Standout Papers

Matrix Elasticity Directs Stem Cell Lineage Specification 1999 2026 2008 2017 10.6k
  1. Matrix Elasticity Directs Stem Cell Lineage Specification (2006)
    Adam J. Engler, Shamik Sen et al. Cell
  2. Tissue Cells Feel and Respond to the Stiffness of Their Substrate (2005)
    Dennis E. Discher, Paul A. Janmey et al. Science
  3. Polymer Vesicles (2002)
    Dennis E. Discher, Adi Eisenberg Science
  4. Polymersomes: Tough Vesicles Made from Diblock Copolymers (1999)
    Bohdana M. Discher, You‐Yeon Won et al. Science
  5. Shape effects of filaments versus spherical particles in flow and drug delivery (2007)
    Yan Geng, Paul Dalhaimer et al. Nature Nanotechnology
  6. Growth Factors, Matrices, and Forces Combine and Control Stem Cells (2009)
    Dennis E. Discher, David Mooney et al. Science
  7. Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation (2013)
    Joe Swift, Irena L. Ivanovska et al. Science
  8. Myotubes differentiate optimally on substrates with tissue-like stiffness (2004)
    Adam J. Engler, Maureen A. Griffin et al. The Journal of Cell Biology
  9. Mesenchymal stem cell perspective: cell biology to clinical progress (2019)
    Mark F. Pittenger, Dennis E. Discher et al. npj Regenerative Medicine
  10. Mitotic progression following DNA damage enables pattern recognition within micronuclei (2017)
    Shane M. Harding, Joseph L. Benci et al. Nature
  11. Bio-inspired, bioengineered and biomimetic drug delivery carriers (2011)
    Jin‐Wook Yoo, Darrell J. Irvine et al. Nature Reviews Drug Discovery
  12. Substrate Compliance versus Ligand Density in Cell on Gel Responses (2004)
    Adam J. Engler, Lucie Bačáková et al. Biophysical Journal
  13. Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles (2013)
    Takamasa Harada, David A. Christian et al. Science
  14. POLYMERSOMES (2006)
    Dennis E. Discher, Fariyal Ahmed Annual Review of Biomedical Engineering
  15. Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating (2008)
    Adam J. Engler, Christine C. Krieger et al. Journal of Cell Science
  16. Physical plasticity of the nucleus in stem cell differentiation (2007)
    J. David Pajerowski, Kris Noel Dahl et al. Proceedings of the National Academy of Sciences
  17. Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance (2006)
    Mark F. Berry, Adam J. Engler et al. American Journal of Physiology-Heart and Circulatory Physiology
  18. Self-porating polymersomes of PEG–PLA and PEG–PCL: hydrolysis-triggered controlled release vesicles (2004)
    Fariyal Ahmed, Dennis E. Discher Journal of Controlled Release
  19. Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival (2014)
    Takamasa Harada, Joe Swift et al. The Journal of Cell Biology

Immediate Impact

4 by Nobel laureates 75 from Science/Nature 204 standout
Sub-graph 1 of 16

Citing Papers

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10 intermediate papers

Works of Dennis E. Discher being referenced

Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
and 5 more

Author Peers

Author Last Decade Papers Cites
Dennis E. Discher 17923 17939 20619 303 57.4k
David Mooney 18897 11551 50185 646 99.1k
Erkki Ruoslahti 43554 18662 12026 464 90.4k
Jeffrey A. Hubbell 11089 5014 18658 439 46.8k
Paul A. Janmey 13903 24019 13903 429 46.1k
Kristi S. Anseth 6633 7694 21982 437 45.2k
Donald E. Ingber 28515 26197 39217 435 86.3k
Ali Khademhosseini 11130 5026 58986 729 86.3k
Teruo Okano 12691 3160 25657 952 65.6k
Christopher S. Chen 13482 21588 26873 388 50.3k
Joachim P. Spatz 5486 8482 10673 345 25.3k

All Works

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2026