Standout Papers

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B 1997 2026 2006 2016 1.0k
  1. Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B (1997)
    David Stokoe, Len Stephens et al. Science
  2. Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine (2000)
    Edward H. Walker, Michael E. Pacold et al. Molecular Cell
  3. Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B (1998)
    Len Stephens, Karen E. Anderson et al. Science
  4. PI3K signalling: the path to discovery and understanding (2012)
    Bart Vanhaesebroeck, Len Stephens et al. Nature Reviews Molecular Cell Biology
  5. Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ (2000)
    Michael E. Pacold, Sabine Suire et al. Cell
  6. A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits (1994)
    Len Stephens, Alan V. Smrcka et al. Cell
  7. PI3K signalling in inflammation (2014)
    Phillip T. Hawkins, Len Stephens Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Immediate Impact

11 by Nobel laureates 69 from Science/Nature 156 standout
Sub-graph 1 of 11

Citing Papers

Harnessing innate immunity in cancer therapy
2019 StandoutNature
RAS Proteins and Their Regulators in Human Disease
2017 Standout
47 intermediate papers

Works of Len Stephens being referenced

Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils
2006
Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ
2000 Standout
and 24 more

Author Peers

Author Last Decade Papers Cites
Len Stephens 13204 4636 3843 174 18.9k
Phillip T. Hawkins 12704 4444 3699 177 18.5k
Alex Toker 14885 3648 2244 135 20.2k
Zhou Songyang 14975 2806 3024 189 19.6k
Matthias P. Wymann 8949 1662 3855 137 14.5k
Jonathan Backer 12475 4771 1690 146 17.3k
Bart Vanhaesebroeck 14367 2561 5674 192 22.2k
Rony Seger 14788 3016 2487 204 22.0k
Alan L. Schwartz 9133 3443 1648 176 14.2k
Koiti Titani 10883 2560 2357 291 19.0k
Naoki Mochizuki 10303 4419 1507 248 16.7k

All Works

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2026