Standout Papers

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-r... 1998 2026 2007 2016 2.8k
  1. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells (2000)
    Hitoshi Niwa, Jun‐ichi Miyazaki et al. Nature Genetics
  2. Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 (1998)
    Jennifer Nichols, Branko Zevnik et al. Cell
  3. The ground state of embryonic stem cell self-renewal (2008)
    Qi‐Long Ying, Jason Wray et al. Nature
  4. Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells (2003)
    Ian Chambers, Douglas Colby et al. Cell
  5. BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3 (2003)
    Qi-Long Ying, Jennifer Nichols et al. Cell
  6. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides (1988)
    Austin Smith, John K. Heath et al. Nature
  7. Naive and Primed Pluripotent States (2009)
    Jennifer Nichols, Austin Smith Cell stem cell
  8. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 (1998)
    Hitoshi Niwa, Tom Burdon et al. Genes & Development
  9. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture (2003)
    Qi‐Long Ying, Marios P. Stavridis et al. Nature Biotechnology
  10. Changing potency by spontaneous fusion (2002)
    Qi‐Long Ying, Jennifer Nichols et al. Nature
  11. Nanog safeguards pluripotency and mediates germline development (2007)
    Ian Chambers, José Silva et al. Nature
  12. Altered immune responses in mice lacking inducible nitric oxide synthase (1995)
    Xiaoqing Wei, Ian G. Charles et al. Nature
  13. Embryo-Derived Stem Cells: Of Mice and Men (2001)
    Austin Smith Annual Review of Cell and Developmental Biology
  14. Nanog Is the Gateway to the Pluripotent Ground State (2009)
    José Silva, Jennifer Nichols et al. Cell
  15. Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens (2009)
    Steven M. Pollard, Koichi Yoshikawa et al. Cell stem cell
  16. Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell (2005)
    Luciano Conti, Steven M. Pollard et al. PLoS Biology
  17. Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human (2014)
    Yasuhiro Takashima, Ge Guo et al. Cell
  18. The Transcriptional and Epigenomic Foundations of Ground State Pluripotency (2012)
    Hendrik Marks, Tüzer Kalkan et al. Cell
  19. Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition (2008)
    José Silva, Ornella Barrandon et al. PLoS Biology
  20. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment (2007)
    Tilo Kunath, Marc K. Saba-El-Leil et al. Development
  21. Klf4 reverts developmentally programmed restriction of ground state pluripotency (2009)
    Ge Guo, Jian Yang et al. Development
  22. Capture of Authentic Embryonic Stem Cells from Rat Blastocysts (2008)
    Mia Buehr, Stephen Meek et al. Cell
  23. Defective Thymocyte Maturation in p44 MAP Kinase (Erk 1) Knockout Mice (1999)
    Gilles Pagès, Sandrine Guérin et al. Science
  24. Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos (1997)
    Bertold Schrank, Rudolf Götz et al. Proceedings of the National Academy of Sciences
  25. The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification (2014)
    Thorsten Boroviak, Remco Loos et al. Nature Cell Biology
  26. Human naive epiblast cells possess unrestricted lineage potential (2021)
    Ge Guo, Giuliano Giuseppe Stirparo et al. Cell stem cell

Immediate Impact

71 by Nobel laureates 117 from Science/Nature 304 standout
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Citing Papers

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel

Works of Austin Smith being referenced

Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state
2010
Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4
1998 Standout

Author Peers

Author Last Decade Papers Cites
Austin Smith 41877 5339 3039 5913 5495 219 49.3k
George Q. Daley 36199 3911 1090 5373 4703 386 49.3k
Kazutoshi Takahashi 40383 6730 2440 4728 8851 126 48.5k
James A. Thomson 49788 9827 2751 5915 10005 247 59.0k
András Nagy 29531 1989 1619 7073 4016 389 41.3k
Shinya Yamanaka 60712 10219 3815 7415 13376 276 73.6k
Janet Rossant 49358 2177 2136 11957 5341 391 61.4k
Hans R. Schöler 27118 2495 1415 5776 3631 326 32.0k
Christer Betsholtz 28465 1844 2333 3327 5839 321 51.5k
Douglas A. Melton 39607 2814 1072 13012 17445 206 53.8k
Kohei Miyazono 41161 3109 783 4216 4001 461 56.7k

All Works

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