Timothy J. Opperman

2.3k citations

36 papers · 1.7k · h-index 22

Impact in

Molecular Medicine top 0.5%
- Antibiotic Resistance in Bacteria
Microbiology top 5%

Papers in

Molecular Biology 19
- DNA Repair Mechanisms 5
- RNA and protein synthesis mechanisms 5
- Cancer therapeutics and mechanisms 5
Molecular Medicine 14
- Antibiotic Resistance in Bacteria 14

Co-authors: Son T. Nguyen (6 shared papers)Steven M. Kwasny (8 shared papers)Graham C. Walker (6 shared papers)Terry L. Bowlin (15 shared papers)Hiroshi Nikaido (4 shared papers)Sumati Murli (4 shared papers)Zachary D. Aron (5 shared papers)B T Smith (2 shared papers)
Journals: Antimicrobial Agents and Chemotherapy (5 papers)Journal of Bacteriology (4 papers)Antiviral Research (3 papers)Proceedings of the National Academy of Sciences (3 papers)Bioorganic & Medicinal Chemistry (3 papers)
Partner nations: United States Italy United Kingdom

In The Last Decade

Timothy J. Opperman

36 papers receiving 1.7k citations

Peers

Countries citing papers authored by Timothy J. Opperman

Since Specialization

Citations

This map shows the geographic impact of Timothy J. Opperman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy J. Opperman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy J. Opperman more than expected).

Fields of papers citing papers by Timothy J. Opperman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy J. Opperman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy J. Opperman. The network helps show where Timothy J. Opperman may publish in the future.

Co-authors

The 25 scholars most cited alongside Timothy J. Opperman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Timothy J. Opperman Line = papers co-authored together Timothy J. Opperman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 36 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Recent advances toward a molecular mechanism of efflux pump inhibition Frontiers in Microbiology ·Timothy J. Opperman, Son T. Nguyen	2015	217
2	Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives Proceedings of the National Academy of Sciences ·Hanno Sjuts, Attilio V. Vargiu, Steven M. Kwasny, Son T. Nguyen, Hong‐Suk Kim, Xiaoyuan Ding, A.R. Ornik, Paolo Ruggerone, Terry L. Bowlin, Hiroshi Nikaido, Klaas M. Pos, Timothy J. Opperman	2016	163
3	Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli Antimicrobial Agents and Chemotherapy ·Timothy J. Opperman, Steven M. Kwasny, Hong‐Suk Kim, Son T. Nguyen, Chad Houseweart, Sanjay D’Souza, Graham C. Walker, Norton P. Peet, Hiroshi Nikaido, Terry L. Bowlin	2013	155
4	A model for a umuDC -dependent prokaryotic DNA damage checkpoint Proceedings of the National Academy of Sciences ·Timothy J. Opperman, Sumati Murli, B T Smith, Graham C. Walker	1999	138
5	Molecular Mechanism of MBX2319 Inhibition of Escherichia coli AcrB Multidrug Efflux Pump and Comparison with Other Inhibitors Antimicrobial Agents and Chemotherapy ·Attilio V. Vargiu, Paolo Ruggerone, Timothy J. Opperman, Son T. Nguyen, Hiroshi Nikaido	2014	132
6	Static Biofilm Cultures of Gram‐Positive Pathogens Grown in a Microtiter Format Used for Anti‐Biofilm Drug Discovery Current Protocols in Pharmacology ·Steven M. Kwasny, Timothy J. Opperman	2010	132
7	Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium mBio ·Xuan Wang‐Kan, Jessica M. A. Blair, Barbara Chirullo, Jonathan W. Betts, Roberto M. La Ragione, Alasdair Ivens, Vito Ricci, Timothy J. Opperman, Laura J. V. Piddock	2017	101
8	The Escherichia coli SOS mutagenesis proteins UmuD and UmuD′ interact physically with the replicative DNA polymerase Proceedings of the National Academy of Sciences ·Mark D. Sutton, Timothy J. Opperman, Graham C. Walker	1999	88
9	Structure–activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors Bioorganic & Medicinal Chemistry ·Son T. Nguyen, Steven M. Kwasny, Xiaoyuan Ding, Steven C. Cardinale, Courtney T. McCarthy, Hong‐Suk Kim, Hiroshi Nikaido, Norton P. Peet, John D. Williams, Terry L. Bowlin, Timothy J. Opperman	2015	65
10	Phylogenetic analysis of sequences from diverse bacteria with homology to the Escherichia coli rho gene Journal of Bacteriology ·Timothy J. Opperman, J P Richardson	1994	62
11	Mutational Analysis and Secondary Structure Model of the RNP1-like Sequence Motif of Transcription Termination Factor Rho Journal of Molecular Biology ·Asunción Martínez Martínez, Timothy J. Opperman, John P. Richardson	1996	40
12	The hydrophobic trap—the Achilles heel of RND efflux pumps Research in Microbiology ·Zachary D. Aron, Timothy J. Opperman	2017	39
13	Optimization of a novel series of pyranopyridine RND efflux pump inhibitors Current Opinion in Microbiology ·Zachary D. Aron, Timothy J. Opperman	2016	38
14	The genetic requirements for UmuDC-mediated cold sensitivity are distinct from those for SOS mutagenesis Journal of Bacteriology ·Timothy J. Opperman, Sumati Murli, Graham C. Walker	1996	36
15	A Role for the umuDC Gene Products of Escherichia coli in Increasing Resistance to DNA Damage in Stationary Phase by Inhibiting the Transition to Exponential Growth Journal of Bacteriology ·Sumati Murli, Timothy J. Opperman, B T Smith, Graham C. Walker	2000	35
16	A High-Throughput, Homogeneous, Bioluminescent Assay for Pseudomonas aeruginosa Gyrase Inhibitors and Other DNA-Damaging Agents SLAS DISCOVERY ·Donald T. Moir, Di Ming, Timothy J. Opperman, Herbert P. Schweizer, Terry L. Bowlin	2007	34
17	New classes of antibiotics Current Opinion in Pharmacology ·Donald T. Moir, Timothy J. Opperman, Michelle M. Butler, Terry L. Bowlin	2012	33
18	trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo Nature Communications ·Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, Kristie L. Connolly, Pooja Srinivas, Matthew C. Torhan, John N. Alumasa, Mynthia Cabrera, Divya Hosangadi, Jay S. Barbor, Steven C. Cardinale, Steven M. Kwasny, Lucas R. Morin, Michelle M. Butler, Timothy J. Opperman, Terry L. Bowlin, Ann E. Jerse, Scott M. Stagg, C.M. Dunham, Kenneth C. Keiler	2021	31
19	Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: Synthesis and SAR of novel analogs of MBX 1066 and MBX 1090 Bioorganic & Medicinal Chemistry ·John D. Williams, Son T. Nguyen, Shen Gu, Xiaoyuan Ding, Michelle M. Butler, Tommy F. Tashjian, Timothy J. Opperman, Rekha G. Panchal, Sina Bavari, Norton P. Peet, Donald T. Moir, Terry L. Bowlin	2013	29
20	umuDC-dnaQ Interaction and Its Implications for Cell Cycle Regulation and SOS Mutagenesis in Escherichia coli Journal of Bacteriology ·Mark D. Sutton, Sumati Murli, Timothy J. Opperman, Carly Klein, Graham C. Walker	2001	26

About Timothy J. Opperman

Timothy J. Opperman is a scholar working on Molecular Biology, Molecular Medicine, Genetics, Epidemiology and Infectious Diseases, having authored 36 papers that have together received 1.7k indexed citations. Recurring topics across this work include Antibiotic Resistance in Bacteria (14 papers), Bacterial Genetics and Biotechnology (12 papers), DNA Repair Mechanisms (5 papers), RNA and protein synthesis mechanisms (5 papers), Cancer therapeutics and mechanisms (5 papers), Cytomegalovirus and herpesvirus research (4 papers), Tuberculosis Research and Epidemiology (4 papers) and Antibiotics Pharmacokinetics and Efficacy (3 papers). The work is most often cited by research in Molecular Medicine (738 citations), Microbiology (128 citations), Endocrinology (101 citations), Genetics (439 citations) and Pharmacology (246 citations). Timothy J. Opperman has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Son T. Nguyen, Steven M. Kwasny, Graham C. Walker, Terry L. Bowlin, Hiroshi Nikaido, Sumati Murli, Zachary D. Aron, B T Smith, Paolo Ruggerone and Attilio V. Vargiu. Their work appears in journals such as Antimicrobial Agents and Chemotherapy, Journal of Bacteriology, Antiviral Research, Proceedings of the National Academy of Sciences and Bioorganic & Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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