Sylvia Heink

4.7k total citations · 2 hit papers
23 papers, 3.1k citations indexed

About

Sylvia Heink is a scholar working on Immunology, Molecular Biology and Oncology. According to data from OpenAlex, Sylvia Heink has authored 23 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Immunology, 6 papers in Molecular Biology and 6 papers in Oncology. Recurrent topics in Sylvia Heink's work include Immunotherapy and Immune Responses (9 papers), T-cell and B-cell Immunology (9 papers) and Immune Cell Function and Interaction (8 papers). Sylvia Heink is often cited by papers focused on Immunotherapy and Immune Responses (9 papers), T-cell and B-cell Immunology (9 papers) and Immune Cell Function and Interaction (8 papers). Sylvia Heink collaborates with scholars based in Germany, United States and Canada. Sylvia Heink's co-authors include Thomas Korn, Stefan Rose‐John, Christoph Garbers, Elke Krüger, Peter‐M. Kloetzel, Thomas Kamradt, Magdalena Huber, Anne Brüstle, Michael Lohoff and Bernhard Hemmer and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

Sylvia Heink

23 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The development of inflammatory TH-17 cells requires interferon-regulatory factor 4

2007 540 citations Anne Brüstle, Sylvia Heink et al. Nature Immunology profile →
Interleukin-6: designing specific therapeutics for a complex cytokine

2018 466 citations Christoph Garbers, Sylvia Heink et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sylvia Heink Germany	20	1.8k	936	592	306	265	23	3.1k
Azzam A. Maghazachi Norway	37	2.5k 1.4×	1.2k 1.3×	1.0k 1.7×	333 1.1×	289 1.1×	114	4.2k
Idit Shachar Israel	34	2.5k 1.4×	804 0.9×	519 0.9×	300 1.0×	169 0.6×	83	3.6k
Anne Brüstle Germany	22	2.0k 1.1×	555 0.6×	468 0.8×	228 0.7×	171 0.6×	36	2.8k
Kristine Kikly United States	22	2.1k 1.1×	1.0k 1.1×	643 1.1×	191 0.6×	270 1.0×	32	3.4k
Jennifer Major United States	26	1.5k 0.8×	893 1.0×	597 1.0×	141 0.5×	305 1.2×	37	2.9k
Anna Cabrelle Italy	33	1.8k 1.0×	1.2k 1.2×	994 1.7×	423 1.4×	198 0.7×	60	3.7k
Carol Anne Ogden United States	16	2.3k 1.3×	795 0.8×	345 0.6×	255 0.8×	223 0.8×	20	3.2k
Natalia V. Giltiay United States	22	1.3k 0.7×	598 0.6×	317 0.5×	228 0.7×	145 0.5×	37	2.1k
Friederike Berberich‐Siebelt Germany	32	1.8k 1.0×	1.4k 1.5×	621 1.0×	165 0.5×	287 1.1×	59	3.1k
Fredrik Ivars Sweden	27	2.1k 1.1×	1.2k 1.3×	407 0.7×	118 0.4×	200 0.8×	68	3.5k

Countries citing papers authored by Sylvia Heink

Since Specialization

Citations

This map shows the geographic impact of Sylvia Heink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sylvia Heink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sylvia Heink more than expected).

Fields of papers citing papers by Sylvia Heink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sylvia Heink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sylvia Heink. The network helps show where Sylvia Heink may publish in the future.

Co-authorship network of co-authors of Sylvia Heink

This figure shows the co-authorship network connecting the top 25 collaborators of Sylvia Heink. A scholar is included among the top collaborators of Sylvia Heink based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sylvia Heink. Sylvia Heink is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Nejad, Elham Beyranvand, Marit J van Elsas, Jan Willem Kleinovink, et al.. (2021). IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors. Journal for ImmunoTherapy of Cancer. 9(4). e002460–e002460. 27 indexed citations

Heink, Sylvia, Felix S.R. Picard, Julia Zeiträg, et al.. (2020). Salt generates antiinflammatory Th17 cells but amplifies pathogenicity in proinflammatory cytokine microenvironments. Journal of Clinical Investigation. 130(9). 4587–4600. 50 indexed citations

Mufazalov, Ilgiz A., Sylvia Heink, Yilang Tang, et al.. (2020). Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression. The Journal of Immunology. 204(4). 747–751. 6 indexed citations

Fecher, Caroline, Laura Trovò, Stephan A. Müller, et al.. (2019). Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. Nature Neuroscience. 22(10). 1731–1742. 205 indexed citations

Garbers, Christoph, Sylvia Heink, Thomas Korn, & Stefan Rose‐John. (2018). Interleukin-6: designing specific therapeutics for a complex cytokine. Nature Reviews Drug Discovery. 17(6). 395–412. 466 indexed citations breakdown →

Rothhammer, Veit, Andreas Muschaweckh, Georg Gasteiger, et al.. (2014). α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets. Acta Neuropathologica Communications. 2(1). 27–27. 20 indexed citations

Freitag, Jenny, Sylvia Heink, Edith Roth, et al.. (2014). Towards the Generation of B-Cell Receptor Retrogenic Mice. PLoS ONE. 9(10). e109199–e109199. 9 indexed citations

Knier, Benjamin, Veit Rothhammer, Sylvia Heink, et al.. (2014). Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis. Journal of Autoimmunity. 56. 34–44. 47 indexed citations

Heink, Sylvia, Franziska Petermann, Ajithkumar Vasanthakumar, et al.. (2014). IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1. Nature Communications. 5(1). 3770–3770. 85 indexed citations

10.

Huber, Magdalena, Sylvia Heink, Axel Pagenstecher, et al.. (2012). IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. Journal of Clinical Investigation. 123(1). 247–260. 190 indexed citations

11.

Loschko, Jakob, Sylvia Heink, Diana Dudziak, et al.. (2011). Antigen Targeting to Plasmacytoid Dendritic Cells via Siglec-H Inhibits Th Cell-Dependent Autoimmunity. The Journal of Immunology. 187(12). 6346–6356. 85 indexed citations

12.

Berod, Luciana, Sylvia Heink, Christine Stadelmann, et al.. (2011). PI3Kγ deficiency delays the onset of experimental autoimmune encephalomyelitis and ameliorates its clinical outcome. European Journal of Immunology. 41(3). 833–844. 26 indexed citations

13.

Rothhammer, Veit, Sylvia Heink, Franziska Petermann, et al.. (2011). Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE. The Journal of Experimental Medicine. 208(12). 2465–2476. 204 indexed citations

14.

Petermann, Franziska, Veit Rothhammer, Malte Christian Claussen, et al.. (2010). γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism. Immunity. 33(3). 351–363. 228 indexed citations

15.

Huber, Magdalena, Sylvia Heink, Anna Guralnik, et al.. (2009). A Th17‐like developmental process leads to CD8⁺ Tc17 cells with reduced cytotoxic activity. European Journal of Immunology. 39(7). 1716–1725. 184 indexed citations

16.

Brüstle, Anne, Sylvia Heink, Magdalena Huber, et al.. (2007). The development of inflammatory TH-17 cells requires interferon-regulatory factor 4. Nature Immunology. 8(9). 958–966. 540 indexed citations breakdown →

17.

Heink, Sylvia, et al.. (2007). The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum. EMBO Reports. 8(12). 1170–1175. 76 indexed citations

18.

Seifert, Ulrike, et al.. (2005). Interferon‐γ, the functional plasticity of the ubiquitin–proteasome system, and MHC class I antigen processing. Immunological Reviews. 207(1). 19–30. 180 indexed citations

19.

Heink, Sylvia, Daniela Ludwig, Peter‐M. Kloetzel, & Elke Krüger. (2005). IFN-γ-induced immune adaptation of the proteasome system is an accelerated and transient response. Proceedings of the National Academy of Sciences. 102(26). 9241–9246. 221 indexed citations

20.

Heink, Sylvia, et al.. (2003). Human immunodeficiency virus‐1 Tat protein interacts with distinct proteasomal α and β subunits. FEBS Letters. 553(1-2). 200–204. 69 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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