Standout Papers

Identification of stem cells in small intestine and colon by marker gene Lgr5... 2003 2026 2010 2018 4.2k
  1. Identification of stem cells in small intestine and colon by marker gene Lgr5 (2007)
    Nick Barker, Johan H. van Es et al. Nature
  2. Crypt stem cells as the cells-of-origin of intestinal cancer (2008)
    Nick Barker, Rachel A. Ridgway et al. Nature
  3. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells (2005)
    Johan H. van Es, Mariëlle van Gijn et al. Nature
  4. Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro (2010)
    Nick Barker, Meritxell Huch et al. Cell stem cell
  5. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium (2003)
    Daniel Pinto, Alex Gregorieff et al. Genes & Development
  6. Sequential cancer mutations in cultured human intestinal stem cells (2015)
    Jarno Drost, Richard H. van Jaarsveld et al. Nature
  7. In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection (2014)
    Sina Bartfeld, Marc van de Wetering et al. Gastroenterology
  8. De Novo Crypt Formation and Juvenile Polyposis on BMP Inhibition in Mouse Intestine (2004)
    Anna-Pavlina G. Haramis, Harry Begthel et al. Science
  9. Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin (2010)
    Hugo J.G. Snippert, Andrea Haegebarth et al. Science
  10. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids (2018)
    Huili Hu, Helmuth Gehart et al. Cell
  11. Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate (2009)
    Laurens G. van der Flier, Mariëlle van Gijn et al. Cell
  12. Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures (2014)
    Wouter R. Karthaus, Phillip J. Iaquinta et al. Cell
  13. Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis (2013)
    Meritxell Huch, Paola Bonfanti et al. The EMBO Journal
  14. Wnt signalling induces maturation of Paneth cells in intestinal crypts (2005)
    Johan H. van Es, Philippe Jay et al. Nature Cell Biology
  15. Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters (2016)
    Paul W. Tetteh, Onur Başak et al. Cell stem cell
  16. Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution (2021)
    Georg Busslinger, Bas L. Weusten et al. Cell Reports

Immediate Impact

15 by Nobel laureates 147 from Science/Nature 290 standout
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Citing Papers

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell
2019 StandoutNature
Self-organization and symmetry breaking in intestinal organoid development
2019 StandoutNature
105 intermediate papers

Works of Harry Begthel being referenced

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters
2016 Standout
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
2005 StandoutNature
and 18 more

Author Peers

Author Last Decade Papers Cites
Harry Begthel 10333 8590 3697 58 18.4k
Daniel E. Stange 9361 9170 3863 63 18.4k
Maaike van den Born 12049 9276 4380 34 20.3k
Hugo J.G. Snippert 8482 7480 2787 53 16.4k
Pekka Kujala 7881 6910 3072 44 15.7k
Jeroen Korving 6936 4945 2315 53 11.9k
Eduard Batlle 11521 9198 1859 85 19.4k
Marc van de Wetering 20452 12738 6079 83 32.3k
Arie Abo 8605 4224 1913 56 14.9k
Bon‐Kyoung Koo 6397 3726 1904 98 11.3k
Linheng Li 8130 3715 1778 129 15.6k

All Works

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2026