Aleem Syed

1.6k total citations · 1 hit paper
27 papers, 1.2k citations indexed

About

Aleem Syed is a scholar working on Molecular Biology, Oncology and Materials Chemistry. According to data from OpenAlex, Aleem Syed has authored 27 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 7 papers in Oncology and 6 papers in Materials Chemistry. Recurrent topics in Aleem Syed's work include DNA Repair Mechanisms (10 papers), PARP inhibition in cancer therapy (5 papers) and CRISPR and Genetic Engineering (4 papers). Aleem Syed is often cited by papers focused on DNA Repair Mechanisms (10 papers), PARP inhibition in cancer therapy (5 papers) and CRISPR and Genetic Engineering (4 papers). Aleem Syed collaborates with scholars based in United States, Canada and United Kingdom. Aleem Syed's co-authors include John A. Tainer, Emily A. Smith, Arthur H. Winter, Toshia Albright, Christie L. Beck, Julie Peterson, Andrew S. Dutton, Elizabeth J. Gehrmann, Chamari S. Wijesooriya and Alan D. D’Andrea and has published in prestigious journals such as Nature, Journal of the American Chemical Society and Nucleic Acids Research.

In The Last Decade

Aleem Syed

27 papers receiving 1.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors

2021 226 citations Jia Zhou, Camille Gelot et al. Nature Cancer profile →

Peers

Countries citing papers authored by Aleem Syed

Since Specialization

Citations

This map shows the geographic impact of Aleem Syed's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Aleem Syed with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Aleem Syed more than expected).

Fields of papers citing papers by Aleem Syed

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Aleem Syed. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Aleem Syed. The network helps show where Aleem Syed may publish in the future.

Co-authorship network of co-authors of Aleem Syed

This figure shows the co-authorship network connecting the top 25 collaborators of Aleem Syed. A scholar is included among the top collaborators of Aleem Syed based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Aleem Syed. Aleem Syed is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Non-enzymatic protein targeting agents as a promising strategy for cancer treatment 2025 ·SHILAP Revista de lepidopterología ·(unknown), Jin‐Hyung Lee, Aleem Syed, Zamal Ahmed, Guang Peng	1
2	CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair 2025 ·Nature Communications ·Feng Li, Tianpeng Zhang, Aleem Syed, (unknown), (unknown), Huy Nguyen, (unknown), Roger A. Greenberg, Alan D. D’Andrea	2
3	Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation 2024 ·Journal of Biological Chemistry ·(unknown), Albino Bacolla, Aleem Syed, John A. Tainer	2
4	ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase 2024 ·Journal of Biological Chemistry ·Naga Babu Chinnam, Roopa Thapar, (unknown), Altaf H. Sarker, Jennifer M. Soll, (unknown), Aleem Syed, Daniel J. Rosenberg, Michal Hammel, Albino Bacolla, Panagiotis Katsonis, Abhishek Asthana, Miaw-Sheue Tsai, Ivaylo Ivanov, Olivier Lichtarge, Robert H. Silverman, Nima Mosammaparast, Susan E. Tsutakawa, John A. Tainer	4
5	CDK5–cyclin B1 regulates mitotic fidelity 2024 ·Nature ·Xiao-Feng Zheng, (unknown), (unknown), Aleem Syed, Huy Nguyen, Richard G. Ivey, Jacob J. Kennedy, Jeffrey R. Whiteaker, Bartłomiej Tomasik, Kaimeng Huang, Feng Li, Alan D. D’Andrea, Amanda G. Paulovich, Kavita Shah, Alexander Spektor, Dipanjan Chowdhury	4
6	NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity 2024 ·Nature Communications ·(unknown), Aleem Syed, Patrick Toolan-Kerr, (unknown), Shrabasti Roychoudhury, (unknown), Sarah E. Wilkins, Mikayla Quigley, Anna R. Poetsch, Maria Victoria Botuyan, Gaofeng Cui, Georges Mer, Jernej Ule, Pascal Drané, Dipanjan Chowdhury	4
7	Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology 2024 ·Nature Communications ·(unknown), Vladimir Sarpe, (unknown), (unknown), Morgan F. Khan, Pauline Douglas, Stephen J. Coales, Rosa Viner, Aleem Syed, John A. Tainer, Susan P. Lees‐Miller, David C. Schriemer	15
8	Dynamics of the DYNLL1–MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs 2023 ·Nature Structural & Molecular Biology ·(unknown), Rui Zhou, Aleem Syed, Lisa A. Moreau, Bartłomiej Tomasik, John A. Tainer, Panagiotis A. Konstantinopoulos, Alan D. D’Andrea, Yizhou He, Dipanjan Chowdhury	19
9	Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity 2023 ·Nucleic Acids Research ·Aleem Syed, (unknown), Jeffrey Patterson-Fortin, Albino Bacolla, (unknown), Jia Zhou, (unknown), (unknown), (unknown), J.A. Newman, Miaw-Sheue Tsai, Darin E. Jones, David C. Schriemer, (unknown), John A. Tainer	22
10	Monitoring Nuclease Activity by X-Ray Scattering Interferometry Using Gold Nanoparticle-Conjugated DNA 2022 ·Methods in molecular biology ·Daniel J. Rosenberg, Aleem Syed, John A. Tainer, Greg L. Hura	5
11	Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution 2022 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Naga Babu Chinnam, Aleem Syed, Greg L. Hura, Michal Hammel, John A. Tainer, Susan E. Tsutakawa	11
12	Universally Accessible Structural Data on Macromolecular Conformation, Assembly, and Dynamics by Small Angle X-Ray Scattering for DNA Repair Insights 2022 ·Methods in molecular biology ·Naga Babu Chinnam, Aleem Syed, (unknown), Greg L. Hura, John A. Tainer, Susan E. Tsutakawa	1
13	A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors breakdown → 2021 ·Nature Cancer ·Jia Zhou, Camille Gelot, Constantia Pantelidou, Adam Y. Li, Hatice Yücel, Rachel E. Davis, Anniina Färkkilä, Bose Kochupurakkal, Aleem Syed, Geoffrey I. Shapiro, John A. Tainer, Brian S. J. Blagg, Raphaël Ceccaldi, Alan D. D’Andrea	226
14	Charge Transport Communication through DNA by Protein Fe–S Clusters: How Far Is Not Too Far? 2019 ·ACS Central Science ·Aleem Syed, John A. Tainer	6
15	Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities 2018 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Davide Moiani, Daryl A. Ronato, Chris A. Brosey, A.S. Arvai, Aleem Syed, Jean‐Yves Masson, Elena Petricci, John A. Tainer	21
16	Lateral diffusion and signaling of receptor for advanced glycation end-products (RAGE): a receptor involved in chronic inflammation 2017 ·European Biophysics Journal ·Aleem Syed, Qiaochu Zhu, Emily A. Smith	4
17	The role of a conserved membrane proximal cysteine in alteringαPS2CβPS integrin diffusion 2016 ·Physical Biology ·Aleem Syed, Neha Arora, Thomas A. Bunch, Emily A. Smith	1
18	Ligand binding affinity and changes in the lateral diffusion of receptor for advanced glycation endproducts (RAGE) 2016 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Aleem Syed, Qiaochu Zhu, Emily A. Smith	9
19	Single particle tracking with sterol modulation reveals the cholesterol-mediated diffusion properties of integrin receptors 2014 ·Physical Biology ·(unknown), Aleem Syed, Suzanne Sander, Emily A. Smith	9
20	Role of insulin receptor and insulin signaling on αPS2CβPS integrins’ lateral diffusion 2014 ·European Biophysics Journal ·(unknown), Aleem Syed, (unknown), Emily A. Smith	3

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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