Standout Papers

Notch/γ-secretase inhibition turns proliferative cells in intestinal cryp... 1999 2026 2008 2017 1.2k
  1. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells (2005)
    Johan H. van Es, Mariëlle van Gijn et al. Nature
  2. Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1 (1999)
    Freddy Radtke, Anne E. Wilson et al. Immunity
  3. Notch1 functions as a tumor suppressor in mouse skin (2003)
    Michaël Nicolas, Anita Wolfer et al. Nature Genetics
  4. VEGF is required for growth and survival in neonatal mice (1999)
    Hans‐Peter Gerber, Kenneth J. Hillan et al. Development
  5. The role of Notch in tumorigenesis: oncogene or tumour suppressor? (2003)
    Freddy Radtke, Kenneth Raj Nature reviews. Cancer
  6. Self-Renewal and Cancer of the Gut: Two Sides of a Coin (2005)
    Freddy Radtke, Hans Clevers Science
  7. Signalling strength determines proapoptotic functions of STING (2017)
    Muhammet F. Gülen, Ute Koch et al. Nature Communications
  8. Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27 Kip1 and p57 Kip2 (2008)
    Orbicia Riccio, Mariëlle van Gijn et al. EMBO Reports
  9. Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo (2024)
    L. Francisco Lorenzo‐Martín, Tania Hübscher et al. Nature

Immediate Impact

6 by Nobel laureates 53 from Science/Nature 115 standout
Sub-graph 1 of 17

Citing Papers

Biological functions of lymphatic vessels
2020 StandoutScience
Metabolic heterogeneity confers differences in melanoma metastatic potential
2019 StandoutNature

Works of Freddy Radtke being referenced

AMPK promotes survival of c‐Myc‐positive melanoma cells by suppressing oxidative stress
2018
DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport
2015

Author Peers

Author Last Decade Papers Cites
Freddy Radtke 12625 5372 3887 178 21.4k
Elaine W. Raines 10337 5149 3058 141 23.1k
Shin‐Ichi Nishikawa 11402 3666 3140 172 19.0k
Lewis T. Williams 15136 4591 4106 114 21.9k
Jan Kitajewski 11483 2309 3514 178 17.4k
Peter J. Polverini 9787 4172 6081 146 20.2k
Jeffrey M. Leiden 10659 4987 2309 143 18.0k
Philippe Bouillet 10611 5585 3102 155 16.4k
M. Luisa Iruela‐Arispe 12335 2722 3037 200 21.0k
Lalage M. Wakefield 13547 3232 6889 150 23.0k
Eric W.‐F. Lam 15136 3455 5354 297 22.8k

All Works

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2026