Standout Papers

Inflammasome-mediated dysbiosis regulates progression... 2001 2026 2009 2017 1.9k
  1. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity (2012)
    Jorge Henao‐Mejia, Eran Elinav et al. Nature
  2. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome (2001)
    Hal M. Hoffman, James L. Mueller et al. Nature Genetics
  3. NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria (2016)
    Zhenyu Zhong, Atsushi Umemura et al. Cell
  4. NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice (2013)
    Alexander Wree, Akiko Eguchi et al. Hepatology
  5. Glyburide inhibits the Cryopyrin/Nalp3 inflammasome (2009)
    Mohamed Lamkanfi, James L. Mueller et al. The Journal of Cell Biology
  6. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity (2005)
    George Y. Liu, Anthony Essex et al. The Journal of Experimental Medicine
  7. From NAFLD to NASH to cirrhosis—new insights into disease mechanisms (2013)
    Alexander Wree, Lori Broderick et al. Nature Reviews Gastroenterology & Hepatology
  8. Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling (2022)
    Hongxu Xian, Kosuke Watari et al. Immunity
  9. NLRP3 inflammasome activation is required for fibrosis development in NAFLD (2014)
    Alexander Wree, Matthew D. McGeough et al. Journal of Molecular Medicine
  10. Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis (2020)
    Susanne Gaul, Aleksandra Leszczynska et al. Journal of Hepatology

Immediate Impact

1 by Nobel laureates 58 from Science/Nature 221 standout
Sub-graph 1 of 14

Citing Papers

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases
2024 StandoutNature
Lysosomes drive the piecemeal removal of mitochondrial inner membrane
2024 StandoutNature
9 intermediate papers

Works of Hal M. Hoffman being referenced

Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling
2022 Standout
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
2016 Standout
and 1 more

Author Peers

Author Last Decade Papers Cites
Hal M. Hoffman 11595 6346 2141 3985 150 17.3k
Kate Schroder 14096 9654 1963 3572 140 23.1k
Naofumi Mukaida 7275 12463 2550 3394 376 28.1k
Fabio Martinon 18250 12821 2822 3507 96 27.4k
Mohamed Lamkanfi 16445 10094 2154 3059 107 22.1k
Jenny P.‐Y. Ting 14824 13225 2082 3566 213 25.1k
Giamila Fantuzzi 6900 6456 1899 5494 196 19.2k
Haruki Okamura 8356 10878 1345 2497 238 18.4k
Fayyaz S. Sutterwala 8708 7261 1288 2563 117 15.3k
Manolis Pasparakis 13098 12179 1495 3205 193 26.1k
Roy L. Silverstein 11599 7676 3291 2997 207 23.6k

All Works

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2026