Standout Papers

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 2010 2026 2015 2020 5.5k
  1. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 (2011)
    Joungmok Kim, Mondira Kundu et al. Nature Cell Biology
  2. Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy (2010)
    David B. Shackelford, Maria M. Mihaylova et al. Science
  3. Cellular and molecular mechanisms of metformin: an overview (2011)
    Benoı̂t Viollet, Bruno Guigas et al. Clinical Science
  4. Metformin: From Mechanisms of Action to Therapies (2014)
    Marc Foretz, Bruno Guigas et al. Cell Metabolism
  5. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state (2010)
    Marc Foretz, Sophie Hébrard et al. Journal of Clinical Investigation
  6. Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth (2007)
    Monica Buzzai, Russell G. Jones et al. Cancer Research
  7. AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo (2012)
    Brandon Faubert, Gino Boily et al. Cell Metabolism
  8. Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner (2010)
    Anand Selvaraj, So Young Kim et al. Cell Metabolism
  9. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP (2013)
    Russell Miller, Qingwei Chu et al. Nature
  10. AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol (2009)
    Sung-Jun Park, Hyeog Kang et al. Diabetes
  11. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status (2016)
    Amy Cameron, Vicky L. Morrison et al. Circulation Research
  12. The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo (2015)
    Julianna Blagih, François Coulombe et al. Immunity
  13. Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus (2019)
    Marc Foretz, Bruno Guigas et al. Nature Reviews Endocrinology
  14. AMPK in skeletal muscle function and metabolism (2017)
    Rasmus Kjøbsted, Janne R. Hingst et al. The FASEB Journal
  15. Metformin: update on mechanisms of action and repurposing potential (2023)
    Marc Foretz, Bruno Guigas et al. Nature Reviews Endocrinology

Immediate Impact

3 by Nobel laureates 38 from Science/Nature 157 standout
Sub-graph 1 of 17

Citing Papers

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1
2023 StandoutScience
Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity
2021 StandoutScience
36 intermediate papers

Works of Benoı̂t Viollet being referenced

AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR
2019
AMPKα1: A glucose sensor that controls CD8 T‐cell memory
2013
and 60 more

Author Peers

Author Last Decade Papers Cites
Benoı̂t Viollet 26757 9541 9410 10690 340 41.4k
David Carling 28508 11822 11369 8131 181 40.0k
Morris J. Birnbaum 27376 8271 9812 5560 242 40.7k
Bruce E. Kemp 30639 8619 10980 5102 445 44.1k
Barbara B. Kahn 23445 7752 19298 12110 250 45.6k
Christopher B. Newgard 22111 10914 15726 6772 394 41.2k
Domenico Accili 18571 9874 7710 4608 267 31.0k
Kristina Schoonjans 16265 7383 8068 6786 198 32.0k
Mitchell A. Lazar 29608 3691 16378 12447 322 54.9k
Morris F. White 32584 12289 11383 6402 343 50.8k
Alan R. Saltiel 25052 5726 11036 9242 279 44.7k

All Works

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2026