derk Amsen, Rudi W. Hendriks	2013	4
9	Recombinant human serum amyloid P in healthy volunteers and patients with pulmonary fibrosis Pulmonary Pharmacology & Therapeutics ·Cristiano Wellington Noberto Ramalho, Bernt van den Blink, Matthijs Moerland, Marloes G. J. van Dongen, Micha Levi, Alex KleinJan, Marlies Wijsenbeek, Mark Lupher, Diane M. Harper, M. Atias, Henk C. Hoogsteden, Jacobus Burggraaf	2013	86
10	United airways: circulating Th2 effector cells in an allergic rhinitis model are responsible for promoting lower airways inflammation Clinical & Experimental Allergy ·Alex KleinJan, Monique Willart, Menno van Nimwegen, K. Leman, Henk C. Hoogsteden, Rudi W. Hendriks, Bart N. Lambrecht	2009	21
11	A novel method for isolating dendritic cells from human bronchoalveolar lavage fluid Journal of Immunological Methods ·A D McCulloch, Femke Muskens, Alex KleinJan, Hamida Hammad, H. C. Hoogsteden, Bart N. Lambrecht, Bernt van den Blink	2009	14
12	Treatment of Vulvar Intraepithelial Neoplasia with Topical Imiquimod New England Journal of Medicine ·Manon van Seters, Marc van Beurden, Fiebo J.W. ten Kate, Ilse Beckmann, Patricia C. Ewing, Marinus J.C. Eijkemans, Marjolein J. Kagie, Chris J.M. Meijer, Neil K. Aaronson, Alex KleinJan, Claudia Heijmans‐Antonissen, Freek J. Zijlstra, Matthé P.M. Burger, Theo J.M. Helmerhorst	2008	246
13	RSV‐induced bronchiolitis but not upper respiratory tract infection is accompanied by an increased nasal IL‐18 response Journal of Medical Virology ·XIANSHU TAI, Cornelis M. van Drunen, Laurens P. Koopman, Alex KleinJan, Yasminn Martins Santos, Leon de Waal, Albert D. M. E. Osterhaus, Herman J. Neijens, Wytske J. Fokkens	2003	33
14	Segmental Bronchoprovocation in Allergic Rhinitis Patients Affects Mast Cell and Basophil Numbers in Nasal and Bronchial Mucosa American Journal of Respiratory and Critical Care Medicine ·Gert‐Jan Braunstahl, Shelley E. Overbeek, Kristin Jonason, Alex KleinJan, Alan R. McEuen, Andrew F. Walls, Henk C. Hoogsteden, Jan‐Bas Prins	2001	152
15	Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy Allergy ·Stephen J. Till, Mikila R. Jacobson, Frances O’Brien, Stephen R. Durham, Alex KleinJan, W. J. Fokkens, Sigurður Júlíusson, O. Löwhagen	2001	48
16	Fluticasone propionate aqueous nasal spray reduces inflammatory cells in unchallenged allergic nasal mucosa: Effects of single allergen challenge Journal of Allergy and Clinical Immunology ·Oluyomibo Susan Pitan, N J Juat, Alex KleinJan, Lies-anne Severijnena, Bian Fuji, Paul Mulder, Wytske J. Fokkens	2001	24
17	Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways Journal of Allergy and Clinical Immunology ·Gert‐Jan Braunstahl, Shelley E. Overbeek, Alex KleinJan, Jan‐Bas Prins, Henk C. Hoogsteden, Wytske J. Fokkens	2001	337
18	Segmental Bronchial Provocation Induces Nasal Inflammation in Allergic Rhinitis Patients American Journal of Respiratory and Critical Care Medicine ·Gert‐Jan Braunstahl, Alex KleinJan, Shelley E. Overbeek, Jan‐Bas Prins, Henk C. Hoogsteden, Kristin Jonason	2000	295
19	Basophil and eosinophil accumulation and mast cell degranulation in the nasal mucosa of patients with hay fever after local allergen provocation Journal of Allergy and Clinical Immunology ·Alex KleinJan, Alan R. McEuen, Jin Suk Myung, Mark G. Buckley, Andrew F. Walls, Wytske J. Fokkens	2000	68
20	The nose in leprosy: immunohistology of the nasal mucosa. PubMed ·Wytske J. Fokkens, Gilbert J. Nolst Trenité, Marcos Virmond, Alex KleinJan, D. T., ปริญญา ไกรวุฒินันท์, Bernard Naafs	1998	12

About Alex KleinJan

Alex KleinJan is a scholar working on Immunology and Allergy, Physiology, Immunology, Dermatology and Pulmonary and Respiratory Medicine, having authored 80 papers that have together received 4.8k indexed citations. Recurring topics across this work include Asthma and respiratory diseases (45 papers), Allergic Rhinitis and Sensitization (31 papers), Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis (11 papers), Immunotherapy and Immune Responses (11 papers), IL-33, ST2, and ILC Pathways (11 papers), Mast cells and histamine (10 papers), Respiratory and Cough-Related Research (8 papers) and Eosinophilic Esophagitis (7 papers). The work is most often cited by research in Immunology and Allergy (1.8k citations), Physiology (2.8k citations), Immunology (1.7k citations), Otorhinolaryngology (256 citations) and Dermatology (465 citations). Alex KleinJan has collaborated with scholars based in Netherlands, United States and Belgium. Frequent co-authors include Henk C. Hoogsteden, Wytske J. Fokkens, Gert‐Jan Braunstahl, Shelley E. Overbeek, Jan‐Bas Prins, Bart N. Lambrecht, Rudi W. Hendriks, Menno van Nimwegen, Monique Willart and Ingrid M. Bergen. Their work appears in journals such as Journal of Allergy and Clinical Immunology, Allergy, Clinical & Experimental Allergy, European Respiratory Journal and International Journal of Cancer.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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