Standout Papers

Targeting the dynamic HSP90 complex in c... 1989 2026 2001 2013 1.2k
  1. Targeting the dynamic HSP90 complex in cancer (2010)
    Jane B. Trepel, Mehdi Mollapour et al. Nature reviews. Cancer
  2. Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation. (1994)
    Luke Whitesell, Edward G. Mimnaugh et al. Proceedings of the National Academy of Sciences
  3. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability (2005)
    Jennifer S. Isaacs, Yun Jin Jung et al. Cancer Cell
  4. Characterization of oligonucleotide transport into living cells. (1989)
    S.L. Loke, C.A. Stein et al. Proceedings of the National Academy of Sciences
  5. IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis (2003)
    Yunjin Jung, Jennifer S. Isaacs et al. The FASEB Journal
  6. Hsp90 inhibitors as novel cancer chemotherapeutic agents (2002)
    Len Neckers Trends in Molecular Medicine

Immediate Impact

32 by Nobel laureates 31 from Science/Nature 108 standout
Sub-graph 1 of 18

Citing Papers

Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity
2019 StandoutNature
In vivo aspects of protein folding and quality control
2016 StandoutScience
21 intermediate papers

Works of Len Neckers being referenced

The Therapeutic Target Hsp90 and Cancer Hallmarks
2012
Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex
2005
and 32 more

Author Peers

Author Last Decade Papers Cites
Len Neckers 19155 3924 3039 245 24.6k
Jane B. Trepel 11620 2204 4354 288 17.3k
Carmen Garrido 13089 3878 2696 267 19.9k
Laurence H. Pearl 17768 2087 2403 214 21.0k
Luke Whitesell 10104 4101 1676 144 15.4k
Marja Jäättelä 15004 3006 2431 180 23.4k
William B. Pratt 15895 3355 1567 203 20.7k
Stuart K. Calderwood 12160 3334 1446 230 16.1k
Matthias Gaestel 11385 3271 2296 258 16.3k
Lorenzo A. Pinna 15777 1407 3341 447 21.3k
Alexander Levitzki 14219 2186 5812 328 22.2k

All Works

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2026