Thomas J. Wickham

11.2k citations

95 papers · 9.0k indexed · 2 hit papers · h-index 47

Impact in

Genetics top 0.1%
- Virus-based gene therapy research
Oncology top 0.5%
- CAR-T cell therapy research

Papers in

Genetics 56
- Virus-based gene therapy research 55
Oncology 52
- CAR-T cell therapy research 33
- HER2/EGFR in Cancer Research 17
- Cancer Treatment and Pharmacology 9

Co-authors: Glen R. Nemerow Imre Kovesdi David A. Cheresh Patricia Mathias Peter W. Roelvink Douglas E. Brough Alena Lizonová Jeffrey M. Bergelson
Journals: Journal of Virology (17 papers)Cancer Research (10 papers)Human Gene Therapy (7 papers)Gene Therapy (4 papers)Molecular Cancer Therapeutics (4 papers)
Partner nations: United States Canada France

In The Last Decade

Thomas J. Wickham

94 papers receiving 8.8k citations

Hit Papers

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The Coxsackievirus-Adenovirus Receptor Protein Can Function as a Cellular Attachment Protein for Adenovirus Serotypes from Subgroups A, C, D, E, and F 1998 · 524 citations

Peers

Countries citing papers authored by Thomas J. Wickham

Since Specialization

Citations

This map shows the geographic impact of Thomas J. Wickham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas J. Wickham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas J. Wickham more than expected).

Fields of papers citing papers by Thomas J. Wickham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas J. Wickham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas J. Wickham. The network helps show where Thomas J. Wickham may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Thomas J. Wickham, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas J. Wickham Line = papers co-authored together Thomas J. Wickham links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Safety and pharmacokinetics of MM-302, a HER2-targeted antibody–liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: a phase 1 dose-escalation study British Journal of Cancer ·Pamela N. Münster, Ian E. Krop, Patricia LoRusso, X. Cynthia, Barry A. Siegel, Anthony F. Shields, István Molnár, Thomas J. Wickham, Joseph G. Reynolds, Karen Campbell, Bart S. Hendriks, Bambang S. Adiwijaya, Elena Geretti, Victor Moyo, Kathy D. Miller	2018	95
2	Quantitative evaluation of HER2-mediated cellular uptake of the HER2-targeted antibody-liposomal doxorubicin conjugate MM-302 suggests potential for treating HER2-intermediate tumors Annals of Oncology ·Elena Geretti, Maria Elena Ascioti, Pepijn Corduwener, Nancy Dumont, Sílvia Coma, 婉钰周, Gabriela Garcia, Troy Bloom, Victoria Rimkunas, John V. Reynolds, Karen Campbell, Christa Youngpeter, István Molnár, Patricia LoRusso, I. K. Dvorianinova, X. Cynthia, Ian E. Krop, Pamela N. Münster, Thomas J. Wickham	2016	1
3	Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer Cancer Research ·Christopher W. Espelin, Shannon C. Leonard, Elena Geretti, Thomas J. Wickham, Bart S. Hendriks	2016	96
4	Whole-body organ-level and kidney micro-dosimetric evaluations of 64Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin (64Cu-MM-302) in rodents and primates EJNMMI Research ·Daniel F. Gaddy, Helen Lee, Jinzi Zheng, David A. Jaffray, Thomas J. Wickham, Bart S. Hendriks	2015	15
5	PET/CT Imaging of 64CU-Labelled HER2 Liposomal Doxorubicin (64CU-MM-302) Quantifies Variability of Liposomal Drug Delivery to Diverse Tumor Lesions in HER2-Positive Breast Cancer Patients Annals of Oncology ·Bart S. Hendriks, Anthony F. Shields, Barry A. Siegel, Kathy D. Miller, Pamela N. Münster, X. Cynthia, Karen Campbell, Christa Youngpeter, Thomas J. Wickham, P. LoRusso	2014	10
6	Single-Cell Quantitative HER2 Measurement Identifies Heterogeneity and Distinct Subgroups within Traditionally Defined HER2-Positive Patients American Journal Of Pathology ·Matthew Onsum, Elena Geretti, Violette Paragas, Arthur J. Kudla, محمد ابونجمی, Lia Luus, Thomas J. Wickham, Charlotte F. McDonagh, Gavin MacBeath, Bart S. Hendriks	2013	72
7	HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity Toxicology and Applied Pharmacology ·Joseph G. Reynolds, Elena Geretti, Bart S. Hendriks, Helen Lee, Shannon C. Leonard, Stephan G. Klinz, Charles O. Noble, Siyuan Wang, Peter W. Zandstra, Daryl C. Drummond, Kenneth J. Olivier, Ulrik B. Nielsen, Clet Niyikiza, Samuel Agresta, Thomas J. Wickham	2012	93
8	Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid Journal of Clinical Investigation ·Stefan Worgall, Anja Krause, El-Dahabi Farouk Wahid, Ben Smeele, Killian Jampierre, Neil R. Hackett, Peter W. Roelvink, Joseph T. Bruder, Thomas J. Wickham, Imre Kovesdi, Ronald G. Crystal	2005	89
9	Comparison of Different Cell Lines for the Production of Recombinant Baculovirus Proteins Humana Press eBooks ·Thomas J. Wickham, Glen R. Nemerow, H. A. Wood, Michael L. Shuler	2003	7
10	Ablating CAR and Integrin Binding in Adenovirus Vectors Reduces Nontarget Organ Transduction and Permits Sustained Bloodstream Persistence Following Intraperitoneal Administration Molecular Therapy ·Masaki Akiyama, Stephen H. Thorne, David H. Kirn, Peter W. Roelvink, David A. Einfeld, C. Richter King, Thomas J. Wickham	2003	46
11	Receptor-mediated targeting of gene delivery vectors: Insights from molecular mechanisms for improved vehicle design Biotechnology and Bioengineering ·Daphne Read, Thomas J. Wickham, Douglas A. Lauffenburger	2000	92
12	Extended tropism of an adenoviral vector does not circumvent the maturation-dependent transducibility of mouse skeletal muscle The Journal of Gene Medicine ·J.C.T. van Deutekom, Baohong Cao, Ryan Pruchnic, Thomas J. Wickham, Imre Kovesdi, Johnny Huard	1999	24
13	CAR-dependent and CAR-independent pathways of adenovirus vector–mediated gene transfer and expression in human fibroblasts Journal of Clinical Investigation ·Chisa Hidaka, 真美加古, Philip L. Leopold, Jeffrey M. Bergelson, Neil R. Hackett, Robert W. Finberg, Thomas J. Wickham, Imre Kovesdi, Peter Roelvink, Ronald G. Crystal	1999	179
14	Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin Gene Therapy ·Olivier Harari, Thomas J. Wickham, Dylana Diaz-Solano, Imre Kovesdi, David M. Segal, Tanya Y. Huehns, Catherine Sarraf, Dorian O. Haskard	1999	67
15	Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types Nature Biotechnology ·Thomas J. Wickham, Peter W. Roelvink, Douglas E. Brough, Imre Kovesdi	1996	276
16	Adenovirus entry into host cells: a role for αv integrins Trends in Cell Biology ·Glen R. Nemerow, David A. Cheresh, Thomas J. Wickham	1994	50
17	Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment Cell ·Thomas J. Wickham, Patricia Mathias, David A. Cheresh, Glen R. Nemerow Hit paper breakdown →	1993	1820
18	Comparative recombinant protein production of eight insect cell lines In Vitro Cellular & Developmental Biology - Animal ·Thomas R. Davis, Thomas J. Wickham, Prof. Steven N. Shore, Robert R. Granados, Michael L. Shuler, H. A. Wood	1993	139
19	Equilibrium and kinetic analysis of Autographa californica nuclear polyhedrosis virus attachment to different insect cell lines Journal of General Virology ·Thomas J. Wickham, Michael L. Shuler, Daniel A. Hammer, Robert R. Granados, H. A. Wood	1992	44
20	General analysis of receptor-mediated viral attachment to cell surfaces Biophysical Journal ·Thomas J. Wickham, Robert R. Granados, H. A. Wood, Daniel A. Hammer, Michael L. Shuler	1990	75

About Thomas J. Wickham

Thomas J. Wickham is a scholar working on Genetics, Oncology, Radiology, Nuclear Medicine and Imaging, Biotechnology and Molecular Biology, having authored 95 papers that have together received 9.0k indexed citations. Recurring topics across this work include Virus-based gene therapy research (55 papers), CAR-T cell therapy research (33 papers), Viral Infectious Diseases and Gene Expression in Insects (24 papers), RNA Interference and Gene Delivery (23 papers), Monoclonal and Polyclonal Antibodies Research (18 papers), HER2/EGFR in Cancer Research (17 papers), Viral gastroenteritis research and epidemiology (11 papers) and Cancer Treatment and Pharmacology (9 papers). The work is most often cited by research in Genetics (6.3k citations), Oncology (3.1k citations), Molecular Biology (5.9k citations), Infectious Diseases (1.4k citations) and Biotechnology (515 citations). Thomas J. Wickham has collaborated with scholars based in United States, Canada and France. Frequent co-authors include Glen R. Nemerow, Imre Kovesdi, David A. Cheresh, Patricia Mathias, Peter W. Roelvink, Douglas E. Brough, Alena Lizonová, Jeffrey M. Bergelson, David A. Einfeld and Robert W. Finberg. Their work appears in journals such as Journal of Virology, Cancer Research, Human Gene Therapy, Gene Therapy and Molecular Cancer Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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