Standout Papers

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activate... 2002 2026 2010 2018 3.3k
  1. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase (2002)
    Toshimasa Yamauchi, Junji Kamon et al. Nature Medicine
  2. AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism (2005)
    Barbara B. Kahn, Thierry Alquier et al. Cell Metabolism
  3. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase (2002)
    Yasuhiko Minokoshi, Young‐Bum Kim et al. Nature
  4. LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade (2003)
    Angela Woods, Stephen R. Johnstone et al. Current Biology
  5. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism (2014)
    Gary Frost, Michelle Sleeth et al. Nature Communications
  6. THE AMP-ACTIVATED/SNF1 PROTEIN KINASE SUBFAMILY: Metabolic Sensors of the Eukaryotic Cell? (1998)
    D. Grahame Hardie, David Carling et al. Annual Review of Biochemistry
  7. Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells (2005)
    Angela Woods, Richard Heath et al. Cell Metabolism
  8. The AMP‐Activated Protein Kinase (1997)
    D. Grahame Hardie, David Carling European Journal of Biochemistry
  9. Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase (1996)
    Simon A. Hawley, Matt Davison et al. Journal of Biological Chemistry
  10. The AMP-activated protein kinase cascade – a unifying system for energy control (2003)
    David Carling Trends in Biochemical Sciences
  11. The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways (2002)
    Lee G.D. Fryer, Asha Parbhu Patel et al. Journal of Biological Chemistry
  12. Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism (1989)
    Timothy Haystead, David Carling et al. Nature
  13. Structure of mammalian AMPK and its regulation by ADP (2011)
    Bing Xiao, Matthew J. Sanders et al. Nature
  14. AMPK, insulin resistance, and the metabolic syndrome (2013)
    Neil B. Ruderman, David Carling et al. Journal of Clinical Investigation
  15. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia (2000)
    Luc Bertrand, Mark H. Rider et al. Current Biology
  16. Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype (2008)
    Duygu Sağ, David Carling et al. The Journal of Immunology
  17. AMP-activated Protein Kinase Plays a Role in the Control of Food Intake (2004)
    Ulrika Andersson‐Hall, Karin Filipsson et al. Journal of Biological Chemistry
  18. AMPK signalling in health and disease (2017)
    David Carling Current Opinion in Cell Biology
  19. Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade (2007)
    Matthew J. Sanders, Pascal Grondin et al. Biochemical Journal
  20. Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding (2000)
    Peter Cheung, Ian P. Salt et al. Biochemical Journal
  21. AMP-activated protein kinase: the current landscape for drug development (2019)
    Gregory R. Steinberg, David Carling Nature Reviews Drug Discovery
  22. Structural basis of AMPK regulation by small molecule activators (2013)
    Bing Xiao, Matthew J. Sanders et al. Nature Communications

Immediate Impact

6 by Nobel laureates 57 from Science/Nature 221 standout
Sub-graph 1 of 18

Citing Papers

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1
2023 StandoutScience
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
2020 StandoutScience
24 intermediate papers

Works of David Carling being referenced

Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
2006
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
2005 Standout
and 60 more

Author Peers

Author Last Decade Papers Cites
David Carling 28508 11822 11369 181 40.0k
Benoı̂t Viollet 26757 9541 9410 340 41.4k
Morris J. Birnbaum 27376 8271 9812 242 40.7k
Steven A. Kliewer 32561 10888 8957 166 55.4k
Christopher B. Newgard 22111 10914 15726 394 41.2k
Morris F. White 32584 12289 11383 343 50.8k
Bruce E. Kemp 30639 8619 10980 445 44.1k
David J. Mangelsdorf 39650 21964 7180 221 69.2k
Alan R. Saltiel 25052 5726 11036 279 44.7k
Barbara B. Kahn 23445 7752 19298 250 45.6k
Mitchell A. Lazar 29608 3691 16378 322 54.9k

All Works

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2026