William D. Singer

3.3k total citations · 2 hit papers
26 papers, 2.8k citations indexed

About

William D. Singer is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, William D. Singer has authored 26 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 5 papers in Cell Biology and 5 papers in Physiology. Recurrent topics in William D. Singer's work include Protein Kinase Regulation and GTPase Signaling (13 papers), Nitric Oxide and Endothelin Effects (4 papers) and Cellular transport and secretion (4 papers). William D. Singer is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (13 papers), Nitric Oxide and Endothelin Effects (4 papers) and Cellular transport and secretion (4 papers). William D. Singer collaborates with scholars based in United States, Japan and Canada. William D. Singer's co-authors include Paul C. Sternweis, H. Alex Brown, Tohru Kozasa, Gideon Bollag, Alfred G. Gilman, Matthew J. Hart, Xuejun Jiang, Xuejun Jiang, R. Tyler Miller and Zhe Chen and has published in prestigious journals such as Science, Journal of Biological Chemistry and Neuron.

In The Last Decade

William D. Singer

26 papers receiving 2.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 730 citations Tohru Kozasa, Xuejun Jiang et al. Science profile →
Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 664 citations Matthew J. Hart, Xuejun Jiang et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William D. Singer United States	20	2.3k	746	295	276	276	26	2.8k
E.J. van Corven Netherlands	14	2.6k 1.2×	809 1.1×	415 1.4×	190 0.7×	550 2.0×	15	3.2k
George Tokiwa United States	14	2.8k 1.2×	764 1.0×	226 0.8×	408 1.5×	168 0.6×	19	3.4k
Kathryn E. Meier United States	33	2.2k 0.9×	550 0.7×	380 1.3×	258 0.9×	366 1.3×	85	3.0k
Louise Larose Canada	29	1.4k 0.6×	607 0.8×	275 0.9×	226 0.8×	203 0.7×	74	2.3k
Néstor Gómez Spain	24	2.7k 1.2×	593 0.8×	449 1.5×	436 1.6×	158 0.6×	46	3.4k
Maria Rozakis-Adcock Canada	22	2.2k 1.0×	663 0.9×	216 0.7×	605 2.2×	234 0.8×	23	3.0k
Jean‐Luc Parent Canada	29	1.8k 0.8×	389 0.5×	604 2.0×	353 1.3×	253 0.9×	65	2.4k
Daniel M. Raben United States	29	2.2k 0.9×	629 0.8×	242 0.8×	385 1.4×	443 1.6×	75	3.0k
Anthony Rossomando United States	24	2.2k 0.9×	424 0.6×	382 1.3×	332 1.2×	209 0.8×	39	2.9k
Guy L. James United States	15	2.2k 1.0×	738 1.0×	160 0.5×	619 2.2×	163 0.6×	19	2.6k

Countries citing papers authored by William D. Singer

Since Specialization

Citations

This map shows the geographic impact of William D. Singer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William D. Singer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William D. Singer more than expected).

Fields of papers citing papers by William D. Singer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William D. Singer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William D. Singer. The network helps show where William D. Singer may publish in the future.

Co-authorship network of co-authors of William D. Singer

This figure shows the co-authorship network connecting the top 25 collaborators of William D. Singer. A scholar is included among the top collaborators of William D. Singer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William D. Singer. William D. Singer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Harshbarger, Wayne, Sudershan Reddy Gondi, Scott B. Ficarro, et al.. (2016). Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine. Journal of Biological Chemistry. 292(1). 112–120. 72 indexed citations

Tan, Li, Deepak Gurbani, Ellen Weisberg, et al.. (2016). Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. 25(4). 1320–1328. 18 indexed citations

Singer, William D., et al.. (2013). Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice. DNA repair. 12(10). 817–823. 9 indexed citations

Chen, Zhe, et al.. (2008). Recognition of the Activated States of Gα13 by the rgRGS Domain of PDZRhoGEF. Structure. 16(10). 1532–1543. 39 indexed citations

Sternweis, Paul C., et al.. (2007). Regulation of Rho Guanine Nucleotide Exchange Factors by G Proteins. Advances in protein chemistry. 74. 189–228. 44 indexed citations

Chen, Zhe, William D. Singer, Paul C. Sternweis, & Stephen R. Sprang. (2005). Structure of the p115RhoGEF rgRGS domain–Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator. Nature Structural & Molecular Biology. 12(2). 191–197. 87 indexed citations

Al‐Gahtany, Mubarak, Michael D. Cusimano, William D. Singer, et al.. (2003). Brown tumors of the skull base. Journal of neurosurgery. 98(2). 417–420. 25 indexed citations

Chen, Zhe, William D. Singer, Clark D. Wells, Stephen R. Sprang, & Paul C. Sternweis. (2003). Mapping the Gα13 Binding Interface of the rgRGS Domain of p115RhoGEF. Journal of Biological Chemistry. 278(11). 9912–9919. 36 indexed citations

Jiang, Xuejun, Stephen Gutowski, William D. Singer, & Paul C. Sternweis. (2002). Assays and Characterization of Mammalian Phosphatidylinositol 4,5-Bisphosphate-Sensitive Phospholipase D. Methods in enzymology on CD-ROM/Methods in enzymology. 345. 328–334. 7 indexed citations

10.

Kitamura, Kenichiro, Naoki Shiraishi, William D. Singer, et al.. (1999). Endothelin-B receptors activate Gα₁₃. American Journal of Physiology-Cell Physiology. 276(4). C930–C937. 38 indexed citations

11.

Kozasa, Tohru, Xuejun Jiang, Matthew J. Hart, et al.. (1998). p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃. Science. 280(5372). 2109–2111. 730 indexed citations breakdown →

12.

Singer, William D., H. Alex Brown, Xuejun Jiang, & Paul C. Sternweis. (1996). Regulation of Phospholipase D by Protein Kinase C Is Synergistic with ADP-ribosylation Factor and Independent of Protein Kinase Activity. Journal of Biological Chemistry. 271(8). 4504–4510. 214 indexed citations

13.

Kitamura, Kenichiro, William D. Singer, Robert A. Star, Shmuel Muallem, & R. Tyler Miller. (1996). Induction of Inducible Nitric-oxide Synthase by the Heterotrimeric G Protein Gα13*. Journal of Biological Chemistry. 271(13). 7412–7415. 62 indexed citations

14.

Singer, William D., H. Alex Brown, Gary Bokoch, & Paul C. Sternweis. (1995). Resolved Phospholipase D Activity Is Modulated by Cytosolic Factors Other than Arf. Journal of Biological Chemistry. 270(25). 14944–14950. 115 indexed citations

15.

Singer, William D., et al.. (1994). The G protein G13 mediates inhibition of voltage-dependent calcium current by bradykinin. Neuron. 13(5). 1215–1224. 38 indexed citations

16.

Singer, William D., et al.. (1994). Polymerization of Antarctic Fish Tubulins at Low Temperatures: Role of Carboxy-Terminal Domains. Biochemistry. 33(51). 15389–15396. 4 indexed citations

17.

Singer, William D. & Richard H. Himes. (1992). Cellular uptake and tubulin binding properties of four vinca alkaloids. Biochemical Pharmacology. 43(3). 545–551. 39 indexed citations

18.

Singer, William D., Mary Ann Jordan, L Wilson, & Richard H. Himes. (1989). Binding of vinblastine to stabilized microtubules.. Molecular Pharmacology. 36(3). 366–370. 39 indexed citations

19.

Singer, William D., R.T. Hersh, & Richard H. Himes. (1988). Effect of solution variables on the binding of vinblastine to tubulin. Biochemical Pharmacology. 37(13). 2691–2696. 20 indexed citations

20.

Becker, Clifford A. L., William D. Singer, & Eric M. Towler. (1986). Preparation of tetrakis(arylisocyanide)trialkylphosphitecobalt(I) complexes with sterically-hindered arylisocyanides. Inorganica Chimica Acta. 113(1). 75–79. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact