Standout Papers

Mutant presenilins specifically elevate the levels of the 42 residue ... 1995 2026 2005 2015 1.2k
  1. Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase (2003)
    Joanna L. Jankowsky, Jeffrey C. Anderson et al. Human Molecular Genetics
  2. Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo (1996)
    David Borchelt, Gopal Thinakaran et al. Neuron
  3. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria (1995)
    Philip C. Wong, Carlos A. Pardo et al. Neuron
  4. ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions (1997)
    Lucie Bruijn, Mark W. Bêcher et al. Neuron
  5. Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo (1996)
    Gopal Thinakaran, David Borchelt et al. Neuron
  6. Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis (2010)
    Venu M. Nemani, Wei Lü et al. Neuron
  7. Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins (1997)
    David Borchelt, Tamara Ratovitski et al. Neuron
  8. Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice (2002)
    Michael K. Lee, Wanda L.H. Stirling et al. Proceedings of the National Academy of Sciences
  9. Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis (1996)
    Martina Wiedau‐Pazos, Jun Goto et al. Science
  10. The expression and posttranslational modification of a neuron‐specific β‐tubulin isotype during chick embryogenesis (1990)
    Michael K. Lee, Jeremy B. Tuttle et al. Cell Motility and the Cytoskeleton
  11. Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death (2006)
    Lee J. Martin, Yan Pan et al. Journal of Neuroscience

Immediate Impact

9 by Nobel laureates 78 from Science/Nature 149 standout
Sub-graph 1 of 13

Citing Papers

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease
2022 StandoutScience
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
2020 StandoutNature
3 intermediate papers

Works of Michael K. Lee being referenced

Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification
2017
Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
2010 Standout
and 3 more

Author Peers

Author Last Decade Papers Cites
Michael K. Lee 7880 7872 5549 7503 150 19.7k
Philip C. Wong 7062 5178 3096 7061 146 16.3k
David Borchelt 12056 7461 6652 12609 222 26.8k
Leonard Petrucelli 11031 12708 4594 7032 231 22.7k
Robert J. Ferrante 14179 9639 12883 3706 160 25.8k
Masato Hasegawa 10560 16023 6551 13788 309 27.4k
Lee J. Martin 8950 5270 8676 4249 240 21.4k
Jada Lewis 4956 3238 3825 7795 95 12.3k
Vernice Jackson‐Lewis 5844 8454 7419 3421 89 17.5k
Edward Rockenstein 7785 9849 8618 10342 199 24.3k
Tamás Révész 5388 14075 5771 7345 245 21.2k

All Works

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