Standout Papers

Human acute myeloid leukemia is organized as a hierarchy that originates from a primi... 1994 2026 2004 2015 5.0k
  1. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell (1997)
    Dominique Bonnet, John E. Dick Nature Medicine
  2. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice (1994)
    Tsvee Lapidot, Christian Sirard et al. Nature
  3. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice (2006)
    Catherine O′Brien, Aaron Pollett et al. Nature
  4. Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells (2006)
    Michael F. Clarke, John E. Dick et al. Cancer Research
  5. Evolution of the Cancer Stem Cell Model (2014)
    Antonija Kreso, John E. Dick Cell stem cell
  6. Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry (2009)
    Dmitry Bandura, Vladimir Baranov et al. Analytical Chemistry
  7. Targeting of CD44 eradicates human acute myeloid leukemic stem cells (2006)
    Liqing Jin, Kristin J. Hope et al. Nature Medicine
  8. Stem cell concepts renew cancer research (2008)
    John E. Dick Blood
  9. Stem cell gene expression programs influence clinical outcome in human leukemia (2011)
    Kolja Eppert, Katsuto Takenaka et al. Nature Medicine
  10. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity (2004)
    Kristin J. Hope, Liqing Jin et al. Nature Immunology
  11. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice (1997)
    Mickie Bhatia, Jean Wang et al. Proceedings of the National Academy of Sciences
  12. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy (1996)
    André Larochelle, Josef Vormoor et al. Nature Medicine
  13. Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment (2011)
    Faiyaz Notta, Sergei Doulatov et al. Science
  14. Hematopoiesis: A Human Perspective (2012)
    Sergei Doulatov, Faiyaz Notta et al. Cell stem cell
  15. Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer (2012)
    Antonija Kreso, Catherine O′Brien et al. Science
  16. Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice (1985)
    John E. Dick, Maria Cristina Magli et al. Cell
  17. Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia (2012)
    Tino Schenk, Weihsu Claire Chen et al. Nature Medicine
  18. Distinct routes of lineage development reshape the human blood hierarchy across ontogeny (2015)
    Faiyaz Notta, Sasan Zandi et al. Science
  19. Quantitative single-cell proteomics as a tool to characterize cellular hierarchies (2021)
    Erwin M. Schoof, Benjamin Furtwängler et al. Nature Communications
  20. A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia (2022)
    Andy G.X. Zeng, Liqing Jin et al. Nature Medicine

Immediate Impact

4 by Nobel laureates 115 from Science/Nature 280 standout
Sub-graph 1 of 13

Citing Papers

A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
2017 StandoutNature
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
27 intermediate papers

Works of John E. Dick being referenced

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells
2007
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
2006 Standout
and 21 more

Author Peers

Author Last Decade Papers Cites
John E. Dick 11792 20807 8335 17047 260 39.9k
Connie J. Eaves 11428 13915 5938 8787 393 28.8k
Owen N. Witte 10650 14642 9441 7240 350 35.5k
Malcolm A.S. Moore 6940 13031 7298 7483 336 28.2k
A. Thomas Look 8713 20808 6982 8166 383 39.9k
Daniel Birnbaum 3904 17111 3991 12576 550 31.2k
David A. Cheresh 3700 28065 6447 10157 241 48.0k
Charles L. Sawyers 15494 24460 3180 12045 263 52.5k
Daniel G. Tenen 10137 20026 8658 7218 364 33.2k
Scott W. Lowe 3317 49438 8330 22670 324 68.3k
Joan S. Brugge 3131 25405 5146 10106 258 41.4k

All Works

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2026