Sophia Y. Breusegem

2.4k total citations · 1 hit paper
29 papers, 1.8k citations indexed

About

Sophia Y. Breusegem is a scholar working on Molecular Biology, Cell Biology and Nephrology. According to data from OpenAlex, Sophia Y. Breusegem has authored 29 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 9 papers in Cell Biology and 7 papers in Nephrology. Recurrent topics in Sophia Y. Breusegem's work include Cellular transport and secretion (8 papers), Parathyroid Disorders and Treatments (7 papers) and Ion Transport and Channel Regulation (5 papers). Sophia Y. Breusegem is often cited by papers focused on Cellular transport and secretion (8 papers), Parathyroid Disorders and Treatments (7 papers) and Ion Transport and Channel Regulation (5 papers). Sophia Y. Breusegem collaborates with scholars based in United Kingdom, United States and Spain. Sophia Y. Breusegem's co-authors include Matthew Seaman, Michael E. Harbour, David C. Rubinsztein, Moshe Levi, Kévin Moreau, María Jiménez-Sánchez, Eszter Zavodszky, Robert M. Clegg, Frank G. Loontiens and Nicholas P. Barry and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Sophia Y. Breusegem

29 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

2014 351 citations Eszter Zavodszky, Matthew Seaman et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sophia Y. Breusegem United Kingdom	21	950	611	343	285	221	29	1.8k
Georg Christoph Korenke Germany	25	914 1.0×	175 0.3×	410 1.2×	33 0.1×	143 0.6×	57	1.7k
Angela R. Aldred Australia	20	928 1.0×	447 0.7×	254 0.7×	36 0.1×	98 0.4×	27	1.8k
A Franchi France	25	2.9k 3.0×	321 0.5×	377 1.1×	89 0.3×	51 0.2×	33	3.7k
Nelson Quintana United States	19	1.0k 1.1×	469 0.8×	382 1.1×	26 0.1×	150 0.7×	36	1.9k
Yosuke Funato Japan	25	1.3k 1.4×	322 0.5×	140 0.4×	176 0.6×	78 0.4×	50	2.2k
Randy S. Haun United States	28	1.3k 1.4×	387 0.6×	109 0.3×	61 0.2×	153 0.7×	52	2.2k
Pedro Brites Portugal	22	1.4k 1.4×	172 0.3×	453 1.3×	21 0.1×	102 0.5×	41	1.9k
Michela Rugolo Italy	35	3.3k 3.5×	248 0.4×	401 1.2×	20 0.1×	195 0.9×	98	4.0k
Garry K. Brown United Kingdom	39	2.8k 2.9×	148 0.2×	363 1.1×	35 0.1×	85 0.4×	91	3.8k
Darryl R. Peterson United States	26	727 0.8×	80 0.1×	187 0.5×	141 0.5×	70 0.3×	61	1.8k

Countries citing papers authored by Sophia Y. Breusegem

Since Specialization

Citations

This map shows the geographic impact of Sophia Y. Breusegem's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sophia Y. Breusegem with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sophia Y. Breusegem more than expected).

Fields of papers citing papers by Sophia Y. Breusegem

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sophia Y. Breusegem. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sophia Y. Breusegem. The network helps show where Sophia Y. Breusegem may publish in the future.

Co-authorship network of co-authors of Sophia Y. Breusegem

This figure shows the co-authorship network connecting the top 25 collaborators of Sophia Y. Breusegem. A scholar is included among the top collaborators of Sophia Y. Breusegem based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sophia Y. Breusegem. Sophia Y. Breusegem is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Breusegem, Sophia Y., Katherine A. Kentistou, Ken K. Ong, et al.. (2025). A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation. Nature Communications. 16(1). 1681–1681. 1 indexed citations

Son, Sung Min, So Jung Park, Sophia Y. Breusegem, Delphine Larrieu, & David C. Rubinsztein. (2024). p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome. Nature Cell Biology. 26(2). 235–249. 20 indexed citations

Janssen, Anne F. J., et al.. (2022). The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor–Guillermo progeria syndrome cells. Nucleic Acids Research. 50(16). 9260–9278. 23 indexed citations

Janssen, Anne F. J., Sophia Y. Breusegem, & Delphine Larrieu. (2022). Current Methods and Pipelines for Image-Based Quantitation of Nuclear Shape and Nuclear Envelope Abnormalities. Cells. 11(3). 347–347. 27 indexed citations

Mukadam, Aamir S., Sophia Y. Breusegem, & Matthew Seaman. (2018). Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing. Cellular and Molecular Life Sciences. 75(14). 2613–2625. 20 indexed citations

Larrieu, Delphine, Emmanuelle Viré, Samuel C. Robson, et al.. (2018). Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway. Science Signaling. 11(537). 67 indexed citations

Rovelet‐Lecrux, Anne, Camille Charbonnier, David Wallon, et al.. (2015). De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease. Molecular Psychiatry. 20(9). 1046–1056. 74 indexed citations

Breusegem, Sophia Y. & Matthew Seaman. (2014). Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval. Cell Reports. 9(5). 1931–1945. 41 indexed citations

Zavodszky, Eszter, Matthew Seaman, Kévin Moreau, et al.. (2014). Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy. Nature Communications. 5(1). 3828–3828. 351 indexed citations breakdown →

10.

Breusegem, Sophia Y. & Matthew Seaman. (2013). Image-Based and Biochemical Assays to Investigate Endosomal Protein Sorting. Methods in enzymology on CD-ROM/Methods in enzymology. 534. 155–178. 16 indexed citations

11.

Jiménez, Carlos, Juan M. Capasso, Charles L. Edelstein, et al.. (2009). Different ways to die: cell death modes of the unicellular chlorophyte Dunaliella viridis exposed to various environmental stresses are mediated by the caspase-like activity DEVDase. Journal of Experimental Botany. 60(3). 815–828. 109 indexed citations

12.

Breusegem, Sophia Y., Hideaki Takahashi, Xiaoxin Wang, et al.. (2009). Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency. American Journal of Physiology-Renal Physiology. 297(2). F350–F361. 64 indexed citations

13.

Villa‐Bellosta, Ricardo, M. Barac‐Nieto, Sophia Y. Breusegem, et al.. (2007). Interactions of the growth-related, type IIc renal sodium/phosphate cotransporter with PDZ proteins. Kidney International. 73(4). 456–464. 43 indexed citations

14.

Levi, Moshe, Judith Blaine, Sophia Y. Breusegem, et al.. (2006). Renal Phosphate–Wasting Disorders. Advances in Chronic Kidney Disease. 13(2). 155–165. 4 indexed citations

15.

Breusegem, Sophia Y., Moshe Levi, & Nicholas P. Barry. (2006). Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging Microscopy. Nephron Experimental Nephrology. 103(2). e41–e49. 20 indexed citations

16.

Lanaspa, Miguel A., Héctor Giral, Sophia Y. Breusegem, et al.. (2006). Interaction of MAP17 with NHERF3/4 induces translocation of the renal Na/Pi IIa transporter to thetrans-Golgi. American Journal of Physiology-Renal Physiology. 292(1). F230–F242. 47 indexed citations

17.

Breusegem, Sophia Y., Nabil Halaihel, Makoto Inoue, et al.. (2005). Acute and chronic changes in cholesterol modulate Na-P_icotransport activity in OK cells. American Journal of Physiology-Renal Physiology. 289(1). F154–F165. 26 indexed citations

18.

McWilliams, Ryan, et al.. (2005). Shank2E binds NaP_i cotransporter at the apical membrane of proximal tubule cells. American Journal of Physiology-Cell Physiology. 289(4). C1042–C1051. 23 indexed citations

19.

Inoue, Makoto, Michelle A. Digman, Sophia Y. Breusegem, et al.. (2004). Partitioning of NaPi Cotransporter in Cholesterol-, Sphingomyelin-, and Glycosphingolipid-enriched Membrane Domains Modulates NaPi Protein Diffusion, Clustering, and Activity. Journal of Biological Chemistry. 279(47). 49160–49171. 40 indexed citations

20.

Breusegem, Sophia Y., Frank G. Loontiens, Peter Regenfuß, & Robert M. Clegg. (2001). Kinetics of binding of hoechst dyes to DNA studied by stopped-flow fluorescence techniques. Methods in enzymology on CD-ROM/Methods in enzymology. 340. 212–233. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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