Thomas E. Hughes

4.9k total citations · 2 hit papers
64 papers, 3.1k citations indexed

About

Thomas E. Hughes is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Biophysics. According to data from OpenAlex, Thomas E. Hughes has authored 64 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 37 papers in Cellular and Molecular Neuroscience and 29 papers in Biophysics. Recurrent topics in Thomas E. Hughes's work include Advanced Fluorescence Microscopy Techniques (29 papers), Photoreceptor and optogenetics research (21 papers) and Retinal Development and Disorders (15 papers). Thomas E. Hughes is often cited by papers focused on Advanced Fluorescence Microscopy Techniques (29 papers), Photoreceptor and optogenetics research (21 papers) and Retinal Development and Disorders (15 papers). Thomas E. Hughes collaborates with scholars based in United States, Estonia and Canada. Thomas E. Hughes's co-authors include Mikhail Drobizhev, Aleksander Rebane, Nikolay S. Makarov, Shane Tillo, Peter Novick, Marc Pypaert, Charles O. Boyd, James O McNamara, Keith A. Cauley and Lorise C. Gahring and has published in prestigious journals such as Science, New England Journal of Medicine and The Journal of Cell Biology.

In The Last Decade

Thomas E. Hughes

64 papers receiving 3.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Two-photon absorption properties of fluorescent proteins

2011 533 citations Mikhail Drobizhev, Nikolay S. Makarov et al. Nature Methods profile →
Autoantibodies to Glutamate Receptor GluR3 in Rasmussen's Encephalitis

1994 512 citations Thomas E. Hughes et al. profile →

Peers

Countries citing papers authored by Thomas E. Hughes

Since Specialization

Citations

This map shows the geographic impact of Thomas E. Hughes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas E. Hughes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas E. Hughes more than expected).

Fields of papers citing papers by Thomas E. Hughes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas E. Hughes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas E. Hughes. The network helps show where Thomas E. Hughes may publish in the future.

Co-authorship network of co-authors of Thomas E. Hughes

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas E. Hughes. A scholar is included among the top collaborators of Thomas E. Hughes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas E. Hughes. Thomas E. Hughes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Advanced Model-based Approach to Evaluate Human Plasma, Cerebrospinal Fluid, and Neuronal mTORC1 Activation Biomarkers After NV-5138 Administration in Healthy Volunteers 2024 ·Clinical Therapeutics ·(unknown), J. Randall Owen, Roberto Goméni, Alisa R. Kosheleff, Jeanelle Portelli, (unknown), Thomas E. Hughes	1
2	An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice 2020 ·Nature Chemical Biology ·Jinfan Zhang, Bian Liu, Ingie Hong, (unknown), Richard H. Roth, Brian Tenner, Wei Lin, Jason Z. Zhang, Rosana S. Molina, Mikhail Drobizhev, Thomas E. Hughes, Lin Tian, Richard L. Huganir, Sohum Mehta, Jin Zhang	71
3	High throughput instrument to screen fluorescent proteins under two-photon excitation 2020 ·Biomedical Optics Express ·Rosana S. Molina, Jonathan King, (unknown), Nathan Clack, (unknown), (unknown), Daniel Flickinger, Karel Svoboda, Mikhail Drobizhev, Thomas E. Hughes	5
4	A genetically encoded near-infrared fluorescent calcium ion indicator 2019 ·Nature Methods ·Yong Qian, Kiryl D. Piatkevich, Benedict Mc Larney, Ahmed S. Abdelfattah, Sohum Mehta, Mitchell H. Murdock, Sven Gottschalk, Rosana S. Molina, Wei Zhang, Yingche Chen, Jiahui Wu, Mikhail Drobizhev, Thomas E. Hughes, Jin Zhang, Eric R. Schreiter, Shy Shoham, Daniel Razansky, Edward S. Boyden, Robert E. Campbell	162
5	Live-Cell Assays for Cell Stress Responses Reveal New Patterns of Cell Signaling Caused by Mutations in Rhodopsin, α-Synuclein and TDP-43 2019 ·Frontiers in Cellular Neuroscience ·Kevin Harlen, (unknown), Joseph E. Clayton, Scott Martinka, Thomas E. Hughes	7
6	Assay for Detecting Gαi-Mediated Decreases in cAMP in Living Cells 2018 ·SLAS DISCOVERY ·Paul Tewson, Scott Martinka, Nathan C. Shaner, Catherine H. Berlot, Anne Marie Quinn, Thomas E. Hughes	11
7	Near-Infrared Fluorescent Proteins Engineered from Bacterial Phytochromes in Neuroimaging 2017 ·Biophysical Journal ·Kiryl D. Piatkevich, Ho-Jun Suk, Suhasa B. Kodandaramaiah, Fumiaki Yoshida, Ellen M. DeGennaro, Mikhail Drobizhev, Thomas E. Hughes, Robert Desimone, Edward S. Boyden, Vladislav V. Verkhusha	42
8	Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange 2015 ·Nature Methods ·Yidan Ding, Jiao Li, Jhon R. Enterina, Yi Shen, Issan Zhang, Paul Tewson, Gary Mo, Jin Zhang, Anne Marie Quinn, Thomas E. Hughes, Dušica Maysinger, Spencer C. Alford, Yan Zhang, Robert E. Campbell	121
9	Green Fluorescent Protein with Anionic Tryptophan-Based Chromophore and Long Fluorescence Lifetime 2015 ·Biophysical Journal ·Karen S. Sarkisyan, (unknown), Peter V. Lidsky, D.A. Gorbachev, Nina G. Bozhanova, Andrey Yu. Gorokhovatsky, (unknown), (unknown), (unknown), Alexander P. Savitsky, Kyril M. Solntsev, Andreas S. Bommarius, Г. В. Шаронов, (unknown), Mikhail Drobizhev, Thomas E. Hughes, Aleksander Rebane, Konstantin A. Lukyanov, Alexander S. Mishin	53
10	Improving Signal Dynamics of Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions 2015 ·Biophysical Journal ·Uhna Sung, Lei Jin, Thomas E. Hughes, Lawrence B. Cohen, Bradley J. Baker, (unknown)	3
11	The Two-Photon Bazooka: A New Way of Optically Screening Randomly Mutagenized Libraries of Fluorescent Proteins 2014 ·Biophysical Journal ·(unknown), Caleb Stoltzfus, Geoffrey Wicks, Mikhail Drobizhev, (unknown), Aleksander Rebane, Thomas E. Hughes	1
12	A Multiplexed Fluorescent Assay for Independent Second-Messenger Systems: Decoding GPCR Activation in Living Cells 2013 ·SLAS DISCOVERY ·Paul Tewson, Anne Marie Quinn, Thomas E. Hughes	20
13	Simultaneous Detection of Ca2+ and Diacylglycerol Signaling in Living Cells 2012 ·PLoS ONE ·Paul Tewson, (unknown), Yongxin Zhao, Robert E. Campbell, Anne Marie Quinn, Thomas E. Hughes	42
14	Primary Role of the Chromophore Bond Length Alternation in Reversible Photoconversion of Red Fluorescence Proteins 2012 ·Scientific Reports ·Mikhail Drobizhev, Thomas E. Hughes, Yuriy Stepanenko, Paweł Wnuk, Kieran J. O’Donnell, (unknown), Patrik R. Callis, Alexander Mikhaylov, (unknown), Aleksander Rebane	27
15	Two-photon absorption properties of fluorescent proteins breakdown → 2011 ·Nature Methods ·Mikhail Drobizhev, Nikolay S. Makarov, Shane Tillo, Thomas E. Hughes, Aleksander Rebane	533
16	Color Hues in Fluorescent Proteins with the Same Chromophore are due to Internal Quadratic Stark Effect 2010 ·Biophysical Journal ·Mikhail Drobizhev, Shane Tillo, Nikolay S. Makarov, Aleksander Rebane, Thomas E. Hughes	1
17	Absolute Two-photon Absorption Spectra Of Orange And Red Fluorescent Proteins 2009 ·Biophysical Journal ·Mikhail Drobizhev, Shane Tillo, Nikolay S. Makarov, Aleksander Rebane, Thomas E. Hughes	1
18	Ionotropic glutamate receptors in the retina: Moving from molecules to circuits 1998 ·Vision Research ·(unknown), Raymond Molloy, Thomas E. Hughes	21
19	Developmental and sensory-dependent changes of phosphoinositide-linked metabotropic glutamate receptors 1997 ·The Journal of Comparative Neurology ·Silvia N.M. Reid, Carmelo Romano, Thomas E. Hughes, Nigel W. Daw	29
20	Transmembrane topology of the glutamate receptors 1994 ·Journal of Molecular Neuroscience ·Thomas E. Hughes	6

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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