Thomas C. Spelsberg

22.7k citations

264 papers · 17.8k indexed · 5 hit papers · h-index 68

Impact in

Orthopedics and Sports Medicine top 0.1%
- Bone health and osteoporosis research
Genetics top 0.1%
- Estrogen and related hormone effects

Papers in

Genetics 105
- Estrogen and related hormone effects 86
Molecular Biology 168
- Bone Metabolism and Diseases 62
- TGF-β signaling in diseases 34
- DNA and Nucleic Acid Chemistry 28
- RNA Research and Splicing 16
- Genomics and Chromatin Dynamics 16

Co-authors: B. Lawrence Riggs Malayannan Subramaniam Sundeep Khosla Lorenz C. Hofbauer Colin R. Dunstan Merry Jo Oursler Douglas S. Colvard Steven A. Harris
Journals: Journal of Cellular Biochemistry (25 papers)Endocrinology (25 papers)Journal of Bone and Mineral Research (17 papers)Biochemistry (14 papers)American Journal of Obstetrics and Gynecology (10 papers)
Partner nations: United States France Canada

In The Last Decade

Thomas C. Spelsberg

262 papers receiving 16.8k citations

Hit Papers

5 papers align trajectories log scale

Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype 2003 · 545 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2003 Circulation
1999 Bone
1999 Endocrinology
1999 Endocrinology
1988 Science

Peers

Countries citing papers authored by Thomas C. Spelsberg

Since Specialization

Citations

This map shows the geographic impact of Thomas C. Spelsberg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas C. Spelsberg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas C. Spelsberg more than expected).

Fields of papers citing papers by Thomas C. Spelsberg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas C. Spelsberg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas C. Spelsberg. The network helps show where Thomas C. Spelsberg may publish in the future.

Co-authors

The 25 scholars most cited alongside Thomas C. Spelsberg, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas C. Spelsberg Line = papers co-authored together Thomas C. Spelsberg links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	2‐methoxyestradiol‐mediated anti‐tumor effect increases osteoprotegrin expression in osteosarcoma cells Journal of Cellular Biochemistry ·Michaela Benedikt, Eric Mahlum, Kristen L. Shogren, Malayannan Subramaniam, Thomas C. Spelsberg, Michael J. Yaszemski, Avudaiappan Maran	2010	12
2	The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1 Nature Immunology ·K. Venuprasad, Haining Huang, Yohsuke Harada, Chris Elly, Malayannan Subramaniam, Thomas C. Spelsberg, Jin Su, Yun‐Cai Liu	2008	144
3	Estrogen‐TGFβ cross‐talk in bone and other cell types: Role of TIEG, Runx2, and other transcription factors Journal of Cellular Biochemistry ·John R. Hawse, Malayannan Subramaniam, James N. Ingle, Merry Jo Oursler, Nalini M. Rajamannan, Thomas C. Spelsberg	2007	45
4	Age-dependent changes in the mechanical properties of tail tendons in TGF-β inducible early gene-1 knockout mice Journal of Applied Physiology ·Sabine F. Bensamoun, Tetsu Tsubone, Malayannan Subramaniam, John R. Hawse, Emir Boumediene, Thomas C. Spelsberg, Kai-Nan An, Peter C. Amadio	2006	26
5	Overexpression of the TGF-β antagonist Smad7 in endometrial cancer Gynecologic Oncology ·Sean C. Dowdy, Andrea Mariani, Monica M. Reinholz, Gary L. Keeney, Thomas C. Spelsberg, Karl C. Podratz, Ralf Janknecht	2004	46
6	Differential Gene Expression of TGFβ Inducible Early Gene (TIEG), Smad7, Smad2 and Bard1 in Normal and Malignant Breast Tissue Breast Cancer Research and Treatment ·Monica M. Reinholz, Ming-Wen An, Steven A. Johnsen, Malayannan Subramaniam, Vera J. Suman, James N. Ingle, Patrick C. Roche, Thomas C. Spelsberg	2004	50
7	Primer on Medical Genomics Part III: Microarray Experiments and Data Analysis Mayo Clinic Proceedings ·Ayalew Tefferi, Mark E. Bolander, Stephen M. Ansell, Eric D. Wieben, Thomas C. Spelsberg	2002	40
8	Effects of orbital spaceflight on human osteoblastic cell physiology and gene expression Bone ·Steven A. Harris, M. Zhang, Louis S. Kidder, Glenda L. Evans, Thomas C. Spelsberg, Russell T. Turner	2000	42
9	Identification of breast cancer cell line-derived paracrine factors that stimulate osteoclast activity. PubMed ·Larry Pederson, Bent Winding, Niels T. Foged, Thomas C. Spelsberg, Merry Jo Oursler	1999	72
10	Osteoclasts and transforming growth factor-beta: estrogen-mediated isoform-specific regulation of production. Endocrinology ·John A. Robinson, B. Lawrence Riggs, Thomas C. Spelsberg, Merry Jo Oursler	1996	33
11	The ubiquitous nature of the progesterone receptor binding factor‐1 (RBF‐1) in avian tissues Journal of Cellular Biochemistry ·James P. Landers, Malayannan Subramaniam, Barbara Gosse, Rebecca Weinshilboum, Benjamin J. Madden, Thomas C. Spelsberg	1994	6
12	Immunohistochemical localization of the avian progesterone receptor and its candidate receptor binding factor (RBF‐1) Journal of Cellular Biochemistry ·Yihui Zhuang, James P. Landers, Mark D. Schuchard, Heimo Syvälä, Barbara Gosse, Terry Ruesink, Thomas C. Spelsberg, Pentti Tuohimaa	1993	4
13	High-performance capillary electrophoresis of glycoproteins: The use of modifiers of electroosmotic flow for analysis of microheterogeneity Analytical Biochemistry ·James P. Landers, Robert P. Oda, Benjamin J. Madden, Thomas C. Spelsberg	1992	103
14	Evidence of Steroid Receptors in Human Osteoblast-Like Cells Connective Tissue Research ·Douglas S. Colvard, Thomas C. Spelsberg, Erik Fink Eriksen, Philip E. Keeting, B. Lawrence Riggs	1989	17
15	Steroid Action on Gene Expression: Possible Roles of Regulatory Genes and Nuclear Acceptor Sites1 Biology of Reproduction ·Thomas C. Spelsberg, Charles Rories, J. J. Rejman, Amy Goldberger, Kyle D. Fink, Chris Lau, Douglas S. Colvard, Gregory A. Wiseman	1989	47
16	Characterization of the chromatin acceptor sites for the avian oviduct progesterone receptor using monoclonal antibodies Biochemistry ·Amy Goldberger, Michael Horton, Jerry A. Katzmann, Thomas C. Spelsberg	1987	8
17	The androgen receptor in normal human foreskin American Journal of Obstetrics and Gynecology ·Anthony J. Razel, Jan Olof Svensson, Thomas C. Spelsberg, Carolyn B. Coulam	1985	1
18	Characterization of Epstein-Barr Virus Nuclear Antigen(s) in Different Cell Lines by Radioimmunoelectrophoresis Intervirology ·Thomas B. Sculley, Thomas C. Spelsberg, Gary R. Pearson	1984	5
19	Visualization of nonfunctioning adrenal adenomas with iodocholesterol: possible relationship to subcellular distribution of tracer. PubMed ·Robert A. Rizza, Heinz W. Wahner, Thomas C. Spelsberg, Robert C. Northcutt, Harold L. Moses	1978	33
20	Competitive binding and metabolism of several carcinogenic polycyclic aromatic hydrocarbons by AKR mouse embryo cells in culture. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Thomas H. Zytkovicz, Harold L. Moses, Thomas C. Spelsberg	1978	5

About Thomas C. Spelsberg

Thomas C. Spelsberg is a scholar working on Genetics, Molecular Biology, Orthopedics and Sports Medicine, Oncology and Animal Science and Zoology, having authored 264 papers that have together received 17.8k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (86 papers), Bone Metabolism and Diseases (62 papers), TGF-β signaling in diseases (34 papers), DNA and Nucleic Acid Chemistry (28 papers), Bone health and treatments (26 papers), RNA Research and Splicing (16 papers), Genomics and Chromatin Dynamics (16 papers) and Animal Nutrition and Physiology (15 papers). The work is most often cited by research in Orthopedics and Sports Medicine (2.7k citations), Genetics (5.1k citations), Oncology (4.3k citations), Molecular Biology (10.1k citations) and Endocrinology, Diabetes and Metabolism (2.0k citations). Thomas C. Spelsberg has collaborated with scholars based in United States, France and Canada. Frequent co-authors include B. Lawrence Riggs, Malayannan Subramaniam, Sundeep Khosla, Lorenz C. Hofbauer, Colin R. Dunstan, Merry Jo Oursler, Douglas S. Colvard, Steven A. Harris, David L. Lacey and David J. Rickard. Their work appears in journals such as Journal of Cellular Biochemistry, Endocrinology, Journal of Bone and Mineral Research, Biochemistry and American Journal of Obstetrics and Gynecology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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